Conserved Protein Domain Family
CH_AtKIN14-like
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cd21203: CH_AtKIN14-like 
calponin homology (CH) domain found in Arabidopsis thaliana Kinesin-like KIN-14 protein family
Kinesins are microtubule-dependent molecular motors that play important roles in intracellular transport and in cell division. This family includes a group of kinesin-like proteins belonging to KIN-14 protein family. They all contain a single copy of the CH domain at the N-terminus. CH domains are actin filament (F-actin) binding motifs.
Links
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Statistics
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PSSM-Id: 409052
Aligned: 13 rows
Threshold Bit Score: 132.924
Created: 7-Oct-2019
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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putative actin
Feature 1:putative actin binding site [polypeptide binding site]
Evidence:
  • Comment:Based on the structure evidence that Homo sapiens filamin-A binds F-actin.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         #   #                                                                     # ##  
O81635         46 RRYEAAGWLRDMIGvsngkdfpgepSEEEFRLGLRSGIVLCNVLNKVNPGSVskvveapddv---adgaalsafQYFENI 122  thale cress
F4IL57         46 RRYEAANWLRRMVGvvgakdlpaepTEEGLRLGLRSGIILCKVLNKVQPGAVskvvespcdailvadgaplsafQYFENV 125  thale cress
F4HZF0         56 RRYEAARWVRNTLGvvggrdlpadpSEEDFRIALRSGILLCNVLNRVKPGAVpkvveapndplvnqdgaalsafQYFENL 135  thale cress
XP_024400707  102 RRQHAISWLQGMVGslgl---ssdsTEEDLRLCLRNGINLCKLINKVQPGAVqkvvvnavls--nhpdgaqsafQYFENV 176  Physcomitrell...
EFJ19920       10 RRYLAALWMEEVVGplhl---svepSEEEFGRCLRNGISLCKLVNSVQPGSVsrvvescsss---padgalsayQYFENV 83   Selaginella m...
F4JX00         42 GHQSLVEWLNETLPylnl---pweaSEEELRACLVDGTVLCNLLNQLSPGSMrmgg---------------sfePGCVNI 103  thale cress
AMS24249       25 RRYQAATWLQRTVGpldl---pidpSEEDMRLCLRDGTVLSRLLNKLDPTLIskvlevd---------dlshdsISQDSL 92   Marsilea vestita
KMZ74520       16 RRLEFVEWINNLLEldlp----ldiSEPYLCEIFLDGTVLRGILKKLHIDVTeecld------------dygfrRNMENV 79   Zostera marina
GAX84289       49 RRKEAAAWLQQVTAssv-----asdTDNDFRSTLADGVILCKIANILCPDAIkiqass----------alsshqSRYENV 113  Chlamydomonas...
RMZ52520       78 KRRAASEWIGMALGvsv-----pheTDQAFRRALADGVTLCRLVNWLRPGSIpkvveampdgsgtpshatgdviQTFENV 152  Auxenochlorel...
GBF90289       14 KREAAAEYIQLVTGvav-----phgSDRELRAALADGVLLCEAVNTAFPRAVpqvltqldv----epgpagleeQRRRNV 84   Raphidocelis ...
PNW83261       63 RRKAAAEFIKDCTSedi-----pysNDLHFRQSLCDGRLLCKVLNTVYANAVpkve--------------ggdaAEDANV 123  Chlamydomonas...
GAQ78746       40 RREQAVAFINHLSGaglp----sdvSEGQFQESLSDGVLLLQMLNKILAESHqetvkvvqfds-dsnqeahaafQSMENI 114  Klebsormidium...

Feature 1         ## #         #########         # ## ##  ##  #
O81635        123 RNFLVAIEEM---GLPSFEASDMEk----gGKSIRIVNCILALKS 160  thale cress
F4IL57        126 RNFLVAIQEM---GFPTFEASDLEq----gGNASRVVNCVLAIKS 163  thale cress
F4HZF0        136 RNFLVFVEEM---GIPTFEVSDFEk----gGKSARIVECVLALKS 173  thale cress
XP_024400707  177 RNFLVAIEEM---GLPSFEVSDLEqgsmssSSSAKLVDCILALKS 218  Physcomitrella patens
EFJ19920       84 RNFLVAMEDL---SIPTFDASDLEeasfggGSVARVVDCILGLKL 125  Selaginella moellendorffii
F4JX00        104 ERFLAAMDEM---TLPRFEVSDLEq-----GDMIRVIQSLKALKA 140  thale cress
AMS24249       93 KGFLKAVTLL---KIPAFERLDLEqpnyrpSSIEKVVDCLLSLRS 134  Marsilea vestita
KMZ74520       80 ERCILSIDEA---GFPIFDASDLEr-----GSTFSMIDCLLCLRD 116  Zostera marina
GAX84289      114 QSFIRVMQSLdvpSDSTFSFEDLTss--eeAERPRVADCVLWLKR 156  Chlamydomonas eustigma
RMZ52520      153 TNFIRVARDL---TGETFSARDLEeg---gEERPGVAGCILGLRD 191  Auxenochlorella protothecoides
GBF90289       85 AACLAAIARVl-pPGCGFSPADLEce--aeTERCRVVDTILLLRA 126  Raphidocelis subcapitata
PNW83261      124 GAFLHFMEKTnvpSDARFSVQDLRsd--gwDDRPRVTECLLWLQK 166  Chlamydomonas reinhardtii
GAQ78746      115 SNFLRRVKAMn-pELKLFEASDFEkkgygpSRTARIVDSILDLEL 158  Klebsormidium nitens

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