pfam14500: MMS19_N (this model, PSSM-Id:373098 is obsolete and has been replaced by 433995)
Dos2-interacting transcription regulator of RNA-Pol-II
This domain, along with the C-terminal part, pfam12460, is an essential component of a silencing complex in fission yeast that contains Dos2, Rik1, Mms19 and Cdc20 (the catalytic subunit of DNA polymerase-epsilon). This complex regulates RNA polymerase II (RNA Pol II) activity in heterochromatin and is required for DNA replication and heterochromatin assembly.