7AOD


Conserved Protein Domain Family
RNA_pol_Rpa2_4
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pfam06883: RNA_pol_Rpa2_4 (this model, PSSM-Id:462028 is obsolete and has been replaced by 462028)
RNA polymerase I, Rpa2 specific domain
This domain is found between domain 3 (pfam04565) and domain 5 (pfam04565), but shows no homology to domain 4 of Rpb2. The external domains in multisubunit RNA polymerase (those most distant from the active site) are known to demonstrate more sequence variability.
Links
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Statistics
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PSSM-Id: 462028
Aligned: 116 rows
Threshold Bit Score: 55.183
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7AOD_B            568 VGWCTYK-LAKHVADVLRLMKIEyavk-----------lrnGtAtepAKVPLDLEIGYVPPS-H--NGQYPGLYLFSNPA 632  Schizosac...
EFH69848          583 VGTLSSN-LVTKVVSYLRRLKVE------------------A-P---SVIPEDLEVGYVPIS-M--GGSYPGLYLASCPA 636 
XP_003056556      599 VGFMRAA-DSAKVVATLRSAKVS------------------E-P---PKVPPSLEVVYIPTLvNrsGGAFPGLYLFTSSS 655 
XP_002507157      579 LGFVADS-DAKVVVSALRAAKVS------------------G-S---NGVSSHLEIAHIPLSsCgyGGAFPGLYLFSTSS 635 
EFN59491          552 VGHVRAS-LAGAMVAHLRAIKAAslaaeeqltpgatlvplhDeE---MSVPSHAEVVHIPYE-R--GAPYPGIFIFTQAR 624 
Q4E4P5            951 LGYLAPE-EAERVCKALLRKKALktgssmelsgivrrhsvnAfS--------MVEVVYVPPG----NKDPQGLYIFYDNG 1017 Trypanoso...
XP_001565714      923 LGYLSPT-DAMKAAATLRQLKALtlrsqvhvsgivrrkdasPlH--------TLEVVYVAPG----SRDPAGLYVFYDCG 989 
Q387I8            956 LGYLSPN-EALSASKALTQKKALrsrgvvgvtgivrrdsisSlN--------TMEVVYIPPG----SKDPMGLYIFYQYG 1022 Trypanoso...
XP_001708931      577 LGYLDTNeRAIQLVACIRAAKVK------------------------SIIFPYTEVVFIEKGnK--DHLFPGIYMNTSMG 630 
jgi:OSTLU_119522  573 VGYISAE-NASHVISALRAFKVT------------------L-T---TSVLRMSEISYIHPGgE--HGLFPGLYIFYGPS 627 

7AOD_B            633 RMVR 636  Schizosaccharomyces pombe 972h-
EFH69848          637 RFIR 640 
XP_003056556      656 RLMR 659 
XP_002507157      636 RMMR 639 
EFN59491          625 TPGR 628 
Q4E4P5           1018 RMMR 1021 Trypanosoma cruzi
XP_001565714      990 RLMR 993 
Q387I8           1023 RLMR 1026 Trypanosoma brucei
XP_001708931      631 RFYR 634 
jgi:OSTLU_119522  628 RLMR 631
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