Conserved Protein Domain Family
GRAB

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pfam10375: GRAB (this model, PSSM-Id:431241 is obsolete and has been replaced by 431241)
GRAB domain
The GRAB (GRIP-related Arf-binding) domain is towards the C-terminus of Rud3 type proteins. This domain is related to the GRIP domain, but the conserved tyrosine residue found at position 4 in all GRIP domains is replaced by a leucine residue. The Arf small GTPase is localized to the cis-Golgi where it recruits proteins via their GRAB domain, as part of the transport of cargo from the endoplasmic reticulum to the plasma membrane.
Statistics
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PSSM-Id: 431241
Aligned: 23 rows
Threshold Bit Score: 78.0361
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
RVD80280      371 DPQDNVDRQLVTNLFISFLGLPRGDPKRFEVLQLIANYLKWTDEDRETA 419 
XP_002175621  352 ENAEKVDKQLISNLLVSFLSLPRADTKRFEILQLIASVLEWNDEQREQV 400 
ODV59613      413 NENSSVDKELISNLILKFLSIQRGDAKKFEVLKLISSYLNWDKNQQIQA 461 
SGZ52077      483 NTDNTVDRELISNVFLNFLQIPRGDSKKFEALLLISALLDWDEPRKVQA 531 
XP_004198418  391 NSNNTIDKDLVSNLILSFLQFPRGDTKKYEALQLISALLEWDESQKVSA 439 
EGV60116      135 SVDNTIDKELISNVLINFLQIPRGDTKKYEALQLLSSLLEWDESKRVAS 183 
ODV82844      323 STSELVDRELISNLFISFLQLPRFDSKKFEVLKLISNFLNWDDDKKQHA 371 
ONH68025      442 SDAETVDKELVTNLFISFLTIPRGDTKKFEVLQLISNYLNWDEDKKIQA 490 
ODQ63571      413 SDGGVVDKQIITNLFLSFLDIPRGDTKKFEVLQLISNFLGWDEEQKAQA 461 
GAO49033     1144 SSNSTVDRQLVTNLVLKFLSLPRGDARKFEALGVLGGFLGWTEEERGVA 1192
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