Conserved Protein Domain Family
Collectrin
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pfam16959: Collectrin (this model, PSSM-Id:374904 is obsolete and has been replaced by 465322)
Renal amino acid transporter
Collectrin is a single-pass transmembrane protein that is homologous to the C-terminal region of human angiotensin-converting enzyme 2, ACE2, found in Peptidase_M2 pfam01401. Collectrin is critical for normal amino acid reabsorption in the kidney.
Links
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Statistics
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PSSM-Id: 374904
Aligned: 42 rows
Threshold Bit Score: 190.902
Created: 25-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_002719891  617 SIKVRISLKTALGDQAYEWNDSEMY-LFRSSVAYAMRKYFSEVKNQTILFGEEDVRVSDLKPRISFNFFVTAPNNVNDII 695 rabbit
XP_001515621   63 AFKVRFSIKTALGDNAYAWDSNEEY-LFKAMVAFSMRKYPNRGK-----TEVSNVLLCNITERVSFWFVVTDPSNN-QTI 135 platypus
XP_001489993   24 AFKVRLSIRTALGDKAYAWDTNEEY-LFKAMVAFSMRKVANREK-----TEISHVLLCNVTQRVSFWFVVTDPSEK-HTL 96  horse
6_pfamImport    1 AFKVRLSIRTALGDKAVSGEPAKEYrINKVVFLWSVKISPNRRT-----RKISHVLLCNITQRVSFWFVVTDPTKN-YTL 74 
XP_005037421   27 AFKVRISIKTALGDNAYAWDANEEY-LFKAMVAFAMRRYSSKST-----TQISNVLLCNVTDRVSFWFVVTDSSKNVTTV 100 collared flyca...
XP_003218941   27 AFKVRLSIKTALGDNAYSWDATEEY-LFKAVVAFAMRRSFSQEA-----TQVSNVLLCNVTERVSFWFVVTDSSTNKTTV 100 green anole
ETE61881       35 AFKVRLSIKTALKENAYSWDATEEY-LFKAVLAYAMRRYLIQET-----TQISNVLLCNVTSRVSFWFVVTNSFTNITTI 108 king cobra
21_pfamImport   1 AFKVRLSIRTALGDKAYAWDTNEEY-LFKAMVAFSMRKVPNRETTEVSHFCLF-------FQRNSTWVVRGSPPTPH--- 69 
XP_005997909   27 AYKVRLSIKTALGDKAYNWNENEQY-LFRATIAFAMRQYLKNE-----IFRASNVLTCNETQRVSFWFVVTSPENPSVTI 100 coelacanth
XP_007500934   27 AFKVRLSLKTALGDKAYTWNENEEY-LFKAMVAFSIRTFSSREK-----IEISNVLLCNVTKRVSFWFVVTDPSEN-QTV 99  gray short-tai...

XP_002719891  696 PRNEVEEAI--SMSRSRINDIFRLDDNS--LEFVGIQPTLEPPYESPVPIWLVVFGVVMGMIVIGIVVLIFTGIKDRRK 770 rabbit
XP_001515621  136 PAGEVQAAI--RMNRNRINNAFFLNDQT--LEFLKIPSTLAPPTEPSVPVWMIVFGVVFCLVIIGIALLIMSGIQQHRR 210 platypus
XP_001489993   97 PAVEVQEAI--RMNRNRINNAFFLNDQT--LEFLKIPSTLIPPTDPPVPIWIIIFGVIFCIVIVAIILLILSGIRQRRR 171 horse
6_pfamImport   75 PADEIQSAI--RMNRNRINSAFSLNDQT--LEFLKIPSTLAPPTDPSVPIWIIIFGVVFCIVIVAITLLVLSGIRQRRR 149
XP_005037421  101 PGSEVEAAI--RMNRNRINNAFLLSDKT--LQFLKITSTLSPPVEPSTPVWLIVFGVVLCLIVAGIVFLIISGIRKHKK 175 collared flycat...
XP_003218941  101 PKSVVEAAI--RLNRNRINSAFLLDDST--LQFLQISATLAPRVEPPVPTWLIVFGVSFCLVAVGIVLLIISGIHKNRR 175 green anole
ETE61881      109 PRNDVEAAI--RMNRNRINNAFLLTDDT--LQFLGISSTLAPPAEQLLPIWLIVFGVILCIIVIGIVLVVSFGIYHRKR 183 king cobra
21_pfamImport  70 PQLLNEAGLhpRDLEEDVNHPRHLSSSTtpLDFLYI-PGLQHSTDGSEPHWLISYPVMDCCNVVITLILIVFAI----- 142
XP_005997909  101 PENDVAEAI--RLNRHRINNAFLLSDKT--LQFIGIPPTLSPPVESSLPVWLILFGVVLGLVVIGIIFMIVTGIRQRKR 175 coelacanth
XP_007500934  100 PAGEVQGAI--RMNRNRINNAFILNDQT--LEFLEIPATLGPPTEPSTPIWVIIFSVVFCLVIVGIVLLIVSGIRQRRR 174 gray short-tail...
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