Conserved Protein Domain Family
GalK

?
COG0153: GalK 
Galactokinase [Carbohydrate transport and metabolism]
Statistics
?
PSSM-Id: 223231
View PSSM: COG0153
Aligned: 24 rows
Threshold Bit Score: 350.452
Threshold Setting Gi: 19553434
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
585166    21 LPRPLAEKCPSIIKKFISAydAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNpsITLINADPKF 100 baker's yeast
12643843   6 ENSTVLSALTEKFAEVFGD--TKEVEYFFSPGRINLIGEHTDYNGGYVFPASITIGTTGLARLREDKK--VKLYSENFPK 81  Lactococcus lactis ...
6225404    1 -----------------------MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTG-----AITARSDR 52  Mycobacterium tuber...
6225404    1 -----------------------MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTG-----AITARSDR 52  Mycobacterium tuber...
18312461   1 ---------------------MEALVKASAPGRLDFLNTHQDYKGLPVVSVAVNMRTRVEMEASKVFE----IESLNTG- 54  Pyrobaculum aerophilum
11132107   1 ---------------------MIKVK---SPGRVNLIGEHTDYTYGYVMPMAINL--YTKIEAEKHGE--VILYSEHFGE 52  Pyrococcus horikoshii
15901681   2 AQHLTTEALRKDFLAVFG---QEADQTFFSPGRINLIGEHTDYNGGHVFPAAISLGTYGAARKRDDQV--LRFYSANFED 76  Streptococcus pneum...
21759136  15 NPKENKARYAKLLNSFEQKyhCKPDFFSRSPGRVNIIGEHIDYNYFSVLPMAIDVDVIVSVTTSDDAK--VELNNTNPEF 92  fission yeast
6831547    1 ----------------------MKVK---APGRINIIGEHTDYNDGYVLPFAVNR--YVFLSIEGSER--FIFHSENVNE 51  Thermotoga maritima
11132161   6 NTLAMMLRMQRVESCHTEEygDEPEAIAVVPGRFHLLGEYLWFAQGNTLSMAIDQTLTLCVSRRKDST--FRLFSLTLGE 83  Treponema pallidum
585166   101 AQRKFDLPLDGSYVTIdpsvSDWSNYFKCglhvaHSFLKKLAPERFAsap--laGLQVFCEGDVPTGSGLSSSAAFICAV 178 baker's yeast
12643843  82 LGVIEFDLDEVEKKDG----ELWSNYVKG-----MIVMLKGAGYEIDk------GFELLIKGEIPTASGLSSSASLELLV 146 Lactococcus lactis ...
6225404   53 ADGSARIPLDTTPGQV----TGWAAYAAG-----AIWALRGAGHPVP-------GGAMSITSDVEIGSGLSSSAALIGAV 116 Mycobacterium tuber...
6225404   53 ADGSARIPLDTTPGQV----TGWAAYAAG-----AIWALRGAGHPVP-------GGAMSITSDVEIGSGLSSSAALIGAV 116 Mycobacterium tuber...
18312461  55 -EKCIFQDPQIAGR-------TFCDYVKA-----AVLALWKHGVYLR-------GFKSVVRSDIPIGAGMASSAALLVSL 114 Pyrobaculum aerophilum
11132107  53 ER--KFSLNDLRKE------NSWIDYVKG-----IFWVLKESDYEVG-------GIKGRVSGNLPLGAGLSSSASFEVGI 112 Pyrococcus horikoshii
15901681  77 KGIIEVPLADLKFEKE----HNWTNYPKG-----VLHFLQEAGHVIDk------GFDFYVYGNIPNGAGLSSSASLELLT 141 Streptococcus pneum...
21759136  93 KEEILELPSDGAVIEInkthHTWGNYFRCsmivaHKYILEKYPELVSggkkplkGLKLIFDGNVPTGGGLSSSAAFCVAS 172 fission yeast
6831547   52 T----VEMEKIEKL------NKWTDYISG-----VIASFEKRGYRVS-------PVKISVSSNLPIGAGLSSSAALEVAT 109 Thermotoga maritima
11132161  84 RRKISTANLRYRKE------DRWANSVKA-----VILSFMDGGYHLT-------GLNCTILSQIPPDAGLGTPNALKVAM 145 Treponema pallidum
585166   179 ALAVVKANmgpGYHMSKQNLMRITVVAE-HYVGVNNGGMDQAASVCGEEDHALYVEFKpQLKATPFKFPQLKnheISFVI 257 baker's yeast
12643843 147 GVVLDDLF---NLNVPRLELVQLGQKTEnDYIGVNSGILDQFAIGFGEVKKAILLDCN-TLKYEMVPVELRD---YDIVI 219 Lactococcus lactis ...
6225404  117 LGAVGAAT---GTRIDRLERARLAQRAEnDYVGAPTGLLDHLAALFGAPKTALLIDFR-DITVRPVAFDPDAc-dVVLLL 191 Mycobacterium tuber...
6225404  117 LGAVGAAT---GTRIDRLERARLAQRAEnDYVGAPTGLLDHLAALFGAPKTALLIDFR-DITVRPVAFDPDAc-dVVLLL 191 Mycobacterium tuber...
18312461 115 IAAALRLA---NREADRATVAELAYVAErEILGVPCGRLDQYGSAFG---KVAVIHPKpPVRVEALEMPGG-----VFVV 183 Pyrobaculum aerophilum
11132107 113 LETLDKLY---NLKLDSLSKVLLAKKAEnEFVGVPCGILDQFAVVFGREGNVIFLDTH-TLDYEYIPFPKD----VSILV 184 Pyrococcus horikoshii
15901681 142 GVVAEHLF---DLKLERLDLVKIGKQTEnNFIGVNSGIMDQFAIGMGADQRAIYLDTN-TLEYDLVPLDLKD---NVVVI 214 Streptococcus pneum...
21759136 173 ILAILKANg-iN-TITKEDLVKISVVSE-HYVGVNTGGMDQCASIYGEQNKALLVQFKpKLMATPFKMPVLKphdMVFLI 249 fission yeast
6831547  110 AYAISEYF---GFNVPKLELVKIAREAEvEFVGVRCGIMDQFTAVFGKKDHAIFLDTM-TLEYEYVPLKLEG---YEINL 182 Thermotoga maritima
11132161 146 ALVLGRLF---AATLPKESVVSIVEHANeRYLKTHAHRADILCVLFAKQGSCVRTDHR-KKQAELCQFPSEG---KRIVL 218 Treponema pallidum
585166   258 ANTLVvsnKFETAPTNYNLRVVEVTTAANVLAAtYgvvllsgkegsstnKGNLRDFMNVYYARYHNISTPwNGdiesgie 337 baker's yeast
12643843 220 MNTNK---PRALTESKYNERFAETREALKRMQT-Rl------------dIQSLGELSNEEFDANTDLIGD--E------- 274 Lactococcus lactis ...
6225404  192 MDSRA---RHCHAGGEYALRRASCERAAADLGV-----------------SSLRAVQDRGLAALGAIA---DP------- 241 Mycobacterium tuber...
6225404  192 MDSRA---RHCHAGGEYALRRASCERAAADLGV-----------------SSLRAVQDRGLAALGAIA---DP------- 241 Mycobacterium tuber...
18312461 184 LDSGV----RHSTAEVHSKRQAELQQAVEMLKAeLgi-----------ySEGYWDFPWGVLYDKPNAVEK-LP------- 240 Pyrobaculum aerophilum
11132107 185 FYTGV---RRELASSEYAERKHIAEESLKILGK-----------------GSSKEVREGELSKLPPLHR----------- 233 Pyrococcus horikoshii
15901681 215 MNTNK---RRELADSKYNERRAECEKAVEELQV-Sl------------dIQTLGELDEWAVDQYSYLIKD--E------- 269 Streptococcus pneum...
21759136 250 SNTLVeanKQETALTNYNLRVVEMAVASEFLAKkFnlelpk---esnlhTGTLRGFMDEYYEKHLKQPHw-DGsdidmgv 325 fission yeast
6831547  183 VDSNV---KHELSSSEYNRRRQECEEVLKTLEK-----------------KSFREVTKEDLERLSGTLR----------- 231 Thermotoga maritima
11132161 219 TDSRV---PRFIAREEFTARLKRCVDAYELVKR----------------NPDMPRAMSKLMAAALEEIDVpEG------- 272 Treponema pallidum
585166   338 rltkmlvlveeslankkqgfsv--ddvaqslncsreeftrdylttspvrfqvlKLYQRAKHVYSESLRVLKAVKLMttas 415 baker's yeast
12643843 275 -----------------------------------------------------TLIKRARHAVYENNRTKIAQKAF---- 297 Lactococcus lactis ...
6225404  242 -----------------------------------------------------IDARRARHVLTENQRVLDFAAAL---- 264 Mycobacterium tuber...
6225404  242 -----------------------------------------------------IDARRARHVLTENQRVLDFAAAL---- 264 Mycobacterium tuber...
18312461 241 -----------------------------------------------------SPLRERVLFTLEMQRSTERALAYlk-r 266 Pyrobaculum aerophilum
11132107 234 --------------------------------------------------------KFFGYIVRENARVLEVRDAL---- 253 Pyrococcus horikoshii
15901681 270 -----------------------------------------------------NRLKRARHAVLENQRTLKAQVAL---- 292 Streptococcus pneum...
21759136 326 qrmqemlrlteimfseeqkvgfkteelakelglsveeftkvfltkipvkyermKIYQRTVHVYSDAMRVLQVLKLFhqhk 405 fission yeast
6831547  232 --------------------------------------------------------KRAQHVLEENERVLKSVQAL---- 251 Thermotoga maritima
11132161 273 ------------------------------------------------------IRRRVISLVRESLGVDEAIEAL---- 294 Treponema pallidum
585166   416 FTADed-fFKQFGALMNESQASCDKLYECSCPEIDKICSIALSNGS------YGSRLTGAGWGGCTVHLVpggPNGNIEK 488 baker's yeast
12643843 298 VAGN----LTKFGELLNASHASLKDDYEVTGLELDTLAETAQKQAGv-----LGARMTGAGFGGCAIALV---AHDNVSA 365 Lactococcus lactis ...
6225404  265 ADSD----FTAAGQLLTASHESMREDFAITTERIDLIAESA-VRAGa-----LGARMTGGGFGGAVIALV---PADRARD 331 Mycobacterium tuber...
6225404  265 ADSD----FTAAGQLLTASHESMREDFAITTERIDLIAESA-VRAGa-----LGARMTGGGFGGAVIALV---PADRARD 331 Mycobacterium tuber...
18312461 267 RDLPteeiLRKVGAEMLLQHRLLSELYDVSLPELDRLVEEAVNAGA------YGAKLSGAGLGGVVIALA---PNR---E 334 Pyrobaculum aerophilum
11132107 254 KEGN----VEEVGKILTTAHWDLAKNYEVSCKELDFFVERAL-KLGa-----YGARLTGAGFGGSAIALV---DKEDAET 320 Pyrococcus horikoshii
15901681 293 QAGD----LETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEGv-----LGARMTGAGFGGCAIALV---QKDTVEA 360 Streptococcus pneum...
21759136 406 DSDDpqkfMLAFGRLLNDSQRSEDIYNNSSSPELREVCKISLANGG------YGARTTGAGWGGSAVHLT---THDKLAK 476 fission yeast
6831547  252 KEGD----FETLGKLLFSSHESLRDLYEVSCEETDFIVDYLRGKEGi-----LGARMVGGGFGGGVIVLS---KKGAFGK 319 Thermotoga maritima
11132161 295 RKRD----FAAFSRVVNRSHERLRDRFEISCPELDWLVKRALEFVDpdapdvVCSRLTGRGFGGCTYAIL---RDQDFEP 367 Treponema pallidum
585166   489 VKEALANEFYKVKYpkitdaeLENAIIVSKPALGSCLYE 527 baker's yeast
12643843 366 FEKAVGQVYEEVVG-------YPASFYVAQIGSGSTKLD 397 Lactococcus lactis subsp. lactis
6225404  332 VADTVR-RAAVTAGy------DEPAVSRTYAAPGAAECR 363 Mycobacterium tuberculosis
6225404  332 VADTVR-RAAVTAGy------DEPAVSRTYAAPGAAECR 363 Mycobacterium tuberculosis
18312461 335 TAEKIGRRSSAVKW------------WAVEVDEGLKYGD 361 Pyrobaculum aerophilum
11132107 321 IGEEILREYLKRFP-------WKARHFIVEPSDGVG-I- 350 Pyrococcus horikoshii
15901681 361 FKEAVGKHYEEVVG-------YAPSFYIAEVAGGTRVLD 392 Streptococcus pneumoniae TIGR4
21759136 477 LVEALTEQYYKKQFpkitqseLNAAVVVSKPAAGSCIVQ 515 fission yeast
6831547  320 IKEELVESYRKRFG-------IDLIFHEIESSDGVQKI- 350 Thermotoga maritima
11132161 368 YLERLD-EYERIFG-------FKAAAYEVQCSEGARVL- 397 Treponema pallidum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap