Conserved Protein Domain Family
BrkB

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COG1295: BrkB 
Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase) [Function unknown]
Statistics
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PSSM-Id: 224214
View PSSM: COG1295
Aligned: 63 rows
Threshold Bit Score: 95.0712
Threshold Setting Gi: 14916761
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
17546278   1 MQFDTRVLRQWNVPKLRALQRYALRRAGEDSLPQVAGSLTFTTVLSLVPILTVAFALFTAFPMfQSFRAAIEGYLFSNLV 80  Ralstonia solanacearum
19551908  22 KDEPGLVDKLRDKHDWFDHLMRMNERFGAKGGNQLSAGITYFSVLSIFPIAMLVFGIAGVILAgNPEVLTDIQNRINDAL 101 Corynebacterium glu...
15833656  35 LETVTTTAEKVQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLAsHPMLLQDIFDKILQNI 114 Escherichia coli O1...
15827290   4 PANTGIIDRLRGRFRWLDHVVRAHQRFDERNGSFFAAGLTYYTIFALFPMLMVSFSVVGLVLFrRPELLTTIDDHIRSAV 83  Mycobacterium leprae
15842932   4 LAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSrRPELLTTLEERIRTSV 83  Mycobacterium tuber...
15610471   4 LAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSrRPELLTTLEERIRTSV 83  Mycobacterium tuber...
16766894  40 LHSVTTLMQKIQRQPMVAHLIRATERFNDRLGNQFGAAITYFSFLSMIPIMMVSFAAAGFILAsHPNLLEDIFSKILMNV 119 Salmonella typhimur...
16124112  32 ISHMACLSDRIRAYPAIAHIIRATDRFNDRLGSQFGAAITYFSFLSLIPILMVSFVMVGFVLAsNPDLLAELINKIVNSI 111 Yersinia pestis
15804066  35 LETVTTTAEKVQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLAsHPMLLQDIFDKILQNI 114 Escherichia coli O1...
586684    35 LETVTTTAEKVQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLAsHPMLLQDIFDKILQNI 114 Escherichia coli
17546278  81 PGNISRPILTYLNQFSHNAKGLTAA-GLVGLVVTSVMTMLTV----ENALNAIWRVRQ--RRPLAQR--VLVFWALVSFG 151 Ralstonia solanacearum
19551908 102 EGEIGNTVNGIIDSAIAQRGAVLGI-GGVTALWSGLGWMANL----RFGVSRMWAIDPt-EGNFIQKklTDLVALIVLLL 175 Corynebacterium glu...
15833656 115 SDPTLAATLKNTINTAVQQRTTVGLvGLAVALYSGINWMGNLreaiRAQSRDVWERSPqdQEKFWVKylRDFISLIGLLI 194 Escherichia coli O1...
15827290  84 SS-QLGQELVDLMNRAIDARASVGVvGLATAAWAGLCWMSHF----RAALTKMWWEHHidPSSLLRNklSDLLAMVGTFV 158 Mycobacterium leprae
15842932  84 SG-AVGQQLVDLMNSAIDARASVGViGLATAAWVGLGWMWHL----REALSQMW-AHPvaPAGYLRTklSDLAAMVGTFV 157 Mycobacterium tuber...
15610471  84 SG-AVGQQLVDLMNSAIDARASVGViGLATAAWVGLGWMWHL----REALSQMW-AHPvaPAGYLRTklSDLAAMVGTFV 157 Mycobacterium tuber...
16766894 120 SDPTLASTLKNTINTAVQQRTTVGLvGLGIALYSGVNWMGNLreaiRAQSRDVWERKPqdQEKIWLKylRDFISLIGLLI 199 Salmonella typhimur...
16124112 112 SDPALATTLKNTVNTAIQQRTTVGLtGLAIALYSGISWIGNLreaiRAQSRDVWERNPqdKEKFYYRyaRDFISLIGLVV 191 Yersinia pestis
15804066 115 SDPTLAATLKNTINTAVQQRTTVGLvGLAVALYSGINWMGNLreaiRAQSRDVWERSPqdQEKFWVKylRDFISLIGLLI 194 Escherichia coli O1...
586684   115 SDPTLAATLKNTINTAVQQRTTVGLvGLAVALYSGINWMGNLreaiRAQSRDVWERSPqdQEKFWVKylRDFISLIGLLI 194 Escherichia coli
17546278 152 PVLIGASLSVSSYLVSVSAGY-------VAKLPYGLGVVVGLVPILLSAIAFAMLYVFVPNTLVAWRDAFLAGLVAAVAF 224 Ralstonia solanacearum
19551908 176 AMGVAFGITALGASGLTKNLLdfvglgeIPGISYITWVVAALVGVLANFLVFMWLIFSLPRTKVPMKPGLQAALLGAIGF 255 Corynebacterium glu...
15833656 195 ALIVTLSITSVAGSAQQMIISalh-lnsIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGF 273 Escherichia coli O1...
15827290 159 VFLTTLALTVLSHQAPMAAILrcigithFFVFGVIFQGASVLVSTLVSWLLFTWMIAWLPRKSVNLVASMRGGLIAAVGF 238 Mycobacterium leprae
15842932 158 VIVATIALTVLGHARPMAAVLrwleipqFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGF 237 Mycobacterium tuber...
15610471 158 VIVATIALTVLGHARPMAAVLrwleipqFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGF 237 Mycobacterium tuber...
16766894 200 ALIITLSITSIAGSAQQMIISaly-ldsIEWLKPAWHLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFIAAIGF 278 Salmonella typhimur...
16124112 192 ALIITLSLTSIAGAAQAAIVNalg-lgsIEWLRPAMTLIALSISIAANYLLFLWIFWILPRNKPKKKALLRGALIAAIGF 270 Yersinia pestis
15804066 195 ALIVTLSITSVAGSAQQMIISalh-lnsIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGF 273 Escherichia coli O1...
586684   195 ALIVTLSITSVAGSAQQMIISalh-lnsIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGF 273 Escherichia coli
17546278 225 EIAKRGFGYYVARFPTyTAVYGTFAALPIFLLWIYVSWLVTLLGATIAATLPIIRQgywqrrafpgseffdalgILLLLH 304 Ralstonia solanacearum
19551908 256 EVVKQVGSLLASNALS-NPAGAAFGPIIGIMVVLYLIWRILMYCSAWAATSEEALRlat------------vpaPEPAII 322 Corynebacterium glu...
15833656 274 EVIKIVMTYTLPSLMK-SPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATA----------------------------- 323 Escherichia coli O1...
15827290 239 ELFKQVGSIYLQIVLR-SPAGSVFGPVLGVMVFSYFTAYLVLFAASWAATAELCMK------------------PVS--- 296 Mycobacterium leprae
15842932 238 ELFKQVGAIYLQIVLR-SPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA--------------------------- 289 Mycobacterium tuber...
15610471 238 ELFKQVGAIYLQIVLR-SPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA--------------------------- 289 Mycobacterium tuber...
16766894 279 EVIKIIMTYTLPSLVK-SPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATA----------------------------- 328 Salmonella typhimur...
16124112 271 EVIKFIMTMMLPRLAS-SPSGAAFGSVIGLMAFFYFFARLTLFCAAWIATAHDVAD------------------NRV--- 328 Yersinia pestis
15804066 274 EVIKIVMTYTLPSLMK-SPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATA----------------------------- 323 Escherichia coli O1...
586684   274 EVIKIVMTYTLPSLMK-SPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATA----------------------------- 323 Escherichia coli
17546278 305 RARDHAPR 312 Ralstonia solanacearum
19551908 323 RVRHEIDP 330 Corynebacterium glutamicum ATCC 13032
15833656 324 ----EYKD 327 Escherichia coli O157:H7
15827290 297 ----VQLP 300 Mycobacterium leprae
15842932     -------- Mycobacterium tuberculosis CDC1551
15610471     -------- Mycobacterium tuberculosis H37Rv
16766894 329 ----EYKD 332 Salmonella typhimurium LT2
16124112 329 ----ESKD 332 Yersinia pestis
15804066 324 ----EYKD 327 Escherichia coli O157:H7 EDL933
586684   324 ----EYKD 327 Escherichia coli
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