Conserved Protein Domain Family
Involucrin2

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pfam06994: Involucrin2 (this model, PSSM-Id:369164 is obsolete and has been replaced by 429235)
Involucrin
This family represents a conserved region approximately 60 residues long, multiple copies of which are found within eukaryotic involucrin, and which is rich in glutamine and glutamic acid residues. Involucrin forms part of the insoluble cornified cell envelope (a specialized protective barrier) of stratified squamous epithelia. Members of this family seem to be restricted to mammals.
Statistics
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PSSM-Id: 369164
Aligned: 18 rows
Threshold Bit Score: 29.3741
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGW13874     189 PEEQELIPGEKQ-----------QKLQK----QELH--QEQrhQEPQKPELQLAQ 226 Chinese hamster
XP_005203893 109 SQVQEVHVEQQQ-----------QESQV----QEQHveQQQ--QESQVQEQHVEQ 146 cattle
P48997       154 TQEQGLCLGQKQq----------QQQQDmlvpQELHlrQHQ--EKLQDPELHLGQ 196 house mouse
EHB13102      60 PQEEELYLRQQQh---------pQKPPE----PELHlgKQQ---EPQEPE-QPPE 97  naked mole-rat
P48997       311 LHKPELYLRKQQy---------qE-SPD----PELSlgKQQh-QECQEPELQLEE 350 house mouse
XP_006232869 156 lAPQELHMGQHQk----------EKLQE----PELPlgQQQ--KTPEEQELILGE 194 Norway rat
XP_003803978 176 SQEQGLCLIKQRe---------pQESQE----QRLHlgKEQ---ESQEQRLHLGK 214 small-eared galago
XP_008262643 119 PQVQEVHVGQQQpqvqevhvgqqPEPQV----QEVHvgQQP---EPQVQEVHVGQ 166 rabbit
NP_999613    258 SQEQELHVDQHQq---------qQESQE----QELHvdQQQ--QELQVQEV---Q 294 pig
NP_999613     83 PQQQELHVEQQQq---------qQESQV----QELHvdQQQqqQESQEQELHVDQ 124 pig
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