1F0K_A 7 KRLMVMAGGTGGHVFPGLAVAHHLMAQGW---QVRWLGTADRMEADLVPKH-GIEIDFIRISGLRGKGIKA-LIAAP--- 78 Escherichia coli 15614520 4 GPLIFSASIGNGHNQAAKALQVEFQNKGY---QPEIIDTFYSLSPALHKFMlTSYVNLLKVGPRIWQKIYFqAEKYP--- 77 Bacillus halodurans 16078400 4 ILIFPFLSISTGHHHVADALQAELESQGLaaeKIDIFSHSYRRLEKLSSVAyLKWIQYFPKTYSGIYRLLAcGEFQHdkr 83 Bacillus subtilis 1730908 6 RVLILTANYGNGHVQVAKTLYEQCVRLGFqhvTVSNLYQESNPIVSEVTQYlYLKSFSIGKQFYRLFYYGVdKIYNKrk- 84 Bacillus subtilis 15896150 2 KFLILSVSAGGGHIHAAFALKKYIAKYLEg-sQVKMLDTIKYLNPFLDKVLiGGYLKTLKVSPALFGKLYNfTEKDDnla 80 Clostridium acetobu... 15806096 29 RALFMSVSLGAGHDQAQQAVKQAFAERGVellGAEHDSVEYLSTFERSFTVdLYEFELRYAPWLYRGFYWLtDQDQPwni 108 Deinococcus radiodu... 20091013 1 MDVVLVILLKNTGLVKKMKICLTCSHGG------HLTEILQLMDAFEGNDIfFITYEGARSSELTRKYTMKnLGKKP--- 71 Methanosarcina acet... 20093810 1 -MHVLIASGDGGHLTRALALAEELSDRGHd-vTFAVNEDSDQAVERLKKAG---FEEYVGLPRPRRMGDTS--WKAA--- 70 Methanopyrus kandle... 15899226 1 MTRILIIASGGGHTGFARAIAQYLPEKVD-----FVIPTNDPYSRQMISQY-ANKIYEIPKGREPDESSLV--L------ 66 Sulfolobus solfatar... 17229779 1 -MKVLLICSSGGHFKGLQQLQPFWENHER----VWVTFKTATTQAALTEEK-------VYWAYSPTNRNLP---N----- 60 Nostoc sp. PCC 7120 15614520 4 GPLIFSASIGNGHNQAAKALQVEFQNKGY---QPEIIDTFYSLSPALHKFMlTSYVNLLKVGPRIWQKIYFqAEKYP--- 77 Bacillus halodurans 16078400 4 ILIFPFLSISTGHHHVADALQAELESQGLaaeKIDIFSHSYRRLEKLSSVAyLKWIQYFPKTYSGIYRLLAcGEFQHdkr 83 Bacillus subtilis 1730908 6 RVLILTANYGNGHVQVAKTLYEQCVRLGFqhvTVSNLYQESNPIVSEVTQYlYLKSFSIGKQFYRLFYYGVdKIYNKrk- 84 Bacillus subtilis 15896150 2 KFLILSVSAGGGHIHAAFALKKYIAKYLEg-sQVKMLDTIKYLNPFLDKVLiGGYLKTLKVSPALFGKLYNfTEKDDnla 80 Clostridium acetobu... 15806096 29 RALFMSVSLGAGHDQAQQAVKQAFAERGVellGAEHDSVEYLSTFERSFTVdLYEFELRYAPWLYRGFYWLtDQDQPwni 108 Deinococcus radiodu... 20091013 1 MDVVLVILLKNTGLVKKMKICLTCSHGG------HLTEILQLMDAFEGNDIfFITYEGARSSELTRKYTMKnLGKKP--- 71 Methanosarcina acet... 20093810 1 -MHVLIASGDGGHLTRALALAEELSDRGHd-vTFAVNEDSDQAVERLKKAG---FEEYVGLPRPRRMGDTS--WKAA--- 70 Methanopyrus kandle... 15899226 1 MTRILIIASGGGHTGFARAIAQYLPEKVD-----FVIPTNDPYSRQMISQY-ANKIYEIPKGREPDESSLV--L------ 66 Sulfolobus solfatar... 17229779 1 -MKVLLICSSGGHFKGLQQLQPFWENHER----VWVTFKTATTQAALTEEK-------VYWAYSPTNRNLP---N----- 60 Nostoc sp. PCC 7120
1F0K_A 79 ----LRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLG--------IPVVLHEQNGIAGLTNKWLAKIATKVM 146 Escherichia coli 15614520 78 ----LFLFLDQFATFFVESLHATVKSNRCSFLVSTHPFVTAFLVRlkskkqlnLPLYTVITDFVLHPAYLRPEIDGYFTS 153 Bacillus halodurans 16078400 84 --yfMYECVFTQQMRHILQEKQPDIAFCTHALPSYLLNRLKPEYPn-------LTVVNVYTDFFVNQLWGRKNIDYHFVP 154 Bacillus subtilis 1730908 85 --fnIYFKMGNKRLGELVDEHQPDIIINTFPMIVVPEYRRRTGRV--------IPTFNVMTDFCLHKIWVHENVDKYYVA 154 Bacillus subtilis 15896150 81 slsnKINEFMAYKLIPIIEDFNPDVIICTHPFPTEMVSILKSKESl------kTPMLCILTDYAPHSFWIRPQVNSYVVS 154 Clostridium acetobu... 15806096 109 -isrMFTWLGMGAFKDELRELRPEVVINSFWAPAAVCDTLRAQTGq------rFLNCLIVTDYRAHLHWARRETDLLMVA 181 Deinococcus radiodu... 20091013 72 ----LRFLLSVPKVFGILLREKPDIIISTGSEIAIPVFYAAKVLRik-----tMFIESLCRVEEPSLTGKILYPVSDVFL 142 Methanosarcina acet... 20093810 71 ----LGGLKNYLAASKVLRDVRPDLILSTGAGVAIGPMIAGKFKR--------LPVAHYEPTDVVSVSGKVAKLCADIIG 138 Methanopyrus kandle... 15899226 67 ----FKRLFSIIVKSASIKKYDLIIATG-SNHSIFPSFFQFLKGGk------vYGIESQDRLITKGKAIGIISNYAKGVF 135 Sulfolobus solfatar... 17229779 61 ------LFRNLLLAFQVISKTKPDLILSTGAGVAVPFLILGKLFGsq-----tVFVESVTRIITLSLSARLVLPFLSVLY 129 Nostoc sp. PCC 7120 15614520 78 ----LFLFLDQFATFFVESLHATVKSNRCSFLVSTHPFVTAFLVRlkskkqlnLPLYTVITDFVLHPAYLRPEIDGYFTS 153 Bacillus halodurans 16078400 84 --yfMYECVFTQQMRHILQEKQPDIAFCTHALPSYLLNRLKPEYPn-------LTVVNVYTDFFVNQLWGRKNIDYHFVP 154 Bacillus subtilis 1730908 85 --fnIYFKMGNKRLGELVDEHQPDIIINTFPMIVVPEYRRRTGRV--------IPTFNVMTDFCLHKIWVHENVDKYYVA 154 Bacillus subtilis 15896150 81 slsnKINEFMAYKLIPIIEDFNPDVIICTHPFPTEMVSILKSKESl------kTPMLCILTDYAPHSFWIRPQVNSYVVS 154 Clostridium acetobu... 15806096 109 -isrMFTWLGMGAFKDELRELRPEVVINSFWAPAAVCDTLRAQTGq------rFLNCLIVTDYRAHLHWARRETDLLMVA 181 Deinococcus radiodu... 20091013 72 ----LRFLLSVPKVFGILLREKPDIIISTGSEIAIPVFYAAKVLRik-----tMFIESLCRVEEPSLTGKILYPVSDVFL 142 Methanosarcina acet... 20093810 71 ----LGGLKNYLAASKVLRDVRPDLILSTGAGVAIGPMIAGKFKR--------LPVAHYEPTDVVSVSGKVAKLCADIIG 138 Methanopyrus kandle... 15899226 67 ----FKRLFSIIVKSASIKKYDLIIATG-SNHSIFPSFFQFLKGGk------vYGIESQDRLITKGKAIGIISNYAKGVF 135 Sulfolobus solfatar... 17229779 61 ------LFRNLLLAFQVISKTKPDLILSTGAGVAVPFLILGKLFGsq-----tVFVESVTRIITLSLSARLVLPFLSVLY 129 Nostoc sp. PCC 7120
1F0K_A 147 QAFP-----GAFPN---AEVVGNPVRTDVLA-LPLPQQRLAGRE--------GPVRVLVVGGSQGARI-LNQTMPQVAAK 208 Escherichia coli 15614520 154 DPNFtdfakLNNVSddrFFPTGIPIPNLESIdQPKWKVRNDLGLd------pQRKVLIIAGGGIGLTN-YAQVIRALECL 226 Bacillus halodurans 16078400 155 STEVkkqliSEGIDqnnIYLTGIPVHQNFEMeSADTLQHHP------------PYTIIITGGSMGVGG-ILKWVQELSPG 221 Bacillus subtilis 1730908 155 TDYVkekllEIGTHpsnVKITGIPIRPQFEEsMPVGPIYKKYNLs------pNKKVLLIMAGAHGVLK-NVKELCENLVK 227 Bacillus subtilis 15896150 155 NSDMvdemvRRGVNrenIYDLGIPVDPDFIRnFDKIETLNELNLs------lNKKTILIMGGSLGIGK-IEDIYEALSKS 227 Clostridium acetobu... 15806096 182 SEETrrqmlERGVRpeqVEVTGIPISPAFREvLAADRWALRAELfsemslrpGVPLLLLSGGGRGHYAaAADVLTELGNL 261 Deinococcus radiodu... 20091013 143 VQWK-----QLLFK----FGRKAQYWGNVL-------------------------------------------------- 163 Methanosarcina acet... 20093810 139 VWDEd---mAEYYGd-rVINVGIVLPRSFEEaDPEEAREKYDLG--------DRVLVWTTGSAGYKPA-LEGLVRCAEEG 205 Methanopyrus kandle... 15899226 136 LHWQ-----EQRK----LYEKKGIVVGPIVE--KPKYESKD------------EGYILVTTGSMGFKR-LFDAIVKSVIG 191 Sulfolobus solfatar... 17229779 130 VQWP-------------QLQTLYPQAELIVP--QESL------------------------------------------- 151 Nostoc sp. PCC 7120 15614520 154 DPNFtdfakLNNVSddrFFPTGIPIPNLESIdQPKWKVRNDLGLd------pQRKVLIIAGGGIGLTN-YAQVIRALECL 226 Bacillus halodurans 16078400 155 STEVkkqliSEGIDqnnIYLTGIPVHQNFEMeSADTLQHHP------------PYTIIITGGSMGVGG-ILKWVQELSPG 221 Bacillus subtilis 1730908 155 TDYVkekllEIGTHpsnVKITGIPIRPQFEEsMPVGPIYKKYNLs------pNKKVLLIMAGAHGVLK-NVKELCENLVK 227 Bacillus subtilis 15896150 155 NSDMvdemvRRGVNrenIYDLGIPVDPDFIRnFDKIETLNELNLs------lNKKTILIMGGSLGIGK-IEDIYEALSKS 227 Clostridium acetobu... 15806096 182 SEETrrqmlERGVRpeqVEVTGIPISPAFREvLAADRWALRAELfsemslrpGVPLLLLSGGGRGHYAaAADVLTELGNL 261 Deinococcus radiodu... 20091013 143 VQWK-----QLLFK----FGRKAQYWGNVL-------------------------------------------------- 163 Methanosarcina acet... 20093810 139 VWDEd---mAEYYGd-rVINVGIVLPRSFEEaDPEEAREKYDLG--------DRVLVWTTGSAGYKPA-LEGLVRCAEEG 205 Methanopyrus kandle... 15899226 136 LHWQ-----EQRK----LYEKKGIVVGPIVE--KPKYESKD------------EGYILVTTGSMGFKR-LFDAIVKSVIG 191 Sulfolobus solfatar... 17229779 130 VQWP-------------QLQTLYPQAELIVP--QESL------------------------------------------- 151 Nostoc sp. PCC 7120
1F0K_A 209 LGdSVTIWHQSGKGS-QQSVEQAYAEAGQpqHKVTEFIDD---MAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQH 284 Escherichia coli 15614520 227 PEp-IQLLCMIGHNYqVKEKISRIKSKHe--LKVIEFTDK---FLLYLKASDAILSKAGGLTMAESLVCETPIIIHQPVP 300 Bacillus halodurans 16078400 222 GK--ILYKILCGRNEkLYSYVKSLHHPl---IEAIPYLHSkaeMNRLYEQATGIMTKPGGVTISECLQKRLPVFIYHALP 296 Bacillus subtilis 1730908 228 DD-QVQVVVVCGKNTaLKESLSALEAENGdkLKVLGYVER---IDELFRITDCMITKPGGITLTEATAIGVPVILYKPVP 303 Bacillus subtilis 15896150 228 RAn-IQIIIITGNNKkLYSKLLELAEDSYveTRILGYTRD---VNRYMQASDLLLTKPGGLTITEALICRVPLAVFSPIP 303 Clostridium acetobu... 15806096 262 GR-AVQVLVPASRQG--EGTETIGG-AT---VHHLGFRRD---LPRLLAASDLVVGKAGGLTVAEATALGVPLVIYAPIP 331 Deinococcus radiodu... 20091013 -------------------------------------------------------------------------------- Methanosarcina acet... 20093810 206 LLrDWEVVVNTGNAMdPKRLKRALNGLCSg-IVVKRFFHD---FPALLKAADLVVCLGG-ATPVEAAALGKPVVVLPRRD 280 Methanopyrus kandle... 15899226 192 KR---IVIQTGKIDP---TIYRNQN------VTTFSFDPD---LEKWIANASLVITHQGKTAMEAVVMYRKPVIMVYNND 256 Sulfolobus solfatar... 17229779 -------------------------------------------------------------------------------- Nostoc sp. PCC 7120 15614520 227 PEp-IQLLCMIGHNYqVKEKISRIKSKHe--LKVIEFTDK---FLLYLKASDAILSKAGGLTMAESLVCETPIIIHQPVP 300 Bacillus halodurans 16078400 222 GK--ILYKILCGRNEkLYSYVKSLHHPl---IEAIPYLHSkaeMNRLYEQATGIMTKPGGVTISECLQKRLPVFIYHALP 296 Bacillus subtilis 1730908 228 DD-QVQVVVVCGKNTaLKESLSALEAENGdkLKVLGYVER---IDELFRITDCMITKPGGITLTEATAIGVPVILYKPVP 303 Bacillus subtilis 15896150 228 RAn-IQIIIITGNNKkLYSKLLELAEDSYveTRILGYTRD---VNRYMQASDLLLTKPGGLTITEALICRVPLAVFSPIP 303 Clostridium acetobu... 15806096 262 GR-AVQVLVPASRQG--EGTETIGG-AT---VHHLGFRRD---LPRLLAASDLVVGKAGGLTVAEATALGVPLVIYAPIP 331 Deinococcus radiodu... 20091013 -------------------------------------------------------------------------------- Methanosarcina acet... 20093810 206 LLrDWEVVVNTGNAMdPKRLKRALNGLCSg-IVVKRFFHD---FPALLKAADLVVCLGG-ATPVEAAALGKPVVVLPRRD 280 Methanopyrus kandle... 15899226 192 KR---IVIQTGKIDP---TIYRNQN------VTTFSFDPD---LEKWIANASLVITHQGKTAMEAVVMYRKPVIMVYNND 256 Sulfolobus solfatar... 17229779 -------------------------------------------------------------------------------- Nostoc sp. PCC 7120
1F0K_A 285 K-DRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSR------ETLLTMAERARAASIPDATERVANEVSRVARA 356 Escherichia coli 15614520 301 G---HEEHNAKFLIDAGAALRVKGSK----EIPTTIKRVLYe----eACFGPMIENARKLKKPNAANEIVEQMLLLVKE 368 Bacillus halodurans 16078400 297 G---QEEMNLNLLHERKLVTDMRNWD--MQKAEEYIAAFFQs----nEQMKEYKKHVNGYLGEMSDRKIKDVLKRIIWK 366 Bacillus subtilis 1730908 304 G--QEKE-NANFFEDRGAAIVVNRHEEILESVTSLLADEDTlhrmkkNIKDLHLANSSEVILEDILKESEMMTAKQKAK 379 Bacillus subtilis 15896150 304 G---QEEKNEDFLLKHNLAISIRDSE----NCLGIIESLISn----pELLQAMKDNCNKFSKPSSGKDICNLLINLINK 371 Clostridium acetobut... 15806096 332 G---QEEHNADFLERHGAGLWARARH----DVRPLVLRALDp-----AEHARLSAGARAVGIPDAADRVAGAILRRLGD 398 Deinococcus radiodurans 20091013 ------------------------------------------------------------------------------- Methanosarcina aceti... 20093810 281 VlRDHQYVTAKKLEKRGVAVAAEDAS-NPEEVVKAVSRALSid---pEDLKRMGERGKELFGGNARERFIDLCEELVAS 355 Methanopyrus kandler... 15899226 257 WkSATTLSDAKKYAEILGATFLSDPI-TWSDYNVLLEAIEN--------ANEP--NVFDTGTPNLVKHVLSEL------ 318 Sulfolobus solfataricus 17229779 ------------------------------------------------------------------------------- Nostoc sp. PCC 7120 15614520 301 G---HEEHNAKFLIDAGAALRVKGSK----EIPTTIKRVLYe----eACFGPMIENARKLKKPNAANEIVEQMLLLVKE 368 Bacillus halodurans 16078400 297 G---QEEMNLNLLHERKLVTDMRNWD--MQKAEEYIAAFFQs----nEQMKEYKKHVNGYLGEMSDRKIKDVLKRIIWK 366 Bacillus subtilis 1730908 304 G--QEKE-NANFFEDRGAAIVVNRHEEILESVTSLLADEDTlhrmkkNIKDLHLANSSEVILEDILKESEMMTAKQKAK 379 Bacillus subtilis 15896150 304 G---QEEKNEDFLLKHNLAISIRDSE----NCLGIIESLISn----pELLQAMKDNCNKFSKPSSGKDICNLLINLINK 371 Clostridium acetobut... 15806096 332 G---QEEHNADFLERHGAGLWARARH----DVRPLVLRALDp-----AEHARLSAGARAVGIPDAADRVAGAILRRLGD 398 Deinococcus radiodurans 20091013 ------------------------------------------------------------------------------- Methanosarcina aceti... 20093810 281 VlRDHQYVTAKKLEKRGVAVAAEDAS-NPEEVVKAVSRALSid---pEDLKRMGERGKELFGGNARERFIDLCEELVAS 355 Methanopyrus kandler... 15899226 257 WkSATTLSDAKKYAEILGATFLSDPI-TWSDYNVLLEAIEN--------ANEP--NVFDTGTPNLVKHVLSEL------ 318 Sulfolobus solfataricus 17229779 ------------------------------------------------------------------------------- Nostoc sp. PCC 7120
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",