1FMC,1I01


Conserved Protein Domain Family
FabG

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COG1028: FabG 
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
linked to 3D-structure
Statistics
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PSSM-Id: 223959
View PSSM: COG1028
Aligned: 825 rows
Threshold Bit Score: 35.5638
Threshold Setting Gi: 16265148
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1FMC_A     7 LRLDGKCAIITGAGaGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQ--QLG-GQAFACRCDITSEQELSALADFA 82  Escherichia coli
15614954   1 MKQ--RRVLVTGASgGIGAAISKALAAPHTT-LYLHYYQNERSIDDVRLACeqLQ--AEVVTVKADLSHAAG----VEEL 71  Bacillus halodurans
16078750   1 MN---KTALITGAScGIGKSISETLAARGYN-LLLHYNTNQNAAAELAEKLsqMFG-VNAEILQADLSAQDG----ADKL 71  Bacillus subtilis
19553605  19 ERFFGQGVVVTGAAqGIGMAVAHRIAYEDGN-LVLVDRS-PLVHEVAEELRkaGa--GTVDSFIADLETFEGATDALEFA 94  Corynebacterium glu...
15843143   3 GMLKRKVIVVSGVGpGLGTTLAHRCARDGAD-LVLAARSAERLDDVAKQIIdtGRRaVAVR---TDITDDDDVSNLVQAT 78  Mycobacterium tuber...
15597711   3 DRFRDKVALVSGAAqGIGLGVARRLLEEGAR-VVAVDRS-ELVHELAGDAc------LCLT---ADLERYAECQRVLERT 71  Pseudomonas aerugin...
15599357   1 -MTNHRTALVTGATrGIGLALARRLAASGWS-VVGIAR-HASDDFPGRLLCcdLADpAQTAETLRG-------------L 64  Pseudomonas aerugin...
15926863   1 -----MKALVLGGSgSIGSEIVKQLLTDGFEvYVQYYRTDIN--ELTSKFNd-----dKVRFIQADLSqTIDIDKTFGDI 68  Staphylococcus aure...
16263532     -------------------------------------------------------------------------------- Sinorhizobium meliloti
16800499   1 MDKDIKYAFVTGASgEIGQAICISLAKAGWN-LYLHYHQNKQAVENL-LPLlqAEK-IDVFLIQADFDDVAS----LAEM 73  Listeria innocua
1FMC_A    83 ISKLGk-VDILVNNAGGGGp-KPFDMPM---ADFRRAYELNVFSFFHLSQLVAPEMEKngggVILTITSMAA--ENK-Ni 154 Escherichia coli
15614954  72 LTQCGsaIDVFVHSAG--Qs-VEKLFLDtstSDIMRTFQQHLFSFMELSRGFLPHMLRnrygKIVAVSSVW---GETgAa 145 Bacillus halodurans
16078750  72 TSSIVqpIDAIVLNSG--Rs-HFGLITDvdnATVQEMVQLHVASPYMLTRNLLPGMIRnksgAIVAVSSIW---GETgAs 145 Bacillus subtilis
19553605  95 GQKLKn-LDVVINNVGG-Ti-WAKPYQEyseEEIRKEINRSLFPTLWMCRAALPILIGngggTIVNVSSIAT--GGIn-- 167 Corynebacterium glu...
15843143  79 LAAYGk-ADVLINNAFR-Vp-SMKPLAGttfEHIRDAIELSALGTLRLIQAFTPALAqs-hgAIVNVNSMVI--RHSqPk 152 Mycobacterium tuber...
15597711  72 LERFGr-LDILVNNVGG-Tl-WAKPYQHyaeDEIEAELRRSLLPTLWCCRAALPAMLGqgsgAIVNVSSVAT--RGVn-- 144 Pseudomonas aerugin...
15599357  65 L-SESa-VDALVNNAG--Ia-LPQSLENldlAALQQVFDLNVRVAVQLAQACLPGLKRspagRIVNLCSR----AIHgAr 135 Pseudomonas aerugin...
15926863  69 KS-----LDCLIYASGQSlygVLQDMKD---HDIDACYQLNVLQLIRLCRYFVDVLRQsangRIIVISSIWGetGASmE- 139 Staphylococcus aure...
16263532   1 ------------------------------------------------------------mdGAVSLISA----ASPsAs 16  Sinorhizobium meliloti
16800499  74 EKQVFq-VDAFIHAAG--Hs-HYALFQDttdIETTKLWNVHMFMPMRLIRTFIPKLMKsnqgRIVFISSIW---GEVgAs 146 Listeria innocua
1FMC_A   155 nMTSYASSKAAASHLVRNMAfDL-GEKNIRVNGIAPG-----AILTDALK-SVITPe----IEQkMLQHTP---IRRLGQ 220 Escherichia coli
15614954 146 yEVVYSAAKSGMNGFVKALAkEM-APNGIQVNGVAPG-----AINTSMLS-Sy--------TEEeVLALTEeipAGRLGT 210 Bacillus halodurans
16078750 146 cEVLYSMAKGAQHSFVKGLAkEL-APSGIRVNAVAPG-----AVDTNMMN-Qf--------TPAeKEEIADeipIGRLGR 210 Bacillus subtilis
19553605 168 rV-PYAAAKGGVNGIVSAMArEA-APHNVRVVATAPGgtlapERAVKRGP-GPEGEleekwYQQiVDQTIDsslMKRYGT 244 Corynebacterium glu...
15843143 153 -YGTYKMAKSVLLAMSHSLAtEL-GEQGIRVNSVAPGyi--wGDTLKSYF-DHQAGkygttVDQiYQATAAnsdLKRLPT 227 Mycobacterium tuber...
15597711 145 rV-PYGAAKGGVNALTACLAfET-ADQGIRVNAVAPGgtdapPRRIPRNA-AAQSEeerrwYRQiVEQTLDsslMKRYGS 221 Pseudomonas aerugin...
15599357 136 eRTAYAAAKSALVGVTRTWAlEL-APLGITVNAVAPG-----PIETELFR-QTRPv----gGEEeRRILSTi-pMQRLGR 203 Pseudomonas aerugin...
15926863 140 --TIYSAMKSAQLGFVKALS-QElALTSVTVNAIAPG-----FVAGNMASeWQEDE---------LQAMITelpQQRLVL 202 Staphylococcus aure...
16263532  17 pSELLMRPQRGLVSFTRTWAlEL-AQTGITVNAVAPG-----PTEPN--------------CEGeYQYLTGv-pMHRLGR 75  Sinorhizobium meliloti
16800499 147 mEVVYSTVKGAQIAFCRALSqEL-GPSGITVNAVTPG-----AVETKMMD-Qf--------SANeKEELREeipLKRFAK 211 Listeria innocua
1FMC_A   221 PQDIANAALFLC-SPAASWVSGQILTVSGGG-V 251 Escherichia coli
15614954 211 PMEVAETVAFLC-SERATYIHGHVLSVNGGWyC 242 Bacillus halodurans
16078750 211 TQEIADATAFLL-SEKASYITGQILSVNGGWhC 242 Bacillus subtilis
19553605 245 LEEQVAPICFLA-SEEASYITGSVMPVGGGDqG 276 Corynebacterium glutamicum ATCC 13032
15843143 228 EDEVASAILFLA-SDLASGITGQTLDVNCGEyH 259 Mycobacterium tuberculosis CDC1551
15597711 222 IDEQVAAILFLA-SDEASYITGVTLPVAGGDlG 253 Pseudomonas aeruginosa PA01
15599357 204 PDEVAALIEFLL-SEGASFVTGQVIGVDGGGsL 235 Pseudomonas aeruginosa PA01
15926863 203 PSEVAHTCAYLYhSN-ARSVTGTIQKVNGAWyi 234 Staphylococcus aureus subsp. aureus N315
16263532  76 PDEIAAAIQFLL-SEDAGFITGQTLFVYCGAsI 107 Sinorhizobium meliloti
16800499 212 PEEIAETVEFLI-SKKASYITGEVLRLNGGWlM 243 Listeria innocua
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