Conserved Protein Domain Family
Dcm

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COG0270: Dcm 
Site-specific DNA-cytosine methylase [Replication, recombination and repair]
Statistics
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PSSM-Id: 223348
View PSSM: COG0270
Aligned: 63 rows
Threshold Bit Score: 32.7886
Threshold Setting Gi: 15828656
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024  23 LDNRMTIVLFAGMGGGC-DGLEDAG----FHVHVAINHDPVAVAVHEKRHQH----TRHLRCDVFEADPRKVTGGr-GVR 92
gi 16127856   4 NGQRRFLEFFAGGGMAR-LGLGADW-----ACAFANDFDPVKAATYRANFADa--gKHFQEGDVFALSAERLP----DAD 71
gi 17545588   2 GAYYNEIDPYAAAWLRNlIAAGHIApg-dVDERDIQDVRPEDLRGYKQHHFFa--gVGVWSLALRRAGWPD------DRL 72
gi 15901190   1 --MIWVLDLFAGIGGFR-MGMEAQG----HECLGFCEIDKFARKSYKSIFQTe---GEIEFHDIRDVSDDEFKKLrgKVD 70
gi 730347     4 TKRLRVLELYSGIGGMH-YALNLANi--pADIVCAIDINPQANEIYNLNHG-----KLAKHMDISTLTAKDFDAF--DCK 73
gi 15675067   1 ---MKFLDLFAGIGGFR-LGLINQC----HECIGFCEIDKFARQSYKAIYETe---GEIEFHDIRQVTDQDFRQLrgQVD 69
gi 15838375  14 AAPLLYGSVCSGIEAVS-LAWQPLG----LEAAWFAEIEPFPSAVLAHRYP-----RVPNLGDMTAIARQVRAGtvpAPD 83
gi 17233286   1 --MKSVLSLFSGIGGLChHGIAAAGlshkFQVKQFVEISPYSQSQLRHEQPq----TPIH-SDITTYNCHRG-----QFD 68
gi 17233385   1 --MKSILSLFSGIGGLChHGIAAAGlshkFQVKQFVEISPYSQSRLRHEQPq----TPIH-SDITTYHCHRG-----QFD 68
gi 13476615   5 PEHIDILSLCTGGAGLD-LGVELAIp--sARTVCMVEREAFAVAHLVSAMEQgllhPAPIWSDARTFDGRAWRG---CVD 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024  93 ALHASPDCTHFSVAKGSKPVSKRRRSL--AWVICRWAGTVRP------ETITMENVQEITTWgpliakrdpatgrvlrld 164
gi 16127856  72 LAWASSPCQDFSLAGARAGLAGGRSSA--FFGFWSLMRSLSAegr-apSVIVIENVVGLLTSh----------------- 131
gi 17545588  73 VWTGSCPCQPFSQAGKGLAFADERHLW---PAWYHLISECRP------AVVLGEQVASNNADt----------------- 126
gi 15901190  71 VICGGFPCQAFSIAGRRlgFEDTRGTL--FFEIARAAKQIQPr------FLFLENVKGLLNHd----------------- 125
gi 730347    74 LWTMSPSCQPFTRIGNRKDILDPRSQA--FLNILNVLPHVNNl----pEYILIENVQGFEES------------------ 129
gi 15675067  70 IICGGFSLVKHFHS--QadDWDLRALG--ELSSLRLLERPNR-------------------------------------- 107
gi 15838375  84 ILVGGTPCQSFSVAGSRRGLDDPRGALslAYELANAIDQIRHqdrrspATLVWENVPGVLNDrsna-------------- 149
gi 17233286  69 IVCGGFPCAGTSNSGNRQGLTDPR-----------------P------AIALIENPTGLLYR------------------ 107
gi 17233385  69 IVAGGLPCQGTSNAGNRQGLDDPRSAL--WAEQFRIIESDRP------AIALIENPTGLLYR------------------ 122
gi 13476615  79 GLVGGIPCQPHSLAGKRLGEGDERD----LWSTARRIIVQSGc-----WFVLIENVGGMLSS------------------ 131
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024 165 gsvagkgervpvqeqwlipdpahKGRIWRAWLKHLRGLGYS-------------FEYRVLVCADYGVPTIRKRFFGVAQA 231
gi 16127856 132 -----------------------gGADFTALCQALHEEGYR--------------FGALEIDAGAFVPQSRPRVFVVATR 174
gi 17545588 127 --------------------------WIDLVQDDMEAVGHA-------------FGAVPFPAAGVGAPHIRDRLYWVAYA 167
gi 15901190 126 -----------------------KGRTFTTILTTLDELGFD-------------VEWQVLNSKDFGVPKNRERVFIIGHS 169
gi 730347   130 -------------------------KAAEECRKVLRNCGYN-------------LIEGILSPNQFNIPNSRSRWYGLARl 171
gi 15675067     --------------------------------------------------------------------------------
gi 15838375 150 --------------------fghFLGALAGESRALQPPGDRwahagcvsgprrrIAWRVLDAQYFGVAQRRKRVFLVASG 209
gi 17233286 108 --------------------------GLDQIICDLDSIGy-------------mGGWNCISAQQVGLPHERKRIFII--- 145
gi 17233385 123 --------------------------GLEQIICDLDSIGy-------------mGEWNCISAQQVGLPHQRKRIFII--- 160
gi 13476615 132 -------------------------GGAERVWRDLRRLGFE-------------VEGGLFTAKEVGASHERERFFLLGVA 173
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024 232 DGrpivwpvrthaprkdakrlglkpwvgahtIIDWSLPVKsifgrkKPLAEATLRRTARGVMRyvvdaakpfivpithag 311
gi 16127856 175 NPpgd-----------------------lvgSSAFHTRAVreaaarLPADLQASWVWWGAPSPpa--------------- 216
gi 17545588 168 DGs---------------------------rSRRYSRAVR------RAKAEINREGSEDG-------------------- 194
gi 15901190 170 RKkgtrllfpfrregqatnsetlkalgnlnpSRSGMSGKVyyseglAPTLVRGKGEGFKVAIPcmtp------------- 236
gi 730347   172 -------------------------------NFKGEWSID------DVFQFSEVAQKEGEVKRi---------------- 198
gi 15675067     --------------------------------------------------------------------------------
gi 15838375 210 GDdldpaevlferagllgdscagrapwqeaaHDAGPGAEAagacagLAGFAGLKQPYGKVTTTfgfsggigpvdvaaclm 289
gi 17233286     --------------------------------------------------------------------------------
gi 17233385     --------------------------------------------------------------------------------
gi 13476615 174 DAgrlcle-----------------rwrtagDLVVAASARkiqgqkRQRHGPAAGNGGEVVADag--------------- 221
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024 312 ddrvhdaaeplrtlttahrGEMSVVAPALIRTDQHSAAARngvhsvdepintlhtSSGLAVLGATVVGAGGRAAQSAPRD 391
gi 16127856 217 ------------------rNTDLASMLEPDDRAVWNPPERtaall------almaPSHRAAVEARRAGRERAVGAVFRRM 272
gi 17545588     --------------------------------------------------------------------------------
gi 15901190 237 ---------------drldKRQNGRRFKENQEPMFTLNTQdrygi------vvvgDLPTSFKETGRVYGSEGLSPTLTTM 295
gi 730347   199 -------------------RDYLEIERDWSSYMVLESVLN---------------KWGHQFDIVKPDSSSCCCFTRGYTH 244
gi 15675067     --------------------------------------------------------------------------------
gi 15838375 290 aagpkhdirtetfmvqsvaGSIAHTLDTANNGKGSSEDGTgkgvp------iiafTAQGSGADATLDLTPTLRAGGHRNS 363
gi 17233286 146 -------------------------------------------------------AYPNGLFNSQQPTPWTNQIRNH--- 167
gi 17233385 161 -------------------------------------------------------AYSNGLFNQVVPAPWSNQIGNH--- 182
gi 13476615 222 ------------------rARRPEGTEDVRRRQYQLAGGGq--------------DLEHSKGLRWREGWAETGVRGGRNA 269
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024 392 MLeplgtttgkedrvlvAATLVDTAHGEgmgrgvsewslddPLRTVGasggkavvaasliqsgygeregqaprvldleep 471
gi 16127856 273 RGg-------------eQRAEVRFDGLA-------------GCLRTPrg------------------------------- 295
gi 17545588     --------------------------------------------------------------------------------
gi 15901190 296 QGg-------------dKIPKILIPEPI-------------QFLKVReatkkgy-------------------------- 323
gi 730347   245 LVq-------------gAGSILQMSDHE-------------NTHEQF--------------------------------- 265
gi 15675067     --------------------------------------------------------------------------------
gi 15838375 364 HAnagvvpaiafaqnnrGEVRFESGHGQ-------------VACTVLsngkpgygvpmvacvslrgreqgl-aaelggtv 429
gi 17233286 168 -----------------------IEEVR-------------LSLETR--------------------------------- 178
gi 17233385 183 -----------------------ITQVR-------------LSLETR--------------------------------- 193
gi 13476615 270 IGg-------------aDTAMAHAAIER-------------VGPVSIr-------------------------------- 291
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13477024 472 agtqvggskaalmaaFMAQHNTGEPGRSAEdplstivtlgstqgVVAATLGNLHGTnadgrpivePLATICAGgshahli 551
gi 16127856 296 -------------gsSRQTLLVIDGGEVRSr------------lISPREAARLMGL---------PDSYQLPK------- 334
gi 17545588     --------------------------------------------------------------------------------
gi 15901190 324 ---------aqaeigDSINLERPSSQYRRGr------------vGKGIANTLTTSG---------QMGVVVASy------ 367
gi 730347   266 -------------------ERNRMALQLRY--------------FTAREVARLMGF---------PESLEWSKsn----- 298
gi 15675067     --------------------------------------------------------------------------------
gi 15838375 430 agalrisgggadkpyVLAPDFEAHFRYDWNdpgpgdwshwrvrrLMPVECERLQGM---------PDDYTLIPyrg---- 496
gi 17233286 179 ------------------SYQPGISKVASR--------------ISIGVAKNIPGN---------YDARRAYGl------ 211
gi 17233385 194 ------------------SYQPGISKVASR--------------IPIGVAKNIPGN---------YDARRAYGl------ 226
gi 13476615 292 --------------sRRQVKADTHADRPGLfp----------pgPTDIEAWRNVLGrap---qlePAVRRMADgv----- 339
                       570       580       590       600       610
                ....*....|....*....|....*....|....*....|....*....|
gi 13477024 552 lgflqhyfgsgkQDDDVRQPLGAlt--gKARYGLVEVMVKGVRHYIDDIG 599
gi 16127856 335 ------------SQTAGLQVMGD-----GVAVPVVRWLAETLLVPLVDSK 367
gi 17545588     --------------------------------------------------
gi 15901190 368 -----------eGEDKQVYQVAGvlidgQFYRLRIRRITPKECFRLHGFP 406
gi 730347   299 -----------vTEKCMYRLLGN-----SINVKVVSYLISLLLEPLNF-- 330
gi 15675067     --------------------------------------------------
gi 15838375 497 ---------kpaADAPRYKAIGN-----SMAVPCMAWLGQRLVQYLHKTG 532
gi 17233286 212 ------------SCSPRQAAVAW-----KRIDYLCSLLFEKEAS------ 238
gi 17233385 227 ------------SCSPRQAAVAW-----KRIDYLCSLLSYQEAS------ 253
gi 13476615 340 -----------aARVDRLRMLGN-----GVVSLEAAYALRTLATRLAGQG 373
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