pfam15353: HECA (this model, PSSM-Id:373778 is obsolete and has been replaced by 464667)
Headcase protein family homolog
HECA was characterized first in Drosophila where it regulates the proliferation and differentiation of cells during adult morphogenesis. In humans, HECA affects cell cycle progression and proliferation in head and neck cancer cells. It by slows down cell division of oral squamous cell carcinoma cells and may thereby act as a tumor-suppressor in head and neck cancers.