Conserved Protein Domain Family
DAP2

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COG1506: DAP2 
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 224423
Aligned: 48 rows
Threshold Bit Score: 247.828
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
461915    58 EATIDVTDVPQTPFLQEQYSMRPRRESFQFNDIenqhhthsffsvnkfnrrwGEWSLPEKRSYVLVfTLIALsvlvllVI 137  baker's yeast
15888182     --------------------------------------------------------------------------------      Agrobacterium tume...
16126393  16 STPALAQKLTPERIFGDPSLSGPTARGVALSPDgkrv------------tylKGKPEAANIQDLWA-ADVKGgepyrlID 82   Caulobacter cresce...
16126906  14 AASVAFAALSSGAALAADDYKAPPAPIAQILDAaptpsia-----vspdrkiLAQLGRENLPSIAAvSEPILrlggyrLN 88   Caulobacter cresce...
16126943  21 ATPFTVDQLLDQQRLGVVRIDPSQRWLVIPTTGpyrsa----------rswaLEFDTAMTITRLSV-VDLRTdgpprpLL 89   Caulobacter cresce...
19115832   3 VSHFGESIFLPYHQDIEWITSTEGTVLYYDQST-------------------FSLSLFYPDGKEYG-SNVDSl----iTS 58   fission yeast
19114882  28 ALALIFSLLILYLTISNVSDSPPKRDSLSLDDIv------------------LQKYKPSYKQVNWIdSQGLKdtflvkYG 89   fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140   7 LCDSPTVRVPTLVCVPDLHHARHVQRTIPVATRfaslptspafqvmiprttpMPSRRDLCFTLLTLvMTASFgvipafAD 86   Xylella fastidiosa...
729295    16 FDTKKKHLLDKLIRVGIILVLLIWGTVLLLKSIph----------------hSNTPDYQEPNSNYT-NDGKLkvsfsvVR 78   baker's yeast
461915   138 LIPSKLLPTKITRpkts-agdsSLGKRSFSIENvlngdfaipedtfhfidppqrllgqdsdpglyfTTKEIdghtnFIAK 216  baker's yeast
15888182     --------------------------------------------------------------------------------      Agrobacterium tume...
16126393  83 SAALSSGDKELSEaeka--rreRARVSARGIVEys-----------------------------wdRQGRFilvplDGDL 131  Caulobacter cresce...
16126906  89 PRNNGPIEARSAWmnal-sfqdVATGKTRAVALpagarfla-----------------pswspdggKMAFImdgkqSLEL 150  Caulobacter cresce...
16126943  90 AGTAGAWDSDADFgytp--gpfAPSGARMAVVRardaslevgivtla-----tgavvwtglfpvsdVWGRSmqwidDDRL 162  Caulobacter cresce...
19115832  59 FVLTCKNLHRKRY---------SSDMEYIAFSCs---------------------------------KDRRwrhsyYEDV 96   fission yeast
19114882  90 DLINIQDPYNLNKtlfs-vsdlVYNGIQLDYDSysisfda-------------------kyvlvsvNKSQRwrhssFAQY 149  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140  87 YRTPPEHILKVLKapltptpslDPTGQRLLLTTqqtypsitrvaqpylk--lagvrleprnrsrhdTPGGYgipscVAHF 164  Xylella fastidiosa...
729295    79 NNTFQPKYHELQWisdn-kiesNDLGLYVTFMNdsyvvksvyddsyn-----svllegktfihngqNLTVEsitasPDLK 152  baker's yeast
461915   217 QLFDETfEvnlggnrfLYEGVEFTVSTVQINYKLDKLIFgtnlesefr----hsskgfywiKDLNTgniepilpPEKSDD 292  baker's yeast
15888182     --------------------------------------------------------------------------------      Agrobacterium tume...
16126393 132 YLDAVAdGki-----trLTETPGDEVDAKVSPKGGYVSYvrdqnl----------yikpvaGGAET--------ALTTDG 188  Caulobacter cresce...
16126906 151 WVVDVKaAtar--kasDIAISGVFGAGYDWLPDGSGFLVqavptgrga----ppvkdltpsGPTIQeskgrtaaIRTYQD 224  Caulobacter cresce...
16126943 163 LILAKDpDapamgaltGTQTQARLIEKWRQTREGRAGVTllgagryle----rtptappsrLVAVD--------ADSGKG 230  Caulobacter cresce...
19115832  97 YLVERAtGri----ehLASDQSKKIVVAEWSPIGHKLVYglgsnlf--------iwesfsePPVCIt------dQSDLDG 158  fission yeast
19114882 150 YLYNTEtKdvn---mlGQDNEHWTISLAEWSPTGHQLSFvynndlyvr-----kndgnvqrLTYDG--------TVDVFN 213  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140 165 SLIEIVgGre----tpVQLPPGACPGMALWSPDGQRFVFqnvasdsvelwigdaatghirhIPDVRlnpifghtVQWLGG 240  Xylella fastidiosa...
729295   153 RLLIRTnSvqnwrhstFGSYFVYDKSSSSFEEIGNEVALaiwspnsnd----iayvqdnniYIYSA--------ISKKTI 220  baker's yeast
461915   293 NyelglsklsyAH---------FSPAYNYIYFVYENnlflqqvnsgvakkvtedgskdiFNAKPDWIYEEEVlasdQAIW 363  baker's yeast
15888182     --------------------------------------------------------------------------------      Agrobacterium tume...
16126393 189 Kd--------aLS---------FGVAEFIVQEELDRftgyw--------------wspdESRIVYTRVDESGvdivPRAD 237  Caulobacter cresce...
16126906 225 LltnahdealfDY---------YFTAQLTRVDLADGkatavgkp-------giissfsvSPDGQYVLTNRLKrpysYLVP 288  Caulobacter cresce...
16126943 231 Qv--------lAQ---------GAFIDLEVAPGGRRaamleetellhpdpwrpayttdpSRRRRLVVVDLTSgamwKPCR 293  Caulobacter cresce...
19115832 159 LfngnsdwvyeEE---------ILQSSKAVWWSPDGnclsylsidd----skvpvhvlpFEQLDSKVEDQNRvnnfFHYS 225  fission yeast
19114882 214 Gltdw---iyeEE---------VLSSPSTIWWSPDSdkiaflklneseiptyhyplytaELDPSLPEFDYNKdmaiKYPK 281  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140 241 SsklllklvppHQglpptntpgTAGPDIQETFGGKGqsstyetrdtl-asayddslfayYGASQLAVLDIGTg--vLRPV 317  Xylella fastidiosa...
729295   221 RavtndgssflFN---------GKPDWVYEEEVFEDdkaawwsptgdylaflkidesevGEFIIPYYVQDEKdiypEMRS 291  baker's yeast
461915   364 WAPDDSKAVFARFNDTSVDDIRLNRYTNmneaylsdtkikyPKPGFQNPQFDLFlvnlQNGIIYSINTGGQKdsilyngk 443  baker's yeast
15888182     --------------------------------------------------------------------------------      Agrobacterium tume...
16126393 238 IGPGGATVVNQRYPRAGRPNAVVDLFVRd-----------lASGKVTALDLGANkdiyVARVAWSADGKTVYvqrlsr-- 304  Caulobacter cresce...
16126906 289 AGQFPTEIAVSTIGGQPVKTLVDRPLADn------------LPPAFDAVPTGVRsvswRADAPATLVWAEAQdggdprk- 355  Caulobacter cresce...
16126943 294 TCEVATDLLAWSPSGRQLLVYAKPDAAEw-----------tAARYWRLNAVTQRlaplDDAGVETRAETTRYgsrvprad 362  Caulobacter cresce...
19115832 226 TPKDPIPFVKLFVNCFTDSGESIEVDSS--------------FPLSTQHRYITDvawaGNEKLMFVEVLRGNy------- 284  fission yeast
19114882 282 PGNPNPSVSLFVADLNSNASSNFSLWHNe-----------pLAEPVVQNVLWVN----TSSVLVQFTNRNSTc------- 339  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140 318 GVPALYDSVTGAPDGLHVLTAAIQPPYShavtyqrfardiaVLDLVKNASAPIArlplADRVPVYGVPEGPRdfdwrptd 397  Xylella fastidiosa...
729295   292 IKYPKSGTPNPHAELWVYSMKDGTSFHPr-----------iSGNKKDGSLLITEvtwvGNGNVLVKTTDRSSd------- 353  baker's yeast
461915   444 wispdt-----frfeitdrnskilDVKVYDIPSSQMLTVRNTNSNLfNGWIEKTKDILSippkpelkrmDYGYIDIHads 518  baker's yeast
15888182     --------------------------------------------------------------------------------      Agrobacterium tume...
16126393 305 -------------------dqktlDLLAFDAATGAGKTILTDTDPHfIEVSNDFRPLTDgt-------fLWGSEKDGnqh 358  Caulobacter cresce...
16126906 356 -----------------kvaihdsVFMQAAPFDGAPTKLIDLEQRYrGVEWGRGDVALLtsrww-qtrnQKLILIDPskp 417  Caulobacter cresce...
16126943 363 wmgedp-----lilarvggapanpDDWVRWTAEGPRTLTGGLPPGPrALEATSPTAIIVsq-------aGKLWRIDGqgr 430  Caulobacter cresce...
19115832 285 -----------------------eRVTSLFDLSSRKTTIENTEVSEhPLALTSSLHLKYlsf----eslGNLKERYVrq- 336  fission yeast
19114882 340 ------------------------ITARLLDTELKSIHTVKTECLEeGWYEVQQSAKMFplnnslvwenWSDGYFDIlal 395  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140 398 patlvwaeaqdhgdwninvphrdhLMLLQAPFTTKPVEIARTVQRFdGFDWTAQPDIAFlseedenrhwRRTRIVDLdhp 477  Xylella fastidiosa...
729295   354 -----------------------iLTVFLIDTIAKTSNVVRNESSNgGWWEITHNTLFIpane--tfdrPHNGYVDIlpi 408  baker's yeast
461915   519 rgfshlfyYPTVFAkepiQlTKGNWEVTGNgivgyeYETDTIFFTANEIgvmSQHLYSISLTDSTTQntfqSLQNPSDKY 598  baker's yeast
15888182   1 ------------------------------------MPDKRFLSSAFGQeesGTSIPSLTRRSLLAG----AMGLSAAAF 40   Agrobacterium tume...
16126393 359 ------lyRYAADGkliaQiTKGDWPVIGLegv-deARKVAIFSASIDT---PIERRLYEVSYAKPG----KPKALTSAG 424  Caulobacter cresce...
16126906 418 gt-grvivDRNYQDryndPgRAVTRRDARGedllhfTPDGKSVFVVGDGasaKGEFPFVGRMSLADGkvtkLWQAQAPYY 496  Caulobacter cresce...
16126943 431 ------arLLATSArianLgATGGERLAFNh-----RPAIDTLVLAWPG---PGGLTLGGVQDYRLR----RLGLTTAPG 492  Caulobacter cresce...
19115832 337 -------yFLSNKKriaiYeLDNPVPIYLTpvnisfLSDLYLINNTLYFtaiSSGSPFSRVYRLCTKslilSEINIQIGS 409  fission yeast
19114882 396 dd-ynhlaFIPFNGsspiYlTSGAWDVTDGpih-idGDFGNVYFLATLKdstERHLYYVSLDTLEIY----GITDNGEDE 469  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140 478 ahperilwDLSSDEryadPgAFIYHLLPNGts--vvRQDGHAVYLSGQGaspQGDRPFLDRLDLNTLk--tQRLFRSNSA 553  Xylella fastidiosa...
729295   409 ggynhlayFENSNSshykTlTEGKWEVVNGpla-fdSMENRLYFISTRKsstERHVYYIDLRSPNEI----IEVTDTSED 483  baker's yeast
461915   599 DFYDFE-LssSARYAISKKLGPDTPIKVAGPLTrvl--nvAEIHDDSILQLTKDEKfkek---------iknYDLPITSY 666  baker's yeast
15888182  41 LPPRAKaGivAPEVLPLERQDYAEARKRFHTH---------LLRKMAAPEKSSVLG----------------TPPGAERV 95   Agrobacterium tume...
16126393 425 GWWAAK-VadNGGAFAGTYSDPKTPSQTALYSAdgkrvrwIEENKLAEGHPYWPYA----------------ANLPQPEF 487  Caulobacter cresce...
16126906 497 QVPVAL-AdeAGKTVITRRESAKEQPNFYIQAVa-----pGAKAKALTSFPDRAPQ----------------FAGVTKQT 554  Caulobacter cresce...
16126943 493 ERILVA-AgrVGAVASLEQDAQGVERLILRRR--------DHPARTLVTLNAQLAR----------------VDFARPRA 547  Caulobacter cresce...
19115832 410 GLFGIK-VsnDQNYLLVNYLGPEIPKQFIYSIHedkvstsNDHSKNNLPSDSSSTSlgkvklelcnsletneELIITKEK 488  fission yeast
19114882 470 GYYSTS-FspFGDFYVLNYHGPDVPWQELRSTK-------DKDYCLSLETNSRLKQql------------ssITLPSVEY 529  fission yeast
15898272     --------------------------------------------------------------------------------      Sulfolobus solfata...
15839140 554 AYEQFLgFvpEPGKFLTWHQTVIDPPNAFLRTLgpqhptpAQGEPAYASSTARITHitdp---------tpeVRQIKKRL 624  Xylella fastidiosa...
729295   484 GVYDVS-FssGRRFGLLTYKGPKVPYQKIVDFHsrkaekcDKGNVLGKSLYHLEKNevlt---------kilEDYAVPRK 553  baker's yeast
461915   667 KTMVLDDGv-------EINYIEIKPANLNPKKK------YPILVNIYGGPg------SQTFTtkS--SLAFEQAVVSGLD 725  baker's yeast
15888182  96 TYPGGPDGs------iELVAWLSHYQPSKTLK--------PAVLFLHGGN-------ATGDG------HWALMKPYWEAG 148  Agrobacterium tume...
16126393 488 GSLKAADGe-------TLHYEILKPIGFDPAKK------YPAIVSVYGGP-------HAQRVmkN--WHSPSERTYLEAG 545  Caulobacter cresce...
16126906 555 ITYKRADGv-------TLSGVLYLPPGYDKAKDg----pLPLLMWAYPAEf-----tDAAVAsqTvdEGNRFTRPGGSSH 618  Caulobacter cresce...
16126943 548 VRHQGPRGq-------TLTSWLYLPPGRSAGRKaplitiPYLGRDYPGPP-------ASQNApaR--QVFLNAQILAGAG 611  Caulobacter cresce...
19115832 489 FAFPSVFFkvikvkniTAYIQEIRPPNFNPRKR------YPTVFHLYGAPq------SALVTg----KYEMDINELMASV 552  fission yeast
19114882 530 GKLTFNDT--------TFNFMERRPRNFDVNKK------YPVLFFAYGGPg------SQQVAklFrvDFQAYLASHPDFE 589  fission yeast
15898272   1 ----------------------------------------------------------------------------MMKS 4    Sulfolobus solfata...
15839140 625 VTYKRNDGv-------DLSFTLYTPPDYQEGQR------LPAILYAYPTDfanstqaGQVTGsqHtfTRLPYYRLLLLAG 691  Xylella fastidiosa...
729295   554 SFRELNLGkdefgkdiLVNSYEILPNDFDETLSd----hYPVFFFAYGGPn------SQQVVktF--SVGFNEVVASQLN 621  baker's yeast
461915   726 VIVLQIEPRGTGGKGWSFRSWAREKLGYWEPRDITEVTKkFIq--RNSQHIDESKIAIWGWSYGGFTSLKTVELDNgdTF 803  baker's yeast
15888182 149 YVVLLPSFRGENG------QSGHYSGFYNETADALAAAT-YL---ENLPGIDRNRFFIAGHSNGGTLTLLAAMSRK---F 215  Agrobacterium tume...
16126393 546 YVIFKLDNRGSGNRSAKFMRALDRKLGTVEVEDQLLGAK-FL---ASQPYVDADKLGVMGWSYGGFMALMLLTAENt-PF 620  Caulobacter cresce...
16126906 619 LFLLTQGYAILDNPAFPIIGQNGAEPNDTYIEQLTADAKaAVdavVAMGVADRDRIAVGGHSYGAFMTANLLAHTR--LF 696  Caulobacter cresce...
16126943 612 YAVLLPSLP---------IDPDR-EPAQGLADQILKVVDaAA---AQEPLIDSERLALMGHSYGGYTVLTAATQSP--RF 676  Caulobacter cresce...
19115832 553 YNFLVIKVDIVDISDVS-GQHLFSDSHELIIKSWIELLR-SY---VDTPYIDRHRVGIWGWSFGGYLTLKILENAD--FI 625  fission yeast
19114882 590 FIVVTLDGRGTGFNGNAFRYSVSRHLGEWESYDQGQAGK-FW---ADLPFVDENHVGIWGWSYGGYLTLKTLETQD--VF 663  fission yeast
15898272   5 LVIHGKN---SSPEKVEWLAKPLRKFGEVIVPEFEIEAKeGV---EKALTYD--FDCIAGHSRGGLIALIAAALKG--KW 74   Sulfolobus solfata...
15839140 692 YAIIDNASFPIVGD----PKTAYDTYLEQLKADATAAVDkAV----ALGVVDRERIGITGHSHGALMTANLIAHTD--LF 761  Xylella fastidiosa...
729295   622 AIVVVVDGRGTGFKGQDFRSLVRDRLGDYEARDQISAAS-LY---GSLTFVDPQKISLFGWSYGGYLTLKTLEKDGgrHF 697  baker's yeast
461915   804 KYAMAVAPVTNWTLYDSVYTERYMNQPSENHEG----------------------YFEVSTIQNFKSFESLKRLFIVHGT 861  baker's yeast
15888182 216 RAAAPISAGVNSWRYFNRYSDEICFDETDERE-------------------------FIMRSSVCFGPSLKCPALLLRGT 270  Agrobacterium tume...
16126393 621 KAGAAGAPPTEWSLYDTAYTERYMGKPDENKAG-----------------------YAYSDINNRIDKLAPGSLLLLHGM 677  Caulobacter cresce...
16126906 697 RAGIARSGAYNRTLTPFGFQAEQRTYWEATDT-------------------------YTKMSPFTYAPNIKDPILLIHGE 751  Caulobacter cresce...
16126943 677 KAVVASAFSADLIGHYTRKSLSASVLPEAGVTLmgdagwaelgqgrmgappwrdpQRYLRNSPLLAADKITAPVMLIMGD 756  Caulobacter cresce...
19115832 626 KTGAVVAPVTDWRYYDAYYSENLLGAYSKQTTa----------------------IYDKTAVHYSENFRKLCGLLVLHGT 683  fission yeast
19114882 664 SYGMAVAPVTDWRLYDSVYTERYMDLPQYNKEGyk-------------------nSQIHDYEKFKQLKR----FFVAHGT 720  fission yeast
15898272  75 AIAVSAPSDRRKQKEYLSKFPPGTVQYNIYQDLmk-------------------mPEYELEYSSLSYADRLKKVLLIHGE 135  Sulfolobus solfata...
15839140 762 RAGVASSGSYNKTFTPFGFQNERRILWQAKDV-------------------------YLKASPFFYADKIKHPLLLIHGE 816  Xylella fastidiosa...
729295   698 KYGMSVAPVTDWRFYDSVYTERYMHTPQENFDG-----------------------YVESSVHNVTALAQANRFLLMHGT 754  baker's yeast
461915   862 FDDNVHIQ--NTFRLVDQLNLlGLTNYDMHIFPDSDHSIRY-HNAQRIVFQKLYYWLRDAFAER 922  baker's yeast
15888182 271 EERPFDAD--HQLFVDRALTS--GFKIDKKLLPGTHNGVVP--HAVEESIRLFNAFV------- 321  Agrobacterium tumefaciens str. C58...
16126393 678 ADDNVIFE--NSTRLMAALQR-KAILFEMAMYPGERHSAPGsKTKGLSVLKTHLDFFDRKLKGR 738  Caulobacter crescentus CB15
16126906 752 ADDNSGTFpvQSERFYAALKG-AGATVRYVTLPNEAHGYRA-RESTGHTLWEMAQWMDKYVKNA 813  Caulobacter crescentus CB15
16126943 757 LDGDPP----QALTLFGALFR-QDKDAMLLTYHGEGHVVLT-PGNIADEYRRVLDFLKEHIGDG 814  Caulobacter crescentus CB15
19115832 684 SDDNVHIE--NTMQLTKAMVEkGVYNYYPFIVPNANHEFSD-PTDYTFLREKLSGHFHHALYC- 743  fission yeast
19114882 721 GDDNVHFQ--HSMHLMDGLNLaNCYNYDMAVFPDSAHSISY-HNASLSIYHRLSEWIGDALGRI 781  fission yeast
15898272 136 DDEMVLKE--HSITLCDTIKR-MGGDCELHIIPKMKHTPLG--QQYQTIWSIIEDWIKRNSSSF 194  Sulfolobus solfataricus
15839140 817 DDANPGTEpfQSRKFYQAIRG-NGGIAKLVMLPHEPHWYAA-LESNEQFVYEMLNWFDTYVKQA 878  Xylella fastidiosa 9a5c
729295   755 GDDNVHFQ--NSLKFLDLLDLnGVENYDVHVFPDSDHSIRY-HNANVIVFDKLLDWAKRAFDGQ 815  baker's yeast
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