Conserved Protein Domain Family
RfaF

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COG0859: RfaF 
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 223928
View PSSM: COG0859
Aligned: 70 rows
Threshold Bit Score: 62.0041
Threshold Setting Gi: 16129924
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15645896  81 KKTLCFIRLD-IIGDYILYRNFLPLFKKYFED----YETTFIGNATIKGIATHCdsQYIDKFIFLDNayWEKYlrigvng 155
gi 15832031   8 RRIAFSYYDY-KAYNFNIEKTDFVVIHIPDQIgdamAIFPVIRALELHKIKHLL--IVTSTINLEVF--NALK------- 75
gi 19704582  48 IKSILFLRYDgKIGDMVVNSLMFREIKKVYPN----IKIGVVARGAAMDIIKDN--PNIDKIYEYHK------------- 108
gi 15645897  17 SQKVFVIRND-KLGDFILAIPALIALKHAFLEkgkeVYLGVVVPSYTTPIALEF--PFIDEVIIED-------------- 79
gi 15603009  32 PRSILFLRQDgKIGDYVVSSFVFREIKKFNPH----IKIGVICTKQNAYLFKQN--PYIDQLYYVKK------------- 92
gi 15603159   1 MQKLLVVRND-KLGDFMLAWPAFAMLKQSNPS----LKLTALVPNYTADLARLC--PYLDDVIIDVG--KKAD------- 64
gi 15640253   1 MKKLLVIRND-KIGDFMLAWPSFAMLKASLPD----CHITALVPKYTAALAELC--PWIDAVIIDPG--QQAD------- 64
gi 15802463   8 RRIAFSYYDY-KAYNFNIEKTDFVVIHIPDQIgdamAIFPVIRALELHKIKHLL--IVTSTINLEVF--NALK------- 75
gi 16129924   8 RRIAFSYYDY-KAYNFNIEKTDFVVIHIPDQIgdamAIFPVIRALELHKIKHLL--IVTSTINLEVF--NALK------- 75
gi 15612269  17 SQKVFVIRND-KLGDFILAIPALIALKHAFLEkgveVYLGVVVPSYTTPIALEF--PFIDEVIIED-------------- 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15645896 156 SRLSKLKELLFFLPKFmrkRYEDVSNLRKESYEICINSsmfYFSTKEDAIIKHliaENKVGVFCTHPIESsfrTDYRKRG 235
gi 15832031  76 --LEQTKLTLVTMTMQ---DHATLKEIKDLAKNITQQYgtpDLCIEAMRKKNL---KTMLFISQLKAKTNfqvVGLTMKC 147
gi 19704582 109 -DRKKIKDLALKIKEE---KYDLLIDFSEMLRVNQMMLi-nLCGARFNIGLN----RKEWKLFDLSIESD---KDFKWTE 176
gi 15645897  80 ------NHLSATLKSK---PIDALIFLFSNFKNARLAFs-lRKSIPYILAPKT---KIYSWLYQKSVRQSrslCLKTEYE 146
gi 15603009  93 KSILDYIKCGLAIQKE---QYDLVIDPTIMIRNRDLLLl-rLINAKHYIGYQK----ANYGLFNINLEG---------QF 155
gi 15603159  65 --KADQLKTLQAIKAV---KFDASINFFSDKYNALLVW---KAGIPFRLAPAT---KLIQFLYNHRVTQRrskSLKPEFE 133
gi 15640253  65 --KAQHKQLVQTVKAQ---QFDASINLFSTMYNALLVW---KARIPYRLAPAT---KLAQIFYQHRIKQKrsqSAKPEYE 133
gi 15802463  76 --LEQTKLTLVTMTMQ---DHATLKEIKDLAKNITQQYgtpDLCIEAMRKKNL---KTMLFISQLKAKTNfqvVGLTMKC 147
gi 16129924  76 --LEQTKLTLVTMTMQ---DHATLKEIKDLAKNITQQYgtpDLCIEGMRKKNL---KTMLFISQLKAKTNfqvVGITMNC 147
gi 15612269  80 ------NHLATTLKNR---SIDALIFLFSNFKNAKLAFs-lRKSIPYILAPKT---KIYSWLYQKRVRQNrslCLKTEYE 146
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15645896 236 EIRKSFYTHLFYPKEVPQFlydsnqdFFQSFFKHFKGVDIGFVELELKLpiaf--eyeKFKNILKPPygVLNLGASDDSR 313
gi 15832031 148 YSPVCKNASRMDQKLRAPVpmtwafmMREAGFPAVRPIYELPLSEDVLDevreemrslGSYIALNLE--GSSQDRTFSLS 225
gi 19704582 177 HITNRYLAYLVKLGLKKENi-----dISYDIYLKDEKKYEFFFNEIKE----------NKKLILNPY--GASKHKSFTIE 239
gi 15645897 147 YNLDLIHAFCKDHNLPNAQlkk--iaWKLKDKSKERSIIASKLNADVG----------LLWIGVHMH--SGGSSPVLPAS 212
gi 15603009 156 HFSELYKLALEKVNITVQD-------ISYDVPFDEQSAVEISEFLQKNQl--------EKYIAINFY--GAARIKKVNDD 218
gi 15603159 134 YNLDLARAFLQKTHCPIVEptppyltFEQNAVQHQREMLSQTLGLALE----------KKWIFVHSG--SGGSATNLSLE 201
gi 15640253 134 YNLDLVRAFLRDIGQPIIEpnapyltFPAEQLAAQRSKLAEQLDIGPD----------KAWLFVHAG--SGGSANNLSLE 201
gi 15802463 148 YSPVCKNASRMDQKLRAPVpmtwafmMREAGFPAVRPIYELPLSEDVLDevreemrslGSYIALNLE--GSSQDRTFSLS 225
gi 16129924 148 FSPLCKNASSMDQKLRAPVpmtwafmMREAGFPAVRPIYELPLSEDVLDevreemrslGSYIAFNLE--GSSQERTFSLS 225
gi 15612269 147 YNLDLIHAFCKDYDLPNAQlkk--iaWKLKDKSKERSIIASKLNANVD----------LLWIGVHMH--SGGSSPVLPAS 212
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15645896 314 VYKRFDEMIYFLNpdYQLVLCGNSk-KDEELANSILKRHKNAIs-LVNQTGLIEYLYLLKNASF--AMGNESSITHLSAC 389
gi 15832031 226 IAENLIEKIQSETdiPIVIVHGPKgeDKARV---LVDCYNnv-yrLSLSPSIKRSAAIIKDAYI--AITPDTSILHMASA 299
gi 19704582 240 TLENIITCLKDKD--IAIILVYFG--DKYKELEFLEKKYNNIYm-PQKIESILDTTILIKKSDY--VISPDTSIVHIASA 312
gi 15645897 213 HFIKLIDCLHNNLscEIILICGPGe-RKATE--ELLKKIPfa-hlYDTSHSLVDLAK--LCANLsvYIGNASGPLHVNAL 286
gi 15603009 219 NIKKYLDYLTQVSggKKLVLLSYP--EVTEKLTQLSADYPHIF--VHPTTKIFHTIELIrHCDQ--LISTDTSTVHIASG 292
gi 15603159 202 QYAQLILGLLSQFdcQIVLTAGPNesEKAHSLANLVNHHnv--vvYDKNAGLVDFARSLACADL--FIAGSTGPLHLSAA 277
gi 15640253 202 QYCELVTGVMDEHk-QVVLTAGPGeeEKAAQLQSLLAEQGVlaalYAKNDGLVDFTRSLACAQL--FIAGSTGPLHIAAA 278
gi 15802463 226 IAENLIEKIQSETdiPIVIVHGPKgeDKARV---LVDCYNnv-yrLSLSPSIKRSAAIIKDAYI--AITPDTSILHMASA 299
gi 16129924 226 IAENLIAKI----------------------------------------------------------------------- 234
gi 15612269 213 HFIELIAILHEKLscEIILICGPGe-RKATE--ELLKEVPfa-hlYDTSHSLVDLAK--LCANLsvCIGNASGPLHVNAL 286
                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15645896 390 LKIPYAFIVSSGLSSPrfhPyPKEVGPNIHMIYPRDFQKIISrssdwmfkamtMPHPPVDFVNPQDIISAIKRFAPHLL 468
gi 15832031 300 YNTPVVAIYADYKT---------RWPAMADVSESVVVGQKID---------------NISLDEFAKALKSVLARI---- 350
gi 19704582 313 LNKKMITVYPPNGGKY---GvDHLVWAPKSEYSRVIFCKDKTg---------tYDEIDINTFNFDEIKEEILKLINNSD 379
gi 15645897 287 FDNQSIGFYPNELSAS---I--ARWRPFN--ERFLGITPPNG-------------SNDMGLIDIEKEGEKIVGFINYRK 345
gi 15603009 293 FNKPIIGIYKEDPIAF-------THWQPKSQAETHILFYKEN----------------INELSPEQIDPAWLVR----- 343
gi 15603159 278 LNIPTIGFYPSRRSAT---P--LRWQPINDPTKHLAFSPQTQd---------rEKQMDLSLIDIDQVLTQAIPFVKTMW 342
gi 15640253 279 LDVPTVGFFPAKRSAT---P--LRWRPLNSQGKHIAFCPPPAdd--------kANQENMGRIDMKSVLTELAPWLRSVQ 344
gi 15802463 300 YNTPVVAIYADYKT---------RWPAMADVSESVVXGQKID---------------NISLDEFAKALKSVLARI---- 350
gi 16129924     -------------------------------------------------------------------------------
gi 15612269 287 FDNQSIGFYPNELTAS---I--ARWRPFN--EQFLGITPPNG-------------SNDMGLIDIQKESEKIMGFITKNL 345
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