pfam11779: SPT_ssu-like (this model, PSSM-Id:403091 is obsolete and has been replaced by 463347)
Small subunit of serine palmitoyltransferase-like
Serine palmitoyltransferase (SPT) catalyzes the first committed step in sphingolipid biosynthesis. In mammals, two small subunits of serine palmitoyltransferase, ssSPTa and ssSPTb, substantially enhance the activity of SPT, conferring full enzyme activity upon it. The 2 ssSPT isoforms share a conserved hydrophobic central domain, which is predicted to reside in the membrane.