1BSV,1EQ2,1BWS,1E6U


Conserved Protein Domain Family
WcaG

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COG0451: WcaG 
Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
linked to 3D-structure
Statistics
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PSSM-Id: 223528
Aligned: 289 rows
Threshold Bit Score: 58.8002
Threshold Setting Gi: 15609005
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1BSV_A     4 QR--VFIAGH----RGMVG-------SAIRRQLEQ-----RGDVELVLRTRD--------------ELNLLDSrAVHDFF 51  Escherichia coli
15793975   7 PH--ISITG-----LGYLG-------LPLAQKfy----qhGSRVAAIKRSLTsddinlp-ihldtfDLG-STD-AFQTA- 64  Neisseria meningiti...
15676707   7 PH--ISITG-----LGYLG-------LPLAQKfy----qhGSRVAAVKRSLTsddinlp-ihldtiDLN-QDS-AFQSAN 65  Neisseria meningiti...
15596756     --------------------------------------------------------------------------------     Pseudomonas aerugin...
15596757     --------------------------------------------------------------------------------     Pseudomonas aerugin...
15602679   2 KS--VSIVG-----LGWLG-------LPLARHlk----nlGWEVKGSKRTHEgaeqmrl-vrleayPLE-LTP-EINADp 60  Pasteurella multocida
13541188   1 --mkAIVFGg----SGFIG-------SHIVNsl-----eaDSVAYYSLEKGTnvkrnda---vwiqgdV-TDY-SKVEA- 56  Thermoplasma volcanium
16082244   5 KHvkVIVFGg----SGFLG-------SHLVNrl-----daDEMVYFSLEKGNsvtrkda---kwvsgdV-TDY-SKVAE- 62  Thermoplasma acidop...
15641701   1 --mkRVVVIG----AGWLG-------LPLAQWLKQq----GHIVYATRTTPQavqtledqgiesfvCQLDQPd-GLSDAL 62  Vibrio cholerae
16121830  73 INinHVLLGDlaepDSFINdvriddvTHVINCAAIasfgnNPLIWKVNVEGTlafgkr----maqvagL-QRF-VHVGT- 145 Yersinia pestis
15793975   7 PH--ISITG-----LGYLG-------LPLAQKfy----qhGSRVAAIKRSLTsddinlp-ihldtfDLG-STD-AFQTA- 64  Neisseria meningiti...
15676707   7 PH--ISITG-----LGYLG-------LPLAQKfy----qhGSRVAAVKRSLTsddinlp-ihldtiDLN-QDS-AFQSAN 65  Neisseria meningiti...
15596756     --------------------------------------------------------------------------------     Pseudomonas aerugin...
15596757     --------------------------------------------------------------------------------     Pseudomonas aerugin...
15602679   2 KS--VSIVG-----LGWLG-------LPLARHlk----nlGWEVKGSKRTHEgaeqmrl-vrleayPLE-LTP-EINADp 60  Pasteurella multocida
13541188   1 --mkAIVFGg----SGFIG-------SHIVNsl-----eaDSVAYYSLEKGTnvkrnda---vwiqgdV-TDY-SKVEA- 56  Thermoplasma volcanium
16082244   5 KHvkVIVFGg----SGFLG-------SHLVNrl-----daDEMVYFSLEKGNsvtrkda---kwvsgdV-TDY-SKVAE- 62  Thermoplasma acidop...
15641701   1 --mkRVVVIG----AGWLG-------LPLAQWLKQq----GHIVYATRTTPQavqtledqgiesfvCQLDQPd-GLSDAL 62  Vibrio cholerae
16121830  73 INinHVLLGDlaepDSFINdvriddvTHVINCAAIasfgnNPLIWKVNVEGTlafgkr----maqvagL-QRF-VHVGT- 145 Yersinia pestis
1BSV_A    52 ASERI-DQVYLAAAKVGGIVANNT--YpAdFIYQNMMIESNIIHAAHQ-NDVNKLLF-LGS-SCIYPKlaKQPMAESELl 125 Escherichia coli
15793975  65 ------LWRHHADKPVWFFLLPPS------SLTHYADTVKQWAELARA-CNVQHLIF-TSStS-VYGD--TAR-ECDETa 126 Neisseria meningiti...
15676707  66 LARDtsFWRHHANKPVWFCLLPPS------SLTHYADTVKQWAELARA-CNVQHLIF-TSStS-VYGD--TAR-ECDEIa 133 Neisseria meningiti...
15596756   1 -------MNMHADGEQITAIDTR--------ERILLTGATGFLGGSVA----AQLIA-AGHgANLSFL------VRAES- 53  Pseudomonas aerugin...
15596757     --------------------------------------------------------------------------------     Pseudomonas aerugin...
15602679  61 -----dDLTLLLSVDSLVINIPPSqyF-F-DPQHYVQGIQHLVNEALL-HGVSHLIF-ISStS-VFPE--HSG-YFDESc 127 Pasteurella multocida
13541188  57 ------SMAGYDTVFFAVEDWAADe-A-R-NREILLNGIKNVVSAIKK-ASTDQKLV-SFS----MIN--QPSY---P-- 114 Thermoplasma volcanium
16082244  63 ------AMKDVDVAIFAVEDWNADe-K-R-NREILLDGIKNVVNAVKA-NNTEQKVV-SFS----IIN--HPSY---P-- 120 Thermoplasma acidop...
15641701  63 LERQC-DTVIGCFPPGFRQGAG----------EHYAKHWQNLVQHAKQaNIQKLVMIsSTSvYPDIAK------AMNEQ- 124 Vibrio cholerae
16121830 146 ------AMACTPEADTVVDERVLSteN-D-AHLVEYTKSKSAIECLLA-EHCPTLPL-VFArPSIVVG--HTRLGCQPSs 213 Yersinia pestis
15793975  65 ------LWRHHADKPVWFFLLPPS------SLTHYADTVKQWAELARA-CNVQHLIF-TSStS-VYGD--TAR-ECDETa 126 Neisseria meningiti...
15676707  66 LARDtsFWRHHANKPVWFCLLPPS------SLTHYADTVKQWAELARA-CNVQHLIF-TSStS-VYGD--TAR-ECDEIa 133 Neisseria meningiti...
15596756   1 -------MNMHADGEQITAIDTR--------ERILLTGATGFLGGSVA----AQLIA-AGHgANLSFL------VRAES- 53  Pseudomonas aerugin...
15596757     --------------------------------------------------------------------------------     Pseudomonas aerugin...
15602679  61 -----dDLTLLLSVDSLVINIPPSqyF-F-DPQHYVQGIQHLVNEALL-HGVSHLIF-ISStS-VFPE--HSG-YFDESc 127 Pasteurella multocida
13541188  57 ------SMAGYDTVFFAVEDWAADe-A-R-NREILLNGIKNVVSAIKK-ASTDQKLV-SFS----MIN--QPSY---P-- 114 Thermoplasma volcanium
16082244  63 ------AMKDVDVAIFAVEDWNADe-K-R-NREILLDGIKNVVNAVKA-NNTEQKVV-SFS----IIN--HPSY---P-- 120 Thermoplasma acidop...
15641701  63 LERQC-DTVIGCFPPGFRQGAG----------EHYAKHWQNLVQHAKQaNIQKLVMIsSTSvYPDIAK------AMNEQ- 124 Vibrio cholerae
16121830 146 ------AMACTPEADTVVDERVLSteN-D-AHLVEYTKSKSAIECLLA-EHCPTLPL-VFArPSIVVG--HTRLGCQPSs 213 Yersinia pestis
1BSV_A   126 qGTLEPTNe------PYAIAKIAGIKLCESYNrqyGRDYRSVMPT-NLYGPHDNFHpSNSHVIPA--LLRRFHEATAqna 196 Escherichia coli
15793975 127 tPDPQTE---------SARQILAAEQHLLDSGi---SNIDILRLG-GLYCAERHPV-SRLVQKQN------IPGGNR--- 183 Neisseria meningiti...
15676707 134 lPDPQTE---------SARQILAAEQHLLDSGv---PNIDILRLG-GLYCAERHPV-GRLVQKQN------IPGGNR--- 190 Neisseria meningiti...
15596756  54 ----RQQ----------GLERLRGNLLMHGVD---EADCLALRAEqILCGDFLDTS----WLAREtpRLMQVERVINc-- 110 Pseudomonas aerugin...
15596757   1 -----------------------------------mIPVDYCA-E-ALIGLALKPC-LGHSLYHI--SA--GHRAAC--- 35  Pseudomonas aerugin...
15602679 128 sPQPQSE---------IAKALVEVEEWLFQLKn---IDCDIIRFG-GLIGDDRHPV-YSLAGKD-------VKAGNS--- 183 Pasteurella multocida
13541188 115 --LEYFR----------TKRLVEDNTRVLKNgl--vVRLSIVFGD-GDHFTDRFVK-LAEQVSHL--P----EEGNL--- 169 Thermoplasma volcanium
16082244 121 --LEFFR----------TKRLVEDNTRVLKNgl--vVRLSFLFGE-GDHFTDRFRK-LSERVGHL--S----PEGNL--- 175 Thermoplasma acidop...
15641701 125 -DASLALAldnsafdAKARILLKAEQYVITSG----MDYTILRCS-GLMGPKRHPS----RFVSK---MAQVSRLAP--- 188 Vibrio cholerae
16121830 214 sIFWVFR----------MALMLRKFMCSLDDHid-vIPVDYCA-D-ALLYILEYPN-LPDDIYHI--SA--GEKGSV--- 272 Yersinia pestis
15793975 127 tPDPQTE---------SARQILAAEQHLLDSGi---SNIDILRLG-GLYCAERHPV-SRLVQKQN------IPGGNR--- 183 Neisseria meningiti...
15676707 134 lPDPQTE---------SARQILAAEQHLLDSGv---PNIDILRLG-GLYCAERHPV-GRLVQKQN------IPGGNR--- 190 Neisseria meningiti...
15596756  54 ----RQQ----------GLERLRGNLLMHGVD---EADCLALRAEqILCGDFLDTS----WLAREtpRLMQVERVINc-- 110 Pseudomonas aerugin...
15596757   1 -----------------------------------mIPVDYCA-E-ALIGLALKPC-LGHSLYHI--SA--GHRAAC--- 35  Pseudomonas aerugin...
15602679 128 sPQPQSE---------IAKALVEVEEWLFQLKn---IDCDIIRFG-GLIGDDRHPV-YSLAGKD-------VKAGNS--- 183 Pasteurella multocida
13541188 115 --LEYFR----------TKRLVEDNTRVLKNgl--vVRLSIVFGD-GDHFTDRFVK-LAEQVSHL--P----EEGNL--- 169 Thermoplasma volcanium
16082244 121 --LEFFR----------TKRLVEDNTRVLKNgl--vVRLSFLFGE-GDHFTDRFRK-LSERVGHL--S----PEGNL--- 175 Thermoplasma acidop...
15641701 125 -DASLALAldnsafdAKARILLKAEQYVITSG----MDYTILRCS-GLMGPKRHPS----RFVSK---MAQVSRLAP--- 188 Vibrio cholerae
16121830 214 sIFWVFR----------MALMLRKFMCSLDDHid-vIPVDYCA-D-ALLYILEYPN-LPDDIYHI--SA--GEKGSV--- 272 Yersinia pestis
1BSV_A   197 pDVVVWGSGTPMREFLH-VDDMAAASIHVMELAHEVwlentqpmlsHINVGTG------VDCTIRELAQTIAKVVGYKGR 269 Escherichia coli
15793975 184 -PINI----------VH-RNIAVESLFQTAFNPGGRr---------LKNIIEPr------HPTRREFYTEEAAKLGLPAP 236 Neisseria meningiti...
15676707 191 -PINI----------VH-RNIAVESLFQTAFNPGGRr---------LKNIIEPr------HPTRREFYTEEAAKLGLPAP 243 Neisseria meningiti...
15596756 111 -AAVASFSKNPTIWPVN-VDG-TFAFADVLSRSKRlk--------rFLHVGTAmccgpqRESPISESWEFPAAEQQLVDY 179 Pseudomonas aerugin...
15596757  36 -TFGE-------------IDEAFARANGAAPVGERYr---------KVEVDDLke---lAKSFESRIGPANPRLVLRALR 89  Pseudomonas aerugin...
15602679 184 -PVNL----------VH-FDDCARAIQLLLETPSHQr---------LYHVVAPk------HPTKAEYYSAMAEKLGVATP 236 Pasteurella multocida
13541188 170 -APVY-------------VGDVVTVVNSIIKREGVY----------DICSNDNlp---lIRIIN-YIRKNIGKKEIGSVK 221 Thermoplasma volcanium
16082244 176 -APVY-------------VDDVVKVVNSILKREGVY----------DICSNDNlp---lIKIVN-YIRKMNGKKEIGETK 227 Thermoplasma acidop...
15641701 189 -------------ANMLhLYDAIGIAHFSLEQLPy----------sIINATTPn------TVSKAEFYQAALDAVASDLP 239 Vibrio cholerae
16121830 273 -SFSE-------------IDQAMSVAAKQKPVGVNYs---------QVEYTALvq---mRNQLKGIFGPCNERLMLKAMR 326 Yersinia pestis
15793975 184 -PINI----------VH-RNIAVESLFQTAFNPGGRr---------LKNIIEPr------HPTRREFYTEEAAKLGLPAP 236 Neisseria meningiti...
15676707 191 -PINI----------VH-RNIAVESLFQTAFNPGGRr---------LKNIIEPr------HPTRREFYTEEAAKLGLPAP 243 Neisseria meningiti...
15596756 111 -AAVASFSKNPTIWPVN-VDG-TFAFADVLSRSKRlk--------rFLHVGTAmccgpqRESPISESWEFPAAEQQLVDY 179 Pseudomonas aerugin...
15596757  36 -TFGE-------------IDEAFARANGAAPVGERYr---------KVEVDDLke---lAKSFESRIGPANPRLVLRALR 89  Pseudomonas aerugin...
15602679 184 -PVNL----------VH-FDDCARAIQLLLETPSHQr---------LYHVVAPk------HPTKAEYYSAMAEKLGVATP 236 Pasteurella multocida
13541188 170 -APVY-------------VGDVVTVVNSIIKREGVY----------DICSNDNlp---lIRIIN-YIRKNIGKKEIGSVK 221 Thermoplasma volcanium
16082244 176 -APVY-------------VDDVVKVVNSILKREGVY----------DICSNDNlp---lIKIVN-YIRKMNGKKEIGETK 227 Thermoplasma acidop...
15641701 189 -------------ANMLhLYDAIGIAHFSLEQLPy----------sIINATTPn------TVSKAEFYQAALDAVASDLP 239 Vibrio cholerae
16121830 273 -SFSE-------------IDQAMSVAAKQKPVGVNYs---------QVEYTALvq---mRNQLKGIFGPCNERLMLKAMR 326 Yersinia pestis
1BSV_A   270 ----VVFDA----SKPDGTPRKLLDVTRLH-QLGWYHE-ISLEAGLASTYQWFLENQDR 318 Escherichia coli
15793975 237 d---FAPDDsvgkIIRTVCDN-------GLsL--------------------------- 258 Neisseria meningitidis Z2491
15676707 244 d---FAPDDsvgkIIRTVCDN-------GLsL--------------------------- 265 Neisseria meningitidis MC58
15596756 180 t---ASKAEie-rRMREELPGLPLVVARPSiVVGHRTLgCQASGSIFWSSAWASPWKAS 234 Pseudomonas aeruginosa PA01
15596757  90 lysgFADLNylfdNSRLLEEGISAPP-RFTdYLDVCVQ-S-SSAVSIPAQMQWDFK--- 142 Pseudomonas aeruginosa PA01
15602679 237 h---FICSEqd-pVRIIVSDK-------ICqEIDFVYQ-YPDPYLMLPNEEKSGGLSDG 283 Pasteurella multocida
13541188 222 lekgLSMLTetglFSRYEAELMFQDYYRETsILDRYVK-NPTSYLDFLRSILVEHTT-- 277 Thermoplasma volcanium
16082244 228 lekaISAVVetglFAEYEAHLLFQDYYRETnILDRYVK-DPLSYLDFLRGISVTHTT-- 283 Thermoplasma acidophilum
15641701 240 -------------LPPLCDKEEKRIVCDKLlAAGYRFHfSHTLEAVHGYE--------- 276 Vibrio cholerae
16121830 327 lygsFAMLNvrfsNERLLSLGMPRTP-RFTdYIARCVE-S-SHGMTIQQQMAVDFK--- 379 Yersinia pestis
15793975 237 d---FAPDDsvgkIIRTVCDN-------GLsL--------------------------- 258 Neisseria meningitidis Z2491
15676707 244 d---FAPDDsvgkIIRTVCDN-------GLsL--------------------------- 265 Neisseria meningitidis MC58
15596756 180 t---ASKAEie-rRMREELPGLPLVVARPSiVVGHRTLgCQASGSIFWSSAWASPWKAS 234 Pseudomonas aeruginosa PA01
15596757  90 lysgFADLNylfdNSRLLEEGISAPP-RFTdYLDVCVQ-S-SSAVSIPAQMQWDFK--- 142 Pseudomonas aeruginosa PA01
15602679 237 h---FICSEqd-pVRIIVSDK-------ICqEIDFVYQ-YPDPYLMLPNEEKSGGLSDG 283 Pasteurella multocida
13541188 222 lekgLSMLTetglFSRYEAELMFQDYYRETsILDRYVK-NPTSYLDFLRSILVEHTT-- 277 Thermoplasma volcanium
16082244 228 lekaISAVVetglFAEYEAHLLFQDYYRETnILDRYVK-DPLSYLDFLRGISVTHTT-- 283 Thermoplasma acidophilum
15641701 240 -------------LPPLCDKEEKRIVCDKLlAAGYRFHfSHTLEAVHGYE--------- 276 Vibrio cholerae
16121830 327 lygsFAMLNvrfsNERLLSLGMPRTP-RFTdYIARCVE-S-SHGMTIQQQMAVDFK--- 379 Yersinia pestis
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