3CZN,5JM0


Conserved Protein Domain Family
Glyco_hydro_38

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pfam01074: Glyco_hydro_38 (this model, PSSM-Id:395852 is obsolete and has been replaced by 426030)
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Glycosyl hydrolases family 38 N-terminal domain
Glycosyl hydrolases are key enzymes of carbohydrate metabolism.
Statistics
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PSSM-Id: 395852
Aligned: 44 rows
Threshold Bit Score: 226.358
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3CZN_A         82 KVFVVPHSHNDPGWIQTFEEYy---------QHDTKHI--LSNA---LRHLHDNpEMKFIWAEISYFARFYHDLGENKKL 147  fruit fly
Q8A5X3        297 TVYLVQHTHTDIGYTKPQTEIls------ehLRYIDYAieYCEQ---TKDYTNDaKFRWTCESAWAVDEYLKNRPEEQVN 367  Bacteroides t...
Q8IPB7         48 NVHLVAHTHDDVGWLKTVDQYyygse-tkiqKAGVQYI--IDSV---VEALLRDpEKRFIYVESAFFFKWWKEQKPKVQE 121  fruit fly
O00754         64 NVHLLPHTHDDVGWLKTVDQYfygik-ndiqHAGVQYI--LDSV---ISALLADpTRRFIYVEIAFFSRWWHQQTNATQE 137  human
Q20829         37 TAHLIPHTHDDLGWIKTVDQYfwgak-pelvPVGVQYI--YNTV---IDELLKNpDRRFSFAETGFLWRWYTSNSDFDRH 110  Caenorhabditi...
Q9FKW9         48 NVHLVPHSHDDVGWLKTVDQYyvgsn-nriqNACVRNV--LDSV---VDSLLRDpNRKFVFAEMAFFTRWWEEQSPERQE 121  thale cress
P94078         39 NVHLVPHSHDDVGWLKTVDQYyvgsn-nsirGACVQNV--LDSV---IASLLDDeNRKFIYVEMAFFQRWWRQQSNAKKV 112  thale cress
Q8LPJ3         38 NVHVVPHSHDDVGWLKTVDQYyvgsn-nsiqVACVQNV--LDSI---VPALLADkNRKFIYVEQAFFQRWWNEQSEEIKR 111  thale cress
P34098         43 NVHIVAHTHDDVGWLKTVDEYyygsn-msiaFAGVQYT--LDTA---ITCLLANpERKFIYVEIAFFQRWWDEQSTTMQN 116  Dictyostelium...
WP_012392899   98 TMFMVSHFHYDPVWWNTQGAYtsqwhedppgRARQTNG--FELVhahLEMARRDpDYKFVLAEVDYLKPYWDTHPQDRAD 175  Mycobacterium...
3CZN_A        148 QmKSIVKNGQLEFvTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMN--VTPTASWAIAPFGHSPTMPYILQ-KSGFKNM 224  fruit fly
Q8A5X3        368 KlKKYIAEGQIEVa---SMYFNMSEIVDENSFKTFLQPVKEFRKHGI---PSALAMQNDVNGIAWCLADYLP-DLGIKYL 440  Bacteroides t...
Q8IPB7        122 AvKMLVEQGRLEFiGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGecGRPRVGWQIDPFGHSREMASMFA-QMGFDGM 200  fruit fly
O00754        138 VvRDLVRQGRLEFaNGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGndGRPRVAWHIDPFGHSREQASLFA-QMGFDGF 216  human
Q20829        111 QlQKLVKNGQIEIiGGGWVQNDEATSHYVDIIDQMTLGLQRLEQIFGecGKPVTGWQIDPFGHSREMANIYR-EMGYSSV 189  Caenorhabditi...
Q9FKW9        122 QvRRLVKSGQLEFvNGGWAMNDEATCHYIDMIDQTTKGHRFIKQQFNt--tPRAAWQIDPFGHSSVQAYLLGaELGLDSV 199  thale cress
P94078        113 KvKKLVDSGQLEFiNGGMCMHDEATPHYIDMIDQTTLGHQFIKTEFGq--vPRVGWQIDPFGHSAVQAYLLGaEFGFDSL 190  thale cress
Q8LPJ3        112 IvKELIHSGQLELiNGGMCMHDEAAPHYIDMIDQTTLGHRFIIREFNv--tPRIGWQIDPFGHSAVQAYLLGaEVGFDSV 189  thale cress
P34098        117 IvKGLVESGQLEFiNGGYCMNDEATTYYDDTIDQMTLGHQFLWENFG--VMPKIGWHIDPFGHSATQARIFG-QLGFDAF 193  Dictyostelium...
WP_012392899  176 L-RRFLAQGRVEVmGGTYNEPNTNLTSPETTIRNLVHGIGFQRDVLG--ADPATAWQLDVFGHDPQFPGMAA-DAGLTSS 251  Mycobacterium...
3CZN_A        225 LIQRTHYSVKKELaq---------qRQLEFLWRQIWDnkgd-talfTHMMPFYSYdiphtcgpdPKVCCQFdfkrmgsfg 294  fruit fly
Q8A5X3        441 WMGEHHYKSQVPFn-----------MPTVFQWESPSGkp-----ilTYRADH-------------YNTGNFwgieq---- 487  Bacteroides t...
Q8IPB7        201 FFGRLDYQDKDERlm---------tKNAEMIWHGSANlgee-adlfSGALYNNYQa--------P-DGFCFdilcndapi 261  fruit fly
O00754        217 FFGRLDYQDKWVRmq---------kLEMEQVWRASTSlkpptadlfTGVLPNGYN---------PPRNLCWdvlcvdqpl 278  human
Q20829        190 YFARIHYLEKQIRlk---------nKTLEFMWNTSDDitdn--klfTGAFFNDNYg-------pP-EGFCWdslcgddpi 250  Caenorhabditi...
Q9FKW9        200 HFARIDYQDREKRka---------eKSLEVIWRGSKTldss-sqifTNIFFVHYGp--------P-TGFHYevtddyvpl 260  thale cress
P94078        191 FFARIDYQDRAKRlr---------eKTLEVIWQGSKSlgss-sqifTGVFPRHYDp--------P-EGFTFeindvsapi 251  thale cress
Q8LPJ3        190 FFGRIDYQDREKRyk---------eKTLEVIWRGSKSlgss-sqifAGAFPTNYEp-------pP-GGFYYeitddspvv 251  thale cress
P34098        194 IIGRMDYQDIEARle---------nKQMEFMWRSTQStpen--qvfTSVLRAMYC---------TPDGFNFeqgddpiqd 253  Dictyostelium...
WP_012392899  252 SWARGPHHQWGPAqggrgegvermqFCSEFEWISPSGrg-----llTHYMPAHYSagwwmdsssS-----La-------- 313  Mycobacterium...
3CZN_A        295 lscpwkvpprtisdqnvaaRSDLLVDQWKKKAELYRtnVLLIPLGDDfrfkqntewDVQRVNYERLFEHIN-SQA-HF-N 371  fruit fly
Q8A5X3        488 --------------gdiqkTEPKLLHYLSELERKHYpfDAVGVQYSGy-------fTDNSPPSIIECKLIReWNE-KYaY 545  Bacteroides t...
Q8IPB7        262 id------gkhspdnnvkeRVDAFLAYVTEMAEHFRtpNVILTMGEDfhy---qnaDMWYKNLDKLIKYGNeRQA-NGsN 331  fruit fly
O00754        279 ve------dprspeynakeLVDYFLNVATAQGRYYRtnHTVMTMGSDfqy---enaNMWFKNLDKLIRLVNaQQA-KGsS 348  human
Q20829        251 md------nlniegynvkeKVDAFVDHVKNQAAHQStnQVMLLMGSDfqy---tnaNSWYVNLDKLIKYVNaDTS-K--K 318  Caenorhabditi...
Q9FKW9        261 qd------nprfdgynikeAVNDFVNASLVYANVSRgnHVMWTMGDDfqy---qfaESWFRQMDRLIHYVN-KDG----R 326  thale cress
P94078        252 qd------dpllfdynvqeRVNDFVAAALAQVNVTRtnHIMWLMGTDfry---qyaYSWFRQIDKFIHYVN-KDG----R 317  thale cress
Q8LPJ3        252 qd------dpdlfdynvqeRVNAFVAAALDQANITRinHIMFTMGTDfry---qyaHTWYRQMDKLIHYVN-LDG----R 317  thale cress
P34098        254 d--------pnlfdnnvdsRAEQFTQVALEYATHYRtnNVLIPFGCDfay---lnaQMYYKNIDKLIAHIN-SNP-DKyG 320  Dictyostelium...
WP_012392899  314 ------------------eAAAATYALFDELKRVALtrNVLLPVGTD------------YTPPNKWVSEIHrDWAaRYtW 363  Mycobacterium...
3CZN_A        372 VQAQFGTLQEYFDAVHQaeragqae-fptlsgdFFTYA 408  fruit fly
Q8A5X3        546 PKLRSATASEFMDYVTEryg-----------dkIPAYR 572  Bacteroides thetaiotaomicron
Q8IPB7        332 INLLYSTPSCYLKSLHDagitwp-----tksddFFPYA 364  fruit fly
O00754        349 VHVLYSTPACYLWELNKanltws-----vkhddFFPYA 381  human
Q20829        319 VRVIYSTPACYTKAVQAktptls-----vkhddFFPYA 351  Caenorhabditis elegans
Q9FKW9        327 VNALYSTPSLYVDAKNVanvtwp-----lkthdFFPYA 359  thale cress
P94078        318 LNVLYSTPSIYTDAKYAaneswp-----lktddFFPYA 350  thale cress
Q8LPJ3        318 VNAFYSTPSIYTDAKHAaneawp-----lktedYFPYA 350  thale cress
P34098        321 LNLLYSTPSIYIDAVNDanlvwe-----vktddLFPYA 353  Dictyostelium discoideum
WP_012392899  364 PRFVCGLPREFFAAVRAeladrgavaspqtrdmNPIYt 401  Mycobacterium marinum
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