Conserved Protein Domain Family
PPARgamma_N
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pfam12577: PPARgamma_N (this model, PSSM-Id:463633 is obsolete and has been replaced by 463633)
PPAR gamma N-terminal region
Peroxisome proliferator-activated receptors (PPAR) are nuclear hormone receptors that control the expression of genes involved in lipid homeostasis in mammals. This sequence region is found at the N-terminus of these proteins. The family is found in association with pfam00104, pfam00105. It is not clear if this region is a separate protein domain.
Links
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Statistics
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PSSM-Id: 463633
Aligned: 8 rows
Threshold Bit Score: 102.181
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
POI35150       1 MVDT-EMPFWPVNFGISPVDLSAMDDHMHSFDIKPFTTVDF----------------------SSIS------------- 44 
XP_003217721   1 MVDT-EMPFWPMNFGISPVDLSAMDEHSHSFDIKPFTTVDF----------------------SSLS------------- 44 
XP_003462784   1 MVDT-EMPFWPTNFGLSSMDLSVMDDHSHSFDIKPFTTVDF----------------------SSIS------------- 44 
XP_006004475   1 MVDT-QMPLWSMNFGLSSVDLTDLDDHSHSFDIKPFTTVDF----------------------SSIS------------- 44 
AKG51674       1 MVDTqQLLAWPVGFSLSTVDLPEFNDSSHCLDMKHLSTSDY----------------------ASISsssipsslspplv 58 
KAA8593290     1 MVDTqQLLAWPVGFSLSAVDLSELDDSSHSLDMKHLSTLDYasissssipsslspplvssissA---------------- 64  orangethroat da...
XP_006631094  23 MVDT-QMPVWPMNFGLNAVDLADLDDSSQSFDMKPFTTVDY----------------------SSIS------------- 66  spotted gar
CAG07050      46 MVDTqQLLAWPVGFSLNSMDLPELYDHPHSLDMKHLTTLDY----------------------TSISssstqssmspsfv 103 spotted green p...

POI35150      45 ------SPHYEDIP-LGRADQTSIDY--KYDIKLQd-cQSAIKL 78 
XP_003217721  45 ------SPHYEDLA-LARTDQMAIDY--KYDVKFQe-cQNTIKL 78 
XP_003462784  45 ------TPHYEDIP-FPRVDPMVADY--KYDLKLQe-yQNAIKV 78 
XP_006004475  45 ------SMHYEHSP-LSGIDQTTTDY--EYDLRIPe-yQYAVKt 78 
AKG51674      59 ssmsstGMAYDPSPpQSEDHLTNMDYtnLHSYRTEldthSSVKL 102
KAA8593290    65 ------GVAYDPSPpQNDEQLTNMDFtnMHSYRMEpdthNLIKL 102 orangethroat darter
XP_006631094  67 ------SLAYETSP-LPSEDLAQFDY--MYDFKMNe-nPNTIKM 100 spotted gar
CAG07050     104 acisptDMGYDPSPpLSEEHMTGMDYlnMHGC-------NSIKL 140 spotted green pufferfish
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