Conserved Protein Domain Family
SOXp

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pfam12336: SOXp (this model, PSSM-Id:463537 is obsolete and has been replaced by 463537)
SOX transcription factor
This domain family is found in eukaryotes, and is approximately 80 amino acids in length. The family is found in association with pfam00505. There are two conserved sequence motifs: KKDK and LPG. This family is made up of SOX transcription factors. These are involved in upregulation of nestin, a neural promoter.
Statistics
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PSSM-Id: 463537
Aligned: 14 rows
Threshold Bit Score: 52.9532
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_017265803 104 YRPRRKTKTLLKKDKYS-LAGGLLSG-----------PSAGGGVGLsvgmsssGVG--------QRLEspgghggsagsG 163
Q9PT76       104 YRPRRKTKTLLKKDKYS-LPGGLLAP-----------GANAVNNSV-------SVG--------QRMD-----------G 145 Japanese medaka
Q68FA4       109 YRPRRKTKTLLKKDKYS-LPGNLLAP-----------GVSPVASSV-------GVG--------QRID-----------T 150 tropical clawed...
EOA97618     108 YRPRRKTKTLMKKDKYT-LPGGLLAP-----------GTNTMTTGV-------GVGatlgagvnQRMD-----------S 157
Q6NVN0       106 YRPRRKTKTLMKKDKYT-LPGGLLAP-----------GANPMTS---------GVGaslgagvnQRMD-----------T 153 tropical clawed...
Q9Y0D7       130 YRPRRKTKTLLKKDKFT-LPGIINPQ-----------TGAPVQRGVgdg----------------------------mhG 169 purple sea urchin
EEN49032      80 YRPRRKTKTLMKKDKYS-LPGGLIAA-----------NGAPVQRTIatg----------------------------mdQ 119
3_pfamImport   1 YRPRRKTKTLMKKDKYP-LTTGSLIPnnsvdparssaNNTGVQQVVsr------------------------------dm 49 
XP_002592066  87 YRPRRKLKTMMKNSSFPtMPGGMPPNyfpa---sncsPPPALQMSMp-------------------------------eQ 132
NP_001306894 108 YRPRRKTKTLMKKDKYA-LPGGLLAP-----------GGGGVGVGVgv---gvGVGsgvgagmnQRMD-----------G 161
XP_017265803 164 YAHMNGWA-NGAYsgqvaaaaaaaAMMQEaQLAYSQHPGSGAhhhhhshhhhsHNPQPM-HRY 224
Q9PT76       146 YAHMNGWT-NSAY-----------SLMQD-QLAYPQHPSMNS-----------PQIQQM-HRY 183 Japanese medaka
Q68FA4       151 YAHMNGWT-NGAY-----------SLMQD-QLGYSQHPGMNS-----------PQMQQIqHRY 189 tropical clawed frog
EOA97618     158 YAHMNGWT-NGGY-----------GMMQE-QLGYPQHPGLNAhn--------aAQMQPM-HRY 198
Q6NVN0       154 YAHMNGWT-NGGY-----------GMMQE-QLGYPQHPGLSAhn--------aPQMQPM-HRY 194 tropical clawed frog
Q9Y0D7       170 YQHLNGYM--NGYp----------SMMQD-QLSHLPSHSYGAhqa------aqMANSGLhHRY 213 purple sea urchin
EEN49032     120 YAHMNGYMsNNAYt----------HMMHQdQLHAYPHPGISPaqta----sqmASNASLpPRY 168
3_pfamImport  50 YQMPNGYM-PNGY------------MMPDp-SAYQQHTAYSSh------------mASGyPRY 86 
XP_002592066 133 YGHMNGYM--SGYh---------sSMMRDpANPYSHQVIPSSaa--------aTTAGSMpTRY 176
NP_001306894 162 YAHMNGWS-NGGY-----------GMMQD-QLGYAQHAGLNApm-------qtSATAPV-HRY 203
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