2YW2,2YS6,2XCL,2IP4,3LP8,1VKZ,1GSO,3MJF


Conserved Protein Domain Family
GARS_C

?
pfam02843: GARS_C 
Click on image for an interactive view with Cn3D
Phosphoribosylglycinamide synthetase, C domain
Phosphoribosylglycinamide synthetase catalyzes the second step in the de novo biosynthesis of purine. The reaction catalyzed by Phosphoribosylglycinamide synthetase is the ATP- dependent addition of 5-phosphoribosylamine to glycine to form 5'phosphoribosylglycinamide. This domain is related to the C-terminal domain of biotin carboxylase/carbamoyl phosphate synthetase (see pfam02787).
Statistics
?
PSSM-Id: 427016
Aligned: 960 rows
Threshold Bit Score: 44.0123
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2YW2_B           326 ALDVVLASRGYPEKPETGKIIhgLDYlksmEDVV----VFHAGtkkegnfT--------VTSGGRVLNVCAYGKTLKEAK 393 Aquifex aeo...
Q8U3N5           330 TVVKYIAPQGYPENPIKGVRI--EVNe--dKIREegarLIFAS-------Ide----nyTLLGSRALAVVGVSENLEEAE 394 Pyrococcus ...
Q5ZUW9           336 TVCKYAVPDGYPDNPLRHVEI--DIS-----AVEpkdtLYLAA-------Vnfkn-gklYATGSRTAAYVGIANTISEAE 400 Legionella ...
Q5NGF1           661 SVCKYLVPLGYPNQSVKNFEI--DIS-----QCPdnveLFLGA-------Vdykd-gklIGTGSRAIAVLGLGDTIAEAE 725 Francisella...
WP_014266800     336 SVCKYIVPDGYPDAPRKGDAV--SLP----SQLPaevtLFLSA-------Vdvkd-gelIATGSRTVAVVGRAATIAEAE 401 Granulicell...
O27494           331 TVCKYLVPEGYPESGVAGAEI--KVDe--kKIEDmgviTYYAA-------Vnqed-dhiYTSSSRALALVAPADDIYSAE 398 Methanother...
WP_023993152     331 TVCKYLVPNGYPDSGKAGQPI--SVDe--eKIKDegamVFYAA-------Vnqkd-gniLTTGSRALGLVSLADSIEEAE 398 Methanobact...
Q2NI86           332 SVCKYVVPDKYPNTHVADTVV--DVDe--dKINElgaqVFYAA-------VyqdmddsiKLTSSRALGVLAVKDSIKEAE 400 Methanospha...
NZAGRC:Abm4_0058 331 SVCKYIVPEGYPDTEYAGEKI--EVDe--kEIEDlgakVFYAS-------Vsedd-dgvKLTGSRALGIVAQGESISEAE 398 Methanobrev...
agres:mru_2113   352 SVCKYIVPDGYPDTPHAGELI--EIDe--eAIEAlgakVFYAA-------Vsqed-dgvHLSGSRALGIVAQGDTIAEAE 419 Methanobrev...
2YW2_B           394 ERAYEAIR--YvcfeGMHYRKDIGDK 417 Aquifex aeolicus
Q8U3N5           395 KIAQSAIRhvKg---PIFYRKDVGTR 417 Pyrococcus furiosus DSM 3638
Q5ZUW9           401 EIAEQQIKniKg---PLFHRKDIGTS 423 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Q5NGF1           726 QKAENAVKniYg---KLFHRPDIGTK 748 Francisella tularensis subsp. tularensis
WP_014266800     402 VLCEQVVQqiPg---PFFHRTDIGTA 424 Granulicella mallensis
O27494           399 ELCEEATAhvKg---RLYHRRDIGTR 421 Methanothermobacter thermautotrophicus str. Delta H
WP_023993152     399 KQCERATQyvQg---DLYHRSDVGTE 421 Methanobacterium sp. MB1
Q2NI86           401 KICEEAIKyvKg---EVYHRNDVATE 423 Methanosphaera stadtmanae DSM 3091
NZAGRC:Abm4_0058 399 KIAEKACEfvKg---PVYHRSDVGTE 421 Methanobrevibacter sp. AbM4
agres:mru_2113   420 KIAEEACGlvEg---NVYHRRDVGTE 442 Methanobrevibacter ruminantium M1
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap