6RYR


Conserved Protein Domain Family
CHDII_SANT-like
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pfam06461: CHDII_SANT-like (this model, PSSM-Id:461920 is obsolete and has been replaced by 461920)
CHD subfamily II, SANT-like domain
CHD proteins (name derived from the presence of a Chromodomain, SWI2/SNF2 ATPase/Helicase and a motif with sequence similarity to a DNA)binding domain) are ATP-dependent chromatin remodelers found in plant and animals. In eukaryotes, there are three subfamilies, I, II and III. This domain is found in members of subfamily II which play a role in repression of genes involved in developmental regulation, including Mi-2 from Drosophila melanogaster, CHD3/4/5 from animals and PICKLE (a CHD3/4-related protein) from Arabidopsis. Sequence analysis revealed that this domain has a considerable similarity to SANT domains suggesting that it fold into this type of domain and it is integral to the DNA binding domain of CHD remodelers in subfamily II.
Links
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Statistics
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PSSM-Id: 461920
Aligned: 15 rows
Threshold Bit Score: 218.392
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6RYR_W       1396 SEAPRRP-SRKGLRnDKDKPL-PpLLARVGGNIEVLGFNARQRKAFLNAIMRYGMppqDAFTTQWLVRDLRGKSEKEFKA 1473
Q9S775        920 VQTGRRP-YRRKGR-DNLEPT-P-LMEGEGRSFRVLGFNQSQRAIFVQTLMRYGA---GNFDWKEFVPRLKQKTFEEINE 992  thale cress
XP_002515445  932 TQSGRKP-YRKRARvDNMEPI-P-LMEGEGRSFRVLGFNQNQRAAFVQILMRFGV---GEYDWKEFASRMKQKSYEEIRD 1005
KRH52359      932 ITTARRP-YKKKARtDSTEPL-P-LMEGEGKAFRVLGFNQNQRAAFVQILMRFGV---GDFDWKEFTSRMKQKTYEEIKD 1005
EFJ18933      907 dAAKRTPgSRKKPRvEATGPP-P-LMEGEGKSILILGFNRKQRAMFVQVLMRFGF---GDFSWSEFASCFKHKTVDEIKE 981 
XP_002869306  862 PRTVTKP-YRKRNR-DKS-EL-P-VMEGGGKSFEVLGFNRTEREIFLRTFKRYGA---GNFDWKEFIHPLHMKTFDEINK 933 
EKC37026     1328 DSEKNKR-GSRQRGsEKDRPLpP-LLARVNGQIEVLGFNARQRKAFLNAVMRYGMppqDAFNSQWLVRDLRNKSEKVFKA 1405
XP_003245819 1380 GKKLKRK-PERKE--ERDRPLpP-LLARVGGNIEVLGFNARQRKAFLNAIMRYGMppqDAFNSQWLVRDLRGKSEKNFKA 1455
XP_015781829 1187 EEKTGRR-KGRNEKtEKDKPLpP-LLARVGGNIEVLGFNARQRKAFLNAIMRYGMppqDSFNSQWLVRDLRCKSERNFRA 1264
NP_001190884  815 PRTVTRP-YRKRAR-DNSEEI-P-LMEGEGRYLMVLGFNETERDIFLRTFKRYGA---GNFDWKEFVNPLYMKTYDEINK 887 

6RYR_W       1474 YVSLFMRHLCEPGADGAETF--------ADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPEL 1536
Q9S775        993 YGILFLKHIAEEIDENSPTF--------SDGVPKEGLRIEDVLVRIALLILVQEKVKFVEDHPGKPVFPSR 1055 thale cress
XP_002515445 1006 YGILFLSHIVEEI-TDSPNF--------SDGVPKEGLRIQDVLVRIAVLLLILEKVKFASEKPGIPLFTDD 1067
KRH52359     1006 YGTLFLSHIAEDI-TDSATF--------TDGVPKEGLRIQDVLVRIAVLLLIRDKVKFVSQHPQTPLFSDD 1067
EFJ18933      982 YAALFLMHVTEEQ-TDIPTF--------SDGIPKEGLRIQDVFVRLAILHLIWEKVKNLNENPSTSLFPSV 1043
XP_002869306  934 YGILFLQHIAENSKNNSSTFsvisamvsADGIPKEGIRSDELLMSMTFMMLLKEKCQFLDDHPTEPVFRDY 1004
EKC37026     1406 YVSLFMRHLCEPGADNAEAF--------ADGVPREGLSRQHVLTRIGIMSLVRKKVQEFEQINGLHSMPYi 1468
XP_003245819 1456 YVSLFMRHLCEPGADNSENF--------ADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEEINGFYSMPEL 1518
XP_015781829 1265 YVSLFMRHLCEPGADHLETF--------ADGVPREGMSRQHVLTRIGIMSLIRKKVQEFEHINGIQSMPip 1327
NP_001190884  888 YGILFLKHIAENPTDNSTNFkvitamvyADGVPKEGISSDELLVSMTFMMLVKEKCQFLDNHPTAPVFSNY 958
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