1HZP,1HNJ


Conserved Protein Domain Family
FabH

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COG0332: FabH 
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3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]
linked to 3D-structure
Statistics
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PSSM-Id: 223409
View PSSM: COG0332
Aligned: 63 rows
Threshold Bit Score: 151.224
Threshold Setting Gi: 15596194
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HZP_A    10 ARSVGLLSVGAYRPERVVTNDEIC-------QHIDSSDEWIYTRTGIKTRRFAAD-------------DESAASMATEAC 69  Mycobacterium tuber...
15614407  13 TVSPRIIGFGECLPGEPVTNEQME-------QLLSIRKEWLETMIGNRSRHFAVNfss-------rtiDYGLADLCTEAA 78  Bacillus halodurans
15895281   8 NNYVKLLGIGACLPGNPIKFEDINnyigqipNAPKKIKTWISRVQPIMKEMLGIDycyyafngktrkfDEDNLSLSVKAS 87  Clostridium acetobu...
16125118  24 NDQAYITGVGAFLPGEPVPSAAMEdfigrigGRGSLMGRRALRWNGVETRHYALSpgg--------rpNHSNAGMCALAV 95  Caulobacter crescen...
15596194   1 ---------------MLIQAVGVN---------LPPSYVCLEGPLGGERPRAQG--------------DEMLMQRLLPAV 42  Pseudomonas aerugin...
15596195   1 MHKVKLAAITCELPARSYENDDPVf-----aAVPDLSESWWQFWGVNRRGYFDPRn------------GENEFSLVVRAA 63  Pseudomonas aerugin...
15598482  13 DQHAEAIAKGELEALAESSSAFIEkas-gikSRFVMNKEGILDPQRMVPYLPERSnd----------eWSILCEMAVAAA 81  Pseudomonas aerugin...
17548415  36 EANADAIAAGELAAVAESSVEFIEkas-girQRYVIDKAGVLDPARMRPRLAPRGdd----------tLSLQAEIGVAAA 104 Ralstonia solanacearum
15838564   3 FNNVSIAGLAHIDAPCTLTSQEINarlqpmlERIGIKSDVFADIVGINARRLWNT-------------NVQTSDVATMAA 69  Xylella fastidiosa ...
13471587   1 -----------------------------mkSRHVIEREGILDPTRMTPRIPARPdd----------aLSLEAEFGIASA 41  Mesorhizobium loti
1HZP_A    70 RRALSNAGLSAADIDGVIVTTNT--HFl-----------qTPPAAPMVAASLGAKG-ILGFDLSAGCAGFGYALGAAADM 135 Mycobacterium tuber...
15614407  79 VEAIDDAGINAEELDLIVLSTATpdHL-------------MPATVNIVADRLGLER-VKTYQIQAGCSGALQALDVAR-H 143 Bacillus halodurans
15895281  88 KLALQDAKIKPQDIDLLIYAGNYsyQM--------------PPISTRIQEELGIDI-CSEYHIHSNCSSIYKAIKLADTF 152 Clostridium acetobu...
16125118  96 RRALDDAGLGPEDLGFLAAATTQgdFL-------------VPGHAAMVHGELGCGP-IEIASFQSVCASSLMAAKSAYLS 161 Caulobacter crescen...
15596194  43 REALDEAAVKPEEIDLIVGLALSpdHLienr------dimAPKIGHPLQKVLGANR-AHVFDLTDSS--LARALYVVDTL 113 Pseudomonas aerugin...
15596195  64 ERLLRSSDTAPDSVDMLICSASSpiMTdagdvlpdlrgrlYPRMANVLSKQLGLSR-ALPLDSQMECASFLLNLRLAASM 142 Pseudomonas aerugin...
15598482  82 REALQRAGRSAADIDGVIVACSNlqRA-------------YPAIAVEVQAALGIQG--YGYDMNVACSSATFGIQAATTA 146 Pseudomonas aerugin...
17548415 105 REALAAAGREAADIDMLICSAANmqRP-------------YPAMGIEIQNALGAGG--YAFDMNVACSSATFGLEQAVNA 169 Ralstonia solanacearum
15838564  70 RKALQDAGVAVDRIGLVVNTSVSrdYL-------------EPSTASIVSGNLGVGEqCIAFDVANACLAFLNGMDIAGQM 136 Xylella fastidiosa ...
13471587  42 RKALDHAGVEPSQIDLIICSASHhqRP-------------YPAIAIEMQEALGTTG--AGFDMGLGCSSAAAALHMAVNL 106 Mesorhizobium loti
1HZP_A   136 IRGGGAAT-MLVVGTEKL----------SPTIDMYDR---------GNCFIFADGAAAVVVGET-------PFQGIGPTV 188 Mycobacterium tuber...
15614407 144 MLVGSHRY-ALVIGGDVC----------NKYMDLSRDfsklrsselINYALFGDGAGAVVLTNEnq---dgLQISYIENR 209 Bacillus halodurans
15895281 153 LKSGEYKN-ALVVSSMVSsahfipeyynQQKVTKEDV---------FLRWYLCDGAGAVVLSSKd-----tVDNGFYLKN 217 Clostridium acetobu...
16125118 162 VRTGEHRVaAACAGEFSSrwfqpsfyegSSLLDDKQRlkp---qadYLRFTLSDGAGAVLVEPAprp--qgLSLRIRFID 236 Caulobacter crescen...
15596194 114 ASDQGYRN-VLVVRGESS-----------QGLEVDSE----------SGFALADGALALLCRPTg-------KAAFRRGA 164 Pseudomonas aerugin...
15596195 143 IRQGKAEK-VLVVCSEYI----------SNLLDFTSR----------TSTLFADGCAVALLTRGdd-----dSCDLLASA 196 Pseudomonas aerugin...
15598482 147 IQTGQARA-ILMVNPEIC----------TGHLNFRDR---------DSHFIFGDACTAVIVERAdla-vskHQFDIVSTR 205 Pseudomonas aerugin...
17548415 170 VRTGSARM-ALMVNPEIT----------SGHLAWQDR---------DCHFIFGDVCTAVVVERAdda-rarDQWHVLGTR 228 Ralstonia solanacearum
15838564 137 LERGDIDY-ALVVNAETA----------NRVYEKTLErms---apgVTEQEFREEMAALTLGCGa------vAMVLARTA 196 Xylella fastidiosa ...
13471587 107 VRSGAHKR-ILVTTPEII----------TGHLNFRDR---------QTHFIFGDASVSMVVEGLaqgdkrpGRFEVLDTR 166 Mesorhizobium loti
1HZP_A   189 AGSDGEQA-DAIRQDIDWITf----------aQNPSGprPFVRL-EGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFV 256 Mycobacterium tuber...
15614407 210 FEGKGRAPgQIMNWFGTVPEnvq------elsKRELRkqFQSAKeDYKAIEQHVPIMTEQAIEELLGQMKWTKEEVSYYL 283 Bacillus halodurans
15895281 218 TYVESAGG-KKESVMGNNFPsyfsnpltayenGEHHIrqVTLDKmRKYVVDENGKTIFYNALKRMLDKQKIDLSTLKYFM 296 Clostridium acetobu...
16125118 237 MVSLAGQFdPCMWAGAGLEShaealdgwshlgPQAAHraGGLALlQDFDLLKRVIRAWVGVYLKKVDEGRIVPDEIDHLL 316 Caulobacter crescen...
15596194 165 LGGDPAQEwLPLSIPLN-----------------------TDIRqVGDVKGHLNLPAQPGLPEAVRAGFTRLAGDFPQLN 221 Pseudomonas aerugin...
15596195 197 EHSDATFY-EVATGRWRLPEnp--------tgEAKPRlyFSLFSdGQNKMASFVPTNVPIAMRRALEKAGLGSDDIDYFV 267 Pseudomonas aerugin...
15598482 206 LLTQFSNNiRNNFGFLNRADes------------gIGkrDKLFVqEGRKVFKDVCPMVAELIGEHLAANEIQVAEVKRFW 273 Pseudomonas aerugin...
17548415 229 MATRFSNSiRNNAGFLSRSEdr------------hPDdrDQLFRqEGRKVFKEVCPMAAEHIAGHLQALGHAPADVRRFW 296 Ralstonia solanacearum
15838564 197 LVPDAPQYkGGVTRSATEWNklc---------cgnLD----RMVtDTRLMLIEGIKLAKKTFVVAKQVLGWAVEELDQFV 263 Xylella fastidiosa ...
13471587 167 LWTQMSNNiRTNLGYHTRTAqd---------dpYMINleGNLIKqVGNKVFKEVTVAGQKFIVEFLAEHGLTPQAIRRFW 237 Mesorhizobium loti
1HZP_A   257 PHQANSRINELLVKNLQLr----PDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPG--DLAL-LIGYGAGLSYAAQV 329 Mycobacterium tuber...
15614407 284 PPQLGWNMTKKIIDLLGL-----PLDSTINCVQETGNNGNALPYLQLKRLNGILKPNDKv-VGVA-IESSKWMKTGITLE 356 Bacillus halodurans
15895281 297 VNMPSKFVREYITNECVGlg--iSPDKFYSVSQKIGYAGPPAAIISLDRLLKNNDFKNN--DLIFsFVLEVSKFMQGGFT 372 Clostridium acetobu...
16125118 317 CHYSARSLREEIVSLLEKtngmiPEEKWFSNLATVGNVGSASIWVMLEAFLRSDRLKPGqtVLCV-VPESGRSMVGFMLL 395 Caulobacter crescen...
15596194 222 WVREEWFGQGRPDGRCLG--------PFELASQLRAAQRDRLDELLLISFDPFGMVVEG----VT-LELAGEAHA----- 283 Pseudomonas aerugin...
15596195 268 FHQPAPFLVKAWAEGIGA-----RPEQYQLTMGDTGVMISVSIPYTLMTGLREGKIRPG--DRIV-MAGAATGWGFAAQV 339 Pseudomonas aerugin...
15598482 274 LHQANLNMNLLITRKLLGrd--aEAHEAPVILDSYANTSSAGSVIALHKH--QDDLPSG--AIGV-LSSFGAGYSIGSVI 346 Pseudomonas aerugin...
17548415 297 LHQANLGMNQLIGKRLLGrd--aTADDAPVILDEFANTASAGSIIAFHRH--RGDLRPG--DLGV-ICSFGAGYSIGSVA 369 Ralstonia solanacearum
15838564 264 IHQVSRPHTEAFIKSFGI-----DPAKVMTIFREYGNIGPASVPIVLSKLKELGRLKKG--DRIA-LLGIGSGLNCSMAE 335 Xylella fastidiosa ...
13471587 238 LHQANARMNAMILKLSFGhd--vDHDRAPMVLERLGNTAGAGAIVALSEN--HADMKPG--DFGL-ICAFGAGYSIGGAL 310 Mesorhizobium loti
1HZP_A   330 VRMP 333 Mycobacterium tuberculosis
15614407 357 YKKG 360 Bacillus halodurans
15895281 373 IQYI 376 Clostridium acetobutylicum
16125118 396 EAVG 399 Caulobacter crescentus CB15
15596194     ---- Pseudomonas aeruginosa PA01
15596195 340 WQLG 343 Pseudomonas aeruginosa PA01
15598482 347 LRKH 350 Pseudomonas aeruginosa PA01
17548415 370 VRKR 373 Ralstonia solanacearum
15838564 336 VVW- 338 Xylella fastidiosa 9a5c
13471587 311 IRML 314 Mesorhizobium loti
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