Conserved Protein Domain Family
HisM

?
COG0765: HisM 
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]
Statistics
?
PSSM-Id: 223836
View PSSM: COG0765
Aligned: 190 rows
Threshold Bit Score: 141.873
Threshold Setting Gi: 15645784
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16264848 148 FALTLLGFMlffgagkastpesimrrlgalsiglvssggllFILFfAHIAFAAGVATTVRAAIAAYLLAAIIGliwvgll 227
gi 16079798   1 -------------------------------------mnvsILFD-NFSMYMDGFYHTLLASVIALAGSFVLG------- 35
gi 16079799   1 -----------------------------------mdfigaYSQE-HLAFLWDGFLVTLYVAFISIILSFFFG------- 37
gi 15792248   1 -------------------------------------menvFNAQ-NIEFLMQGLFLTLKIALATCIISIVFG------- 35
gi 15792249  14 ILTSWGLYDensispf-------------------avwkflDALD-NKDAFINGFIYTLEVSILALLIATIFG------- 66
gi 15645784   1 -------------------------------------mgvlLELD-NLKRLLEGFETTLLIALSSAMISIIVG------- 35
gi 15900515   1 ----------------------------------mesilevLTPD-NLVFIFKGFGLTLYISLIAIILSTIIG------- 38
gi 15900516   3 DLSSWTAYf-------------------------------qDFG-----QFFNGFLFTLALAVGSFILAMVLG------- 39
gi 15900608   1 --------------------------------mqdsgiqvlFQGN-NLLRILQGLGVTIGISILSVLLSMMFR------- 40
gi 15612162   1 -------------------------------------mgvlLELD-NLKRLLEGFETTLLIALSSAIISIVVG------- 35
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16264848 228 qlhytartsIIFALATLGLTlvaawfllqprtaYVLAGRLDGTVAIVSNTPsgligavrfgqypgapgeeaavrtflgpa 307
gi 16079798  36 ---------VAVAVMRITVF-------------KPLQWLGTAYVEFIRNIP----------------------------- 64
gi 16079799  38 ---------LIAGTLRYAKV-------------PVLSQLIAVLVETIRNLP----------------------------- 66
gi 15792248  36 ---------TFLAITKNYGD-------------RLSKFLAACYIDIFRNTP----------------------------- 64
gi 15792249  67 ---------TIGGVMATSRF-------------KIIRAYTRIYVELFQNVP----------------------------- 95
gi 15645784  36 ---------MLLGSLMAFGS-------------QIVVLACRVYLESIRIIP----------------------------- 64
gi 15900515  39 ---------TVLAVTRNGKN-------------PVLRIISSIYIEFVRNVP----------------------------- 67
gi 15900516  40 ---------IFFGAMSTSKR-------------PILRILARIFVEFYQNTP----------------------------- 68
gi 15900608  41 ---------TVMGIIMTSHS-------------RIIRFLTRLYLEFIRIMP----------------------------- 69
gi 15612162  36 ---------MLLGSLMAFGS-------------KIMVLACRVYLESIRIIP----------------------------- 64
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16264848 308 eavaameknevtaallpsaavpgglpllwetaalndrdraagitfaVLAIILGLlTFGGylhrrhPLAIGsefvvdtirg 387
gi 16079798  65 ----------------------------------------------LLLITFVF-YFG-------LPNAG---------- 80
gi 16079799  67 ----------------------------------------------LLLIIFFT-FFA-------LPEIG---------- 82
gi 15792248  65 ----------------------------------------------LLLWMLAA-CFVL------PVFFG---------- 81
gi 15792249  96 ----------------------------------------------LVIQIFFL-FYAL------PVLG----------- 111
gi 15645784  65 ----------------------------------------------LLAWLFIV-YFGL------ASWFD---------- 81
gi 15900515  68 ----------------------------------------------NLLWIFTI-FLV---------------------- 78
gi 15900516  69 ----------------------------------------------LLVQFVIV-FYGL------PLISDh--------- 86
gi 15900608  70 ----------------------------------------------QLVLLFIV-YFGL------ARNFN---------- 86
gi 15612162  65 ----------------------------------------------LLAWLFIV-YFGL------ASWFD---------- 81
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16264848 388 ipmlvivlyVGLPLsgalkdatqgvldppnLMRGIVAMALAYSAYLAEIFRSGINAIPIGQIEAARSIGLNRWQTARLVV 467
gi 16079798  81 ---------LRLDG----------------FQAGTVALTIYTSAFIAEAIRAGIQSVSKGQMEAARSSGFTYSQAMLHII 135
gi 16079799  83 ---------IKLEI----------------TAAAITALTIFESAMLSEIIRSGLKSIDKGQIEAARSSGLSYTQTLFFIV 137
gi 15792248  82 ----------QFPQ----------------AFWGTIGFSLYTSSVMAEIIRGGLNSIPKGQFEAAYSQGFGKFFTLFYII 135
gi 15792249 112 ----------IRLDi---------------FTIGVLGVGAYHGAYVSEVVRSGILAVPRGQFEASASQGFTYIQQMRYII 166
gi 15645784  82 ---------LHISA----------------VLASVIVFSLWGGAEMMDLTRGVLTSVSKHQIESALALGLDSKKVIFNII 136
gi 15900515  79 ---------FKMKS----------------TPAGITAFTLFTSAALAEIIRGGLNAVDKGQYEAGMSQGFTSAQILYYII 133
gi 15900516  87 ---------IIMIPi---------------YWTAVLCVGLYHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLII 142
gi 15900608  87 ---------INISG----------------ETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHII 141
gi 15612162  82 ---------LHISA----------------VLASVIVFSLWGGAEMMDLTRGVLTSVSKHQVESALALGLDSKKVIFNVI 136
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16264848 468 LPQAFRIIIPPLGNELIAILKDTS-LLSILSIRDITQRMREFQSASF-----LPFAPYNSAAIFYIFLTLAAASLINMIE 541
gi 16079798 136 LPQAIKIVIPPLGNQFLNLVKNSS-ILGVVAGLDLMYQADLVSSSTL-----VVFDVYIFVALFYLVLTIPLSIGVNYLE 209
gi 16079799 138 MPQALRRMVPPIVSQFISLLKDTS-LAVVIALPELIHNAQIINGQSAdg--sYFFPIFLLAALMYFAVNYSLSLAARRLE 214
gi 15792248 136 LPQTFRKIIPALLSQIVTTVKDTA-YLAGLGIAELTYNSKTILAKLTsf--eEILAMIGVVAGIYFIICFSLSMLVRYYA 212
gi 15792249 167 VPQTIRIILPPMTNQMVNLIKNTS-VLLIVGGAELMHSADSYAADYG-----NYAPAYIFAAVLYFIICYPLAYFAKAYE 240
gi 15645784 137 FPQSFLSLLPSSLNLFTRMIKTTA-LVSLIGAIDLLKVGQQIIELNLlrmpnASFVVYGVILMFYFSLCYSLSLYSSYLE 215
gi 15900515 134 LPQAIRKMLPAIISQFVTVIKDTSlLYSVIALQELFGASQILMGRYFep--eQVFSLYILIALIYFSFNLAISSLSHMLA 211
gi 15900516 143 LPQAFRIILPPLTNQIVNLIKNTS-TVAIISGVDLMFVTKSWSALNG-----NYIPAFLGAALLYFALCFPVAQFGRKME 216
gi 15900608 142 IPQVLRRLLPQAINLVTRMIKTTS-LVVLIGVVEVTKVGQQIIDSNRltiptASFWIYGTILILYFAVCYPISKLSTHLE 220
gi 15612162 137 FPQSFLSLLPSSLNLFTRMIKTTA-LVSLIGAVDLLKVGQQIIELNLlrmpnASFVVYGVILMFYFTLCYSLSLYSSYLE 215

                ....*..
gi 16264848 542 RKYDIKH 548
gi 16079798 210 KRLEKSY 216
gi 16079799 215 VRQT--- 218
gi 15792248 213 KKTAYIS 219
gi 15792249 241 NKLKKah 247
gi 15645784 216 KKFQHir 222
gi 15900515 212 KRWQQAA 218
gi 15900516 217 QANKKay 223
gi 15900608 221 KHWRN-- 225
gi 15612162 216 KKFQYir 222
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap