Conserved Protein Domain Family
SbcD

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COG0420: SbcD 
DNA repair exonuclease SbcCD nuclease subunit [Replication, recombination and repair]
Statistics
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PSSM-Id: 223497
View PSSM: COG0420
Aligned: 47 rows
Threshold Bit Score: 132.647
Threshold Setting Gi: 16082827
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1709096    9 IRILITTDNHVG-YNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKPSKKSLYQVLKTLRLCCMgdkpcel 87  baker's yeast
11498636   1 MKFAHIADVHLGyEQYNQPWRAEDFAKAFKVIAEKAVESNADFVVIAGDLFHRSLPSPRTIKEAVETLWMFRK------- 73  Archaeoglobus fulgidus
20090029   5 IRILHTADTHLGyRQYHSEVRRQDFFKAFETVIQDAVDMQVDAVVHAGDLFDSRNPTLEDLLETMNILSRLKA------- 77  Methanosarcina acet...
20094128   1 MRMAHVADVHLGhALMNLRSREEAVMETFERLMEEVRECSVDVLVIAGDLFEHARPKTEALYLAVEKLSELKE------- 73  Methanopyrus kandle...
14521424  11 IKFAHLADVHLGyEQFNRSQRAEEFAKAFEDAIKICVDEKVDFIVIAGDLFNSSRPSPGTIKTAVKILQIPRD------- 83  Pyrococcus abyssi
14590783   1 MKFAHLADVHLGyEQFNKPQRAEEFANTFKKALEMCVKESVDFIIIAGDLFNSSRPSPGTIKTAIKLLQIPKE------- 73  Pyrococcus horikoshii
15899023   2 VQILHISDTHLGkRQYSLVEREKDIYDIFSQLVDIAIKEHVDVIIHSGDLFDVSSPTTNALVMAIKILKRLKD------- 74  Sulfolobus solfatar...
13541059   1 -----MSDTHIGaKSLTIEEREQDYYDTFQEAVEIAIDEKVDFIIHSGDLFDTWIPGNRSMKVFRDAMMKLND------- 68  Thermoplasma volcanium
16081318   1 ---MHFSDTHIGyRSLTLDEREQDFYDAFHEAIDIALENSVDFVIHTGDLFDTWVPGNRAIREFRNAVMKLNA------- 70  Thermoplasma acidop...
15789740   2 ARVIHTGDTHLGyQQYHAPQRRQDFLDAFDAVITDAIDEGVDAVVHAGDLYHDRQPGLRDILDTIALLRPLQD------- 74  Halobacterium sp. N...
1709096   88 ellsdpsqvfhydeftnvnyedpnfnISIPVFGISGNHDDASGDSLLCPMDilhatgLINHFGKVIESDKikvvplLFQK 167 baker's yeast
11498636  74 --------------------------ENIPVFAVEGNHDKTSRDISAYHL-------LESLGLLNVLGLRrn---pVRGE 117 Archaeoglobus fulgidus
20090029  78 --------------------------VDIPFFGIVGNHESKQNTQWLDLFEem--glAERLGKTPKLVGNt----tIYGI 125 Methanosarcina acet...
20094128  74 --------------------------DGVEIVATAGNHEIRRRKGAVSPIS------VLERMGLVRHLY--------YSE 113 Methanopyrus kandle...
14521424  84 --------------------------NNIPVFAIEGNHDRTQRGPSILHL-------LEDLGLLYVLGVRde---kVENE 127 Pyrococcus abyssi
14590783  74 --------------------------NNIPVFAIEGNHDRTQRGPSVLHL-------LEDLGLLYVIGLRqe---rVENE 117 Pyrococcus horikoshii
15899023  75 --------------------------VNIPFLSIPGDHDTPKRKGYLIPHN------ILSELDLIKILN----------- 111 Sulfolobus solfatar...
13541059  69 --------------------------RQIPVFYVFGDHDRPRRNSESAAG-------IFDFLGLHILGRD-------EFA 108 Thermoplasma volcanium
16081318  71 --------------------------RNIPIFVIFGDHDRPRRNGEPAAG-------IFDFMGVHVLGWD-------AYE 110 Thermoplasma acidop...
15789740  75 --------------------------ADIPFLAVVGNHEGTRDAQWLDLF---------ETLGLAERLD---------D- 109 Halobacterium sp. N...
1709096  168 GSTKlalygLAAvRDERLFRTFKDGGVTFEVPTMREGEWFNLMCvhqnhtgHTNTAFLPEQFlpdFLDMVIWGHEHECip 247 baker's yeast
11498636 118 NVES-----LRI-QNVYLVKGVVDDVE-ILGDRHRSKWQLEKVL---------P---LLKPQ---SDKSVLVLHQAVK-- 173 Archaeoglobus fulgidus
20090029 126 DSVPks-kiPLYdYSGFELPDSLPENCKKLLVMHQIVQPFPYADw-----dCAEVLENLPFKv--DAILLGDYHKYEKi- 196 Methanosarcina acet...
20094128 114 RRPE---------RHRYTATFDGVRVT-FHGLQYLPKNSFVERA--------KVIRAKYRPDp-eADVNVAIFHQ----- 169 Methanopyrus kandle...
14521424 128 YLTS-----EKT-KAGWLVKGMYKDVE-IHGMKYMSAAWFEGNI--------ELFKSMFRP----EGDAILVLHQGVR-- 186 Pyrococcus abyssi
14590783 118 YLTS-----ERV-GNYWLVKGVYDNLE-IHGMKYMSSAWFEANL--------NFFKGIFRP----DEDAILVLHQGIR-- 176 Pyrococcus horikoshii
15899023 112 -----------Y-EKPYIIKG----IE-VYGIPHIPTVSKSILVs---------ALSALRPK---SSRSILLLHQG---- 158 Sulfolobus solfatar...
13541059 109 GIER-----EFS-GMKVFIGG-------ISNMKGYLRNQLKEEY--------KKAESASTG----YKNSILISHQ----- 158 Thermoplasma volcanium
16081318 111 YAVR-----KFD-GEDVLIGG-------ISNMKGYMKTRLKDEY--------KRSENIEEG----YRNRILMSHQ----- 160 Thermoplasma acidop...
15789740 110 --------------SPRVVAD-----TAFYGLDYVPQSKRDDHD---------YTVADHDA-----DHAALVSHG----- 151 Halobacterium sp. N...
1709096  248 nlvhnpiknfdvlqpgssvatslcEAEAQPKYVFILDIKYgeapkMTPIPLETirtfkmksISLQDVPHLrpHDKDATSK 327 baker's yeast
11498636 174 ------------------------EVVDIDLD-MAYELT------INDLPEA----------SYYAFGHI--HLPKIYEF 210 Archaeoglobus fulgidus
20090029 197 -----------------------kVGEEETWATYSGSTERns--aSENEPRSYn------iITLSGEGLE--ISRRTIPT 243 Methanosarcina acet...
20094128 170 -------------------------ALPGTIPDESEIVEP------AYFPEG---------HDYYAMGHV--HVPSREEK 207 Methanopyrus kandle...
14521424 187 ------------------------EITENNYPNYSSELS------LSDLPKG---------YLYYALGHI--HKRFELTY 225 Pyrococcus abyssi
14590783 177 ------------------------DITEKVFPSYSAELK------LSDLPRG---------YLYYALGHV--HKRFETNY 215 Pyrococcus horikoshii
15899023 159 -------------------------VKQILPYDGSWQME------LGSLPKG---------FGYYALGHI--HTRWRLTQ 196 Sulfolobus solfatar...
13541059 159 ------------------------ALDPIFIP-EQCEAK------VNDLPMN---------YSYIAMGHL--HDFVEREI 196 Thermoplasma volcanium
16081318 161 ------------------------AIDPFFVP-DQCEAK------MDDLPMN---------FSYIAMGHL--HDFMERRI 198 Thermoplasma acidop...
15789740 152 ------------------------LFTPFPYANWDLDAV------LADATVE---------FDAVLLGDN--HTPDTAQL 190 Halobacterium sp. N...
1709096  328 YLiEQVeeMIRDANEETKqkLADDGEGDMVAelpkplirlRVDYSAPSntQspidyqvenprrfsnrfvgrvangnnvvq 407 baker's yeast
11498636 211 DG-KAI--AYPGSVERYD--LREASKIVRYRdel----vlKDGIRKGFilV----------------------------- 252 Archaeoglobus fulgidus
20090029 244 RNfLFItaKIDGEEKPYEqiFSAINEHLEEIpes----vvFLDISGNSdsV----------------------------- 290 Methanosarcina acet...
20094128 208 IHgSPA--PYPGSPEPLT--FLEVKDERGAHkrr---gffLVEFDRGG--L----------------------------- 249 Methanopyrus kandle...
14521424 226 DD-APV--VYPGSLERWD--FGDYSLKLTWNgfq---fkeEVGVDKGFyiV----------------------------- 268 Pyrococcus abyssi
14590783 216 GD-SPV--VYPGSLERWD--FGDYAKRLVWNgvt---freEVGSDKGFyiV----------------------------- 258 Pyrococcus horikoshii
15899023 197 DDgSVI--AIAGSPDIMR--EEEIEGYEKFGkg-----ayLIDFSKDLp-I----------------------------- 237 Sulfolobus solfatar...
13541059 197 G--PLL--SYPGSTELKS--DREINGLLKMGkg-----inVIDLDNGVasL----------------------------- 236 Thermoplasma volcanium
16081318 199 G--PLI--SYAGSTEIKS--ENEINGYLKQGkg-----vnIVDISNGEvdL----------------------------- 238 Thermoplasma acidop...
15789740 191 GDtWVT---YCGSTERAS---ASERDPRGYN---------IVSFSSDAttD----------------------------- 226 Halobacterium sp. N...
1709096  408 fykkrspvtrskksgingtsisdRDVEKLFSESGGELEVQTLVNDLLNKMQLSLLPEVGLneavkkfvdkDEKTALKEFI 487 baker's yeast
11498636 253 -----------------------KNFRPEFVEIETRELYDVEIEDESVEGLEKKFLEVLGr--------aDKEGIMVAKL 301 Archaeoglobus fulgidus
20090029 291 -----------------------LSFSEIEEYLLSKGALVSKVKDARIKETLPEEVAKVAf--------sDPDHAVAEEI 339 Methanosarcina acet...
20094128 250 -----------------------VEYEFVEVEWSRELSVVEVSGERWEEELRRRVRRGQIvkvvakdtgaSPEEVEKVAI 306 Methanopyrus kandle...
14521424 269 -----------------------EDFKPRFIRINARDFIDVHIKGHSENEIKKAVKLAVPk--------iPRNSYVRFNI 317 Pyrococcus abyssi
14590783 259 -----------------------EDFTPRFVNIKVRDFIDVVIKGDSEREIKKAVKASLPh--------iPRNSYVRFNI 307 Pyrococcus horikoshii
15899023 238 -----------------------LSTINITVRPQKVVTINTKNIKKDILTIRDDLIEHNKs--------eNNKPILHIIV 286 Sulfolobus solfatar...
13541059 237 -----------------------HRVKLKKVRYQFKVESDPENYLEEIKSILDKYANAIGe--------kKPIVNLIING 285 Thermoplasma volcanium
16081318 239 -----------------------QRIRLKSVRPQIRVESDADNYVHEISEKLSSLRVKDNe--------kKPLVGLEIHG 287 Thermoplasma acidop...
15789740 227 -----------------------VAISRKSLNTREFVFVDADLGPTDGTAFIQERLRERa----------LDDAVVVVTI 273 Halobacterium sp. N...
1709096  488 SHEIsnevgiLSTNEEFLRTddaeeMKALIKQVKRANSVRPTPPKENDETnfaFNGNGLDSFRSSNREVRTgspditqsh 567 baker's yeast
11498636 302 KSSD------AVDVRRLSEVa---aKRVRYAEIRFERILEEIEEVEIKQEs--EFFTEFELKLLELLRGEMdedevyslv 370 Archaeoglobus fulgidus
20090029 340 RRMSlnd-ggLIVDEIIRSPdvvrsRVDEETENRLLRLIETIDFEDPDFRi-eIPASPISSTDSIDPVSPInhpvssads 417 Methanosarcina acet...
20094128 307 EAGAdrcvveLRERRREVEEgdeteGPLDLEGIIREGVKRARAATLTRVDvpdDVVVEVALEILRGVREDNppd---lgd 383 Methanopyrus kandle...
14521424 318 RWKR------PVDVDWIKSI-----VNAEYVRV-NPIIIKEERGPDGKDLdvkKFFTELEWKIIELASEKE--------- 376 Pyrococcus abyssi
14590783 308 KWRK------PFDVEWIKEI-----VNAEYLRI-HTAIIKDEKSMNGESVdikSFFTEQEWKVIDLASSDE--------- 366 Pyrococcus horikoshii
15899023 287 EGER------MRKDLLYKELlp-lnDVALYYRIYKDETTQTVDNLSYTLPrdkGLDKIIIEYLTKYEKFSE--------- 350 Sulfolobus solfatar...
13541059 286 QISM------EEVYEDLKKI-----NGAIFNR---PQILKIVDMPNv-----pSGSSELREYFQAFLKDQK--------- 337 Thermoplasma volcanium
16081318 288 DISM------ETVMQDISKF-----DNAIFSR---PKIRKDPKIPNi-----hTETADLREYFRAYLGDER--------- 339 Thermoplasma acidop...
15789740 274 TGDG------DTVTPAEIERfgddrGALLTRVNDRREFDTGDDAPDVDVSf-aDPDDAVEQRVRDLGLDEPar------d 340 Halobacterium sp. N...
1709096  568 VDNESRITHISQAESSkptskpkRVRTATKKKIPAFSDST 607 baker's yeast
11498636 371 VEHYLSGGALKQEEGAeer-vveEETEKKVEEQFKGDEEA 409 Archaeoglobus fulgidus
20090029 418 VSAVSPESSADHVSPDiie-nneKPIPAVEAEKIETLDPA 456 Methanosarcina acetivorans C2A
20094128 384 VEGIVAGEPPSEGSEEsseepeeSDGEEVGLEVEEVKVES 423 Methanopyrus kandleri AV19
14521424 377 YEYYLNQIIDLLASEEgkv-eakIDAKREEKKFVRPKNPG 415 Pyrococcus abyssi
14590783 367 FESYIEKIVDILSGYEkke--erEKKESKIRKFERPKNPG 404 Pyrococcus horikoshii
15899023 351 DEANLILQMIKNVESD-------EIVNEILKKLTGVNL-- 381 Sulfolobus solfataricus
13541059 338 LTDLAMKVFQHTADGD-------KEAIIREAAGEAIDN-- 368 Thermoplasma volcanium
16081318 340 LADLAMKIMAHSRSKD-------IDGIMKEIEVLYGDNRQ 372 Thermoplasma acidophilum
15789740 341 VDRIVRDDTLADAAVRer---viQRAEAVLDDDADAADDD 377 Halobacterium sp. NRC-1
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