1E5M,1FJ8,1DD8,1EK4,1F91


Conserved Protein Domain Family
FabB

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COG0304: FabB 
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3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
linked to 3D-structure
Statistics
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PSSM-Id: 223381
View PSSM: COG0304
Aligned: 105 rows
Threshold Bit Score: 152.8
Threshold Setting Gi: 15595296
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1E5M_A      5 EKKRVVVTGLGAITPIGNTLQDYWQGLM-----------------------------------------------EGRN- 36   Synechocystis sp....
15888910    3 SDNDVVITGVGIVTCHGVGSQAHVALLS-----------------------------------------------GAAV- 34   Agrobacterium tum...
17987395    2 QNNKVVITGIGLISSLGEGVEAHWNAFS-----------------------------------------------KAG-- 32   Brucella melitensis
15830544      -------------------------------------------------------------------------------- Escherichia coli ...
15595296    1 ---------------------------------------------------------------------------MSQAl 5    Pseudomonas aerug...
15600367   36 QARQETLAGLAVMMKLVKAEGGRYLAEDgtplspedierryaerifastlvrriepqyldpdavhwhkvlelspaEGQAl 115  Pseudomonas aerug...
15965693    4 SANDVVITGVGIVTSQGVGAEPHVALLG-----------------------------------------------AAKP- 35   Sinorhizobium mel...
20981695 1106 iepelfngynpekkemiqeviveedlepfeasketaeqfkhqhgdkvdifeipetgeysvkllkgatlyipkalrfdrLv 1185 baker's yeast
15801038    1 MDNAAIISGYSVWMPYAEDCSQLIDNLK-----------------------------------------------QGKRv 33   Escherichia coli ...
13471256    3 SPCDVVITGIGLVSSLGEGPDAHWQKLA-----------------------------------------------QPG-- 33   Mesorhizobium loti
1E5M_A     37 GIGPITRFDASDQa----------CRFGGEVKDfd-----------------aTQF-LDRKEAk--RMDRFCHFAVCASQ 86   Synechocystis sp....
15888910   35 PEPVVETEKFKPYp----------VHPMPEIDWs--------------------AQiAKRGDQr--QMENWQRLGVFAAG 82   Agrobacterium tum...
17987395   33 TQPHLEKQAFAPYt----------VHPLGEVDWs--------------------LQiPKRGDQr--QMETWQRLGTYAAG 80   Brucella melitensis
15830544      -------------------------------------------------------------------------------- Escherichia coli ...
15595296    6 SIVASGMVSAVGLs----------APASCAAIR--------------------CALdNFQETR---FIDQGGEWLLAASV 52   Pseudomonas aerug...
15600367  116 TFKASPKQLPEPLpanwsiapaedGEVLVSIHErcefkvdsyraltvksagqlPTGfEPGELYnsrFHPRGLQMSVVAAT 195  Pseudomonas aerug...
15965693   36 PGVRIETERFAPYp----------VHPLPEIDWs--------------------QQiPKRGDQr--QMENWQRLGVFAAG 83   Sinorhizobium mel...
20981695 1186 AGQIPTGWNAKTYg-----------IS-DDIIS---------------------------------QVDPITLFVLVSVV 1220 baker's yeast
15801038   34 ARTPWFTSNEEAIk----------CGFKGNPSV------------------------ATLKQVddsALDLLSQLIDEALE 79   Escherichia coli ...
13471256   34 LQPVLEAARFAPYt----------VHPLPEIDWn--------------------LQiAKRGDQr--QMETWQRLGTYAAG 81   Mesorhizobium loti
1E5M_A     87 QAINDAKLVi---NELNAD--EIGVLIGTGIGGLKVLED---------QQTILLDKGPSR-CSPFMIPMMIANMASGLTA 151  Synechocystis sp....
15888910   83 LALDDAGLKe---NTEACAtmDMIVAAGGGERDINVDTLivdealkrnDREKLLNEKLTTeLRPTLFLAQLSNLMAGNIS 159  Agrobacterium tum...
17987395   81 LALQDAGMKg---DEALCAtmDMIVGAGGGERDITVDMQileegrtsnNRGVMLNEKLSTeLRPTLFLAQLSNLLAGNIS 157  Brucella melitensis
15830544    1 --MLDKHCL----AGRNVR--VYLTGIGPRIDGLDYKSFy--------nYNDVEDINLTQsITNLHASKMSQDTISSHLA 64   Escherichia coli ...
15595296   53 PLEQPWRGR----AKLLK---MAARAIDEALRGQP-------------DLDCTELPLLLC-VAEGDRPGRCAGLDESFLR 111  Pseudomonas aerug...
15600367  196 DAIRSTGIDwk-tIVDNVQpdEIAVFSGSIMSQLDDNGFg--------GLMQSRLKGHRVs-AKQLPLGFNSMPTDFINA 265  Pseudomonas aerug...
15965693   84 LALDDAGLKd---SLEACGsmDMIVAAGGGERDINVDSLivdealkrnDRERLLNEKLTTeLRPTLFLAQLSNLLAGNIS 160  Sinorhizobium mel...
20981695 1221 EAFIASGITdpyeMYKYVHvsEVGNCSGSGMGGVSALRG-----------MFKDRFKDEPvQNDILQESFINTMSAWVNM 1289 baker's yeast
15801038   80 QAMLDKHCL----AGRNVR--VYLTGIGPRIDGLDYKSFy--------nYNDVEDINLTQsITNLHASKMSQDTISSHLA 145  Escherichia coli ...
13471256   82 LALDDAGIKg---NDELCTtmDMVVAAGGGERDEAVDAAilaasesrnDRDVLLNEKLTTeLRPTLFLAQLSNLLAGNIS 158  Mesorhizobium loti
1E5M_A    152 INLGAKGPNNCTVTACAAGSNAIGDAFRLVQNGYAKAMICGGTEAAITPLSYAGFASARALSFR-----ND-----DPLH 221  Synechocystis sp....
15888910  160 IVHKVTGSSRTFMGEEAAGISAVETAFHRIRSGESSHALVGGAFSAERPDMILLFEAIGAHAQG------------GWQP 227  Agrobacterium tum...
17987395  158 IVHKVTGSSRTFMGEEGSGISAIETAAARIRTGQSTHALVGGSYNAEHFDMILGAELGGLLKHD------------GWAA 225  Brucella melitensis
15830544   65 RKYRLQYLPPNMNCTSNSSLTAVHLATQGIEQGGIDLAIVLNC-SKIKTQDIWFLETQSMLDSE---------------- 127  Escherichia coli ...
15595296  112 DLEGELGRRFHPSSALIARGR-VGGAVALLN---ARKLIQGGC-RQVLVAGVDSFVSGPTLAAY-------------EAR 173  Pseudomonas aerug...
15600367  266 YVLGSVGMTGSITGACATFLYNLQKGIDVITSGQARVVIVGNSEAPILPECIEGYSAMGALATEeglrlIEgrddvDFRR 345  Pseudomonas aerug...
15965693  161 IVHKVTGSSRTFMGEEAAGISAIETAFARIKAGQSSHTLVGGAFSAERLDIVLMIEAIQGHALG------------EWHP 228  Sinorhizobium mel...
20981695 1290 LLISSSGPIKTPVGACATSVESVDIGVETILSGKARICIVGGYDD-FQEEGSFEFGNMKATSNTl----EEfehgrTPAE 1364 baker's yeast
15801038  146 RKYRLQYLPPNMNCTSNSSLTAVHLATQGIEQGGIDLAIVLNC-SKIKTQDIWFLETQSMLDSE---------------- 208  Escherichia coli ...
13471256  159 IVHKVTGSSRTFMGEEGAGVSAVETAAARIRSGQSTHVLVGGAFQTEHSDMLLGYELAGYLHRG------------PWKP 226  Mesorhizobium loti
1E5M_A    222 ASRPFDKDRDGFVMGEGSGILILEELESALARGAKIYGEMVGYAMTCDAYHITAPVP----DGRGAT------------- 284  Synechocystis sp....
15888910  228 LWSRGDQDGGGMISGSLGAFLVLESRKHASERGARIYARIDAIEGDRGSRDDGKME------------------------ 283  Agrobacterium tum...
17987395  226 LWSRDGSAGGGMISGSGGVFLVLESVDHAQKRGARAYAEISGIESAQIRRSTADLE------------------------ 281  Brucella melitensis
15830544  128 QVQPFGENSKGVAFAEGFSALLLESAHHRRARQQSEGVRVQTTYTQISAGRSNDASW----LSTNVH------------- 190  Escherichia coli ...
15595296  174 ERLLTSQNSNGFIPGEGAAAVLVAAPLHEEAP--QLLCIGLGFGVEKATVESEDLPLr----ADGLS------------- 234  Pseudomonas aerug...
15600367  346 ASRPFGE-NCGFTLAESSQYVVLMDDELALRLGADIHGAVTDVFINADGFKKSISAP-----GPGNYlt----------- 408  Pseudomonas aerug...
15965693  229 IWSRKPEDGGGMILGSVGAFLVLESREYAESRGARIYAAIDAIGGDRGGREDGRLE------------------------ 284  Sinorhizobium mel...
20981695 1365 MSRPATTTRNGFMEAQGAGIQIIMQADLALKMGVPIYGIVAMAATATDKIGRSVPAPgkgiLTTAREhhssvkyaspnln 1444 baker's yeast
15801038  209 QVQPFGENSKGVAFAEGFSALLLESAHHRRARQQSEGVRVQTTYTQISAGRSNDASW----LSTNVH------------- 271  Escherichia coli ...
13471256  227 VWQRQGAEGGGVVSGSGGAFLVLEQREHAESRGRKIYAELGPVVSGRARRSRGELD------------------------ 282  Mesorhizobium loti
1E5M_A    285 ---------------------------------------------------------------------------RAIAW 289  Synechocystis sp....
15888910  284 ---------------------------------------------------------------------------KRMER 288  Agrobacterium tum...
17987395  282 ---------------------------------------------------------------------------KTVRE 286  Brucella melitensis
15830544  191 ---------------------------------------------------------------------------KVMQA 195  Escherichia coli ...
15595296  235 ---------------------------------------------------------------------------QAVRA 239  Pseudomonas aerug...
15600367  409 -------------------------------------------------------------------------vaKAVAS 415  Pseudomonas aerug...
15965693  285 ---------------------------------------------------------------------------ARLRY 289  Sinorhizobium mel...
20981695 1445 mkyrkrqlvtreaqikdwvenelealkleaeeipsedqnefllertreihneaesqlraaqqqwgndfykrdpriAPLRG 1524 baker's yeast
15801038  272 ---------------------------------------------------------------------------KVMQA 276  Escherichia coli ...
13471256  283 ---------------------------------------------------------------------------AEIAG 287  Mesorhizobium loti
1E5M_A    290 ALKDSGLKPE-MVSYINAHGTSTPANDVTETRAIKQALGNHAYN----IAVSSTKSMTGHLLGGSGGIEAVATVMAIA-E 363  Synechocystis sp....
15888910  289 LLAPAKDS---AATVVFSGASGYDEVTVREKDILEKVLPNSVIR--------GFGGVTGHGLEAQFPLGLALAALTLE-S 356  Agrobacterium tum...
17987395  287 LVLAANGGK--NPAYVVSGASGAHAATAAEKAALES--VSAAYR--------GISGLTGHLREAQFPLALALGAISVW-K 353  Brucella melitensis
15830544  196 AMKQAEIALD-DLAAILPHGNGSAVSDNAEAKAIAMFAGERQIP------VLAYKGQIGYTATGSGVVDLIIGHHSLThH 268  Escherichia coli ...
15595296  240 ALAEAGCGLE-QMDYRLTDISGEQYYFKEASLTLSRNLR-----------VLKPKFDLWHPADCIGECGAAIGPALLA-- 305  Pseudomonas aerug...
15600367  416 AVQIVGLDTVrHASFVHAHGSSTPANRVTESEILDRVASAFGIDg---WPVTAVKAYVGHSLATASADQLISALGTFK-Y 491  Pseudomonas aerug...
15965693  290 LSKPALELDP-QSTVVFSGTSGFHDLAGREKAFLETELAGRPVR--------AYGGLVGHGIEAQFPVGMVLAALSLG-H 359  Sinorhizobium mel...
20981695 1525 ALATYGLTID-DLGVASFHGTSTKANDKNESATINEMMKHLGRSegnpVIGVFQKFLTGHPKGAAGAWMMNGALQILN-S 1602 baker's yeast
15801038  277 AMKQAEIALD-DLAAILPHGNGSAVSDNAEAKAIAMFAGERQIP------VLAYKGQIGYTATGSGVVDLIIGHHSLThH 349  Escherichia coli ...
13471256  288 LLGAAALPN--GKLLALSGASGAHAATSAEKTALDAN-PAISAR--------GFSTLTGHMKEAQFPFAVALAALAVD-R 355  Mesorhizobium loti
1E5M_A    364 DKVPPTINLENPDP-E---CDLDYVPGQSRALI-VDVALSNSFGFGGHNVTLAFKKYQ 416  Synechocystis sp. PCC 6803
15888910  357 GAKVPTFDAAAEKPmGe-aATEAVVTTVGHVRGeGVAVLSRDV--------------- 398  Agrobacterium tumefaciens str. C58 (Cer...
17987395  354 GEAFAPLDAS-EKPaSg-aVSEAIVTTIGATRAeGAAKLVRA---------------- 393  Brucella melitensis
15830544  269 QLIAPVGNDVIIDSm----ASLVLTDG-SVTNHsKRHLLKVGVGVDGSVIGVVMTNMQ 321  Escherichia coli O157:H7
15595296  306 ------VALAASRK------GYGDGPN-------VFCHLGNDAGERAAALLSYRRVRA 344  Pseudomonas aeruginosa PA01
15600367  492 GILPGIKTIDKVADdVh-qQRLSISNRDMRQDKpLEVCFINSKGFGGNNASGVVLSPR 548  Pseudomonas aeruginosa PA01
15965693  360 AAKVPPFDPAAEAPmLa-pARAAVVTTIGHSRGeGVAVLAAE---------------- 400  Sinorhizobium meliloti
20981695 1603 GIIPGNRNADNVDKiLeqfEYVLYPSKTLKTDG-VRAVSITSFGFGQKGGQAIVVHPD 1659 baker's yeast
15801038  350 QLIAPVGNDVIIDSm----ASLVLTDG-SVTNHsKRHLLKVGVGVDGSVIGVVMTNMQ 402  Escherichia coli O157:H7 EDL933
13471256  356 KAAYPVFDAAAEKPfEg-iPASVLATAIGYHQFeGMALVKST---------------- 396  Mesorhizobium loti
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