Conserved Protein Domain Family
TrpS

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COG0180: TrpS 
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
Statistics
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PSSM-Id: 223258
View PSSM: COG0180
Aligned: 72 rows
Threshold Bit Score: 269.06
Threshold Setting Gi: 19074853
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15791034  73 RNDEPFAALSGFMPTGd-PHIGHKMVFDELIWHQQQG-GDAYALIADLEAHSARGLDWAEIDEHA-EDYLLSLLALGFDA 149
gi 19074853  76 ANNRPFYLYTGRGPSSktMHIGHTIPFLLCKYMQDAFkIRLVIQITDDEKFLWKS-MRLEDAMAYgRENIKDIVALGFDP 154
gi 20093781  58 NDGKLVSVLSGMMPSGr-MHLGHKTVVDQLVFYQQEMdVKVYVPIADLEAHHARNMDLDRAHRIAvEEYVLNYAALGLDL 136
gi 3122904   57 KKGEDFAVVTGMMPSGr-MHIGHKMIVDQLRWYDRMG-AEIFIPIADMEAYSARGVDFEDSRRIAiEEYIAGYIALGLDL 134
gi 17367824  69 EEGRGFFLYTGRGPSGp-MHIGHIIPFFATKWLQEKFgVNLYIQITDDEKFLFKENLTFEDTKHWaYENILDIIAVGFDP 147
gi 20178127  68 GEGRPWALYTGRGPSGp-VHIGHMVPWILLKWFSDKFgLEVYFQITDDEKFYDDPEMKLEEATNWaYENALDVIALGFSP 146
gi 14591663   1 ------------------MHIGHIIPFFATKWLQEKFgVNLYIQITDDEKFLFKENLTFDDTKRWaYDNILDIIAVGFDP 62
gi 1174553   78 EQKKPFYLYTGRGPSSdsMHLGHMIPFMFCKWLQDVFqVPLVIQLTDDEKFLFKQGVSLEDCQRFaRENAKDIIAVGFDP 157
gi 15897383  74 EKSKGFFLYTGRAPSLg-MHIGHLIPFIFTKWLQEKFnANLYIEITDDEKYMRNPEFTLDQTRSWaYDNILDIIAVGFNP 152
gi 2501074   98 EQGKPFFLYTGRGPSSdsMHLGHMIPFVFTKWLQEVFdVPLVIELTDDEKFLFKHKLTINDVKNFaRENAKDIIAVGFDP 177
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15791034 150 DE--GELYRQSTNRE--LQDLAFELGIEANTSEFEAIYGFGGDTDVSHMQSVVTQMADILYPQLdap-------kpTVIP 218
gi 19074853 155 KL--TYIFSNVEASh-hFEENILKISKTINLNEAIKVFGFDMSSNIGQVGFPAKEIAPCFS-SSfrfig---kgamCLVP 227
gi 20093781 137 DPdrCEIYLQSERKT--VQRMALLLAGRLTWNTVKNTYGFTGETNMGHAFAPIVQAADILHPQeieg------phrVLVP 208
gi 3122904  135 EKdnIHVYLQSENLM--VEDLAYVLAGKVNFNELRAIYGFTGSTSMAHMYAPIIQVSDILHPQLdelg----gprpVIVP 208
gi 17367824 148 DK--TFIFQNSEFTK--IYEMAIPIAKKINFSMAKAVFGFTEQSKIGMIFFPAIQIAPTFF--Ekr---------rCLIP 212
gi 20178127 147 ER--LHLIIDTKDIKp-LYPIAVRVAKKLTWNTVKATFGFTDSTNIGLIFYPSLQIAVAFLPTElrre-----atpVLIP 218
gi 14591663  63 DK--TFIFQNSEFTK--IYEMAIPIAKKINFSMAKAVFGFTEQSKIGMIFFPAIQIAPTFF--Erk---------rCLIP 127
gi 1174553  158 KK--TFIFMNSTYVGgaFYQNVVRIAKCITANQSKACFGFTDSDSIGKIHFASIQAAPSFS-SSfphifngakdipCLIP 234
gi 15897383 153 DK--TFIFQDTEYIRn-MYPITVKIAKKLTFSEVRATFGLDASSNIGLIFYPALQIAPTMF--Ekk---------rCLIP 218
gi 2501074  178 KN--TFIFSDLQYMGgaFYETVVRVSRQITGSTAKAVFGFNDSDCIGKFHFASIQIATAFP-SSfpnvlglpdktpCLIP 254
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15791034 219 VGPDQDPHVRFARDLAERTRyfkvteafasvafddderplvraaydarsqyaadtdqprcteaadwlaaepaaadgvdaa 298
gi 19074853 228 AAVDQDPFFRLARDKAKALG------------------------------------------------------------ 247
gi 20093781 209 VGVDQDPHLRLTRDIAEKE------------------------------------------------------------- 227
gi 3122904  209 VGPDQDPHIRLTRDIAarfr------------------------------------------------------------ 228
gi 17367824 213 AAIDQDPYWRLQRDFAESLG------------------------------------------------------------ 232
gi 20178127 219 CAIDQDPYFRLARDIADALG------------------------------------------------------------ 238
gi 14591663 128 AAIDQDPYWRLQRDFAESLG------------------------------------------------------------ 147
gi 1174553  235 CAIDQDPYFRLTRDVSGRLK------------------------------------------------------------ 254
gi 15897383 219 AGIDQDPYWRLQRDIAESLG------------------------------------------------------------ 238
gi 2501074  255 CAIDQDPYFRVCRDVADKLK------------------------------------------------------------ 274
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15791034 299 taesvvqklenagmeplrprvrffdrqatdeaftalideiagekrvfeghvdafelsaetardlalavevdhggyGFVPP 378
gi 19074853 248 ----------------------------------------------------------------------------EKKP 251
gi 20093781 228 ---------------------------------------------------------------------------DLIKP 232
gi 3122904  229 ------------------------------------------------------------------------drygFILP 236
gi 17367824 233 ----------------------------------------------------------------------------YYKT 236
gi 20178127 239 ----------------------------------------------------------------------------YPKP 242
gi 14591663 148 ----------------------------------------------------------------------------YYKT 151
gi 1174553  255 ----------------------------------------------------------------------------FKKP 258
gi 15897383 239 ----------------------------------------------------------------------------YYKA 242
gi 2501074  275 ----------------------------------------------------------------------------YSKP 278
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15791034 379 SSVYHRFMTGLTG--GKMSSSEPASHISLLDDPETGADKVAA-ATTGgrDTAAEQRErGGEPDDCPVYELYAYLLAg--D 453
gi 19074853 252 SSIYVSLLPDLKGvnRKMSASDPNSSIYLDDAQDTIRKKIIAyAYSGgrKTLEEHREkGGDIDVDVPFEY-LKYFLd--D 328
gi 20093781 233 ASTYHRFMTGLTG--GKMSSSKPNTAIFLTDDPETAKEKVWN-AKTGggATLEEHREhGGNPDECVVYELMVYHLAdriG 309
gi 3122904  237 SSTYHRFMGGLTG--GKMSSNRPKSAIFLSDTPEEAEAKIRN-AKTGgrETLKEQRElGGVPEECIIYETLLYHMSg--S 311
gi 17367824 237 AAIHSKFVPSLTSlsGKMSASKPETAIYLTDSPEDVEKKVWKfALTGgrPTLKEQREkGGEPEKCVVFKWLEIFFEe--D 314
gi 20178127 243 STLYSKFIMALTGe-SKMSASNPDSAIYTLDDEKTVRRKVMN-AFTGgrPTAEEQRKyGGNPEVCPVFHY-HMLFDp--D 317
gi 14591663 152 AALHSKFVPSLTSlsGKMSASKPETAIYLTDSPEDVEKKVWKfTLTGgrPTLKEQREkGGEPEKCVVFKWLEIFFEe--D 229
gi 1174553  259 ALLHSRFFPALQGpqSKMSASKDSSAIFMTDTPNKIKNKINRhAFSGggATIEIHREkGGNPDVDVAYQY-LSFFLd--D 335
gi 15897383 243 AQIHSKFLPPLTGpeGKMSSSNPETAIYLVDDPKTVERKIMKyAFSGgqPTIELHRKyGGNPEIDVPFQWLYYFFEe--D 320
gi 2501074  279 ALLHSRFFPALQGstTKMSASDDTTAIFMTDTPKQIQKKINKyAFSGgqVSADLHRElGGNPDVDVAYQY-LSFFKd--D 355
                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15791034 454 DDALaeEVYAECANGDRLCGGCKEQAADLMAQFLETHQENREAARDVLaELDIDL--DSARV 513
gi 19074853 329 DQELe-KYRSGYIKGEITSKEMKEKCVVVIQEFVSRYQESRKRVTDDDlRAFIDIn-KF--- 385
gi 20093781 310 GDEKlrEIRKKCREGDIICGECKRMVGEALAEILEELERRREDVRDELpDLLSQH--PDAPE 369
gi 3122904  312 DSRLe-EIYESCRNGTLMCGECKNNTAEFIRKFFEELSVKREKA--LPaARRILE--G---- 364
gi 17367824 315 DKKLk-ERYYACKNGELTCGECKRYLISKIQEFLKEHQKRRKKAEKQIeKFKYTG--KLAQE 373
gi 20178127 318 DASVe-KIRQDCKSGALLCGECKLKLHEKITKFLKEHRERREKARGKVdEYRLSV--KLSK- 375
gi 14591663 230 DKKLk-ERYYACKNGELTCGECKRYLISKIQEFLKEHQRRRKKAEKLVeKFKYTG--KLAQE 288
gi 1174553  336 DEKLk-QLYNTYKAGTLSTGEMKGECIKLLQQFVSDFQAARSKVDEATlDMFMDGsrKLEW- 395
gi 15897383 321 DNRIk-EIEEEYRSGKMLTGELKQILIDKLNNFLEEHRRRREEAKELVhVFKYDG--KLAKQ 379
gi 2501074  356 DVFLk-ECYDKYKSGELLSGEMKKLCIETLQEFVKAFQERRAQVDEETlDKFMVPh-KLVWG 415
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