Conserved Protein Domain Family
zf_UBZ
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pfam18439: zf_UBZ (this model, PSSM-Id:465769 is obsolete and has been replaced by 465769)
Ubiquitin-Binding Zinc Finger
This is ubiquitin-binding zinc finger (UBZ) domain found in DNA polymerase eta (EC:2.7.7.7). It is important in the recruitment of the polymerase to the stalled replication machinery in translesion synthesis. The UBZ domain adopts a classical C2H2 zinc-finger structure characterized by a beta-beta-alpha fold.
Links
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Statistics
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PSSM-Id: 465769
Aligned: 72 rows
Threshold Bit Score: 38.6448
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_011122001 665 TAFPCSRCNNKLIPLdKLDEHSDWHFAKDLLQE 697
OWR51403     715 ETKLCAECGKKVPIN-KLPEHLDFHEAQKLSRE 746
XP_001845071 644 TTKPCPECGKNVPEH-TLQSHLDFHVALRISQQ 675
XP_971192    528 ETELCSECKKRIPIS-ELMSHQDYHFALNLSRS 559
KFB45372     671 VTVDCQQCGKQIPEN-EYLSHQDFHFALSLSQQ 702
XP_007545334 675 DLITCERCGKEVLVW-ELPEHNDFHFALDLQTS 706
ESO02571     532 DNITCDKCGHVISAW-DFPEHEDYHYACQLQRQ 563
VDL63701     526 DTILCEECGLQIPVH-IMPEHSDFHLARKLQAE 557
VDM23462     228 EKVLCADCGSYVLMH-LMPEHQDFHFARKVQQE 259
VDL95661     547 NTIICEECGARVLIH-LMSEHTDFHVAHRIQQE 578
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