Conserved Protein Domain Family
GT4_UGDG-like

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cd03817: GT4_UGDG-like 
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins
This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Statistics
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PSSM-Id: 340844
Aligned: 28 rows
Threshold Bit Score: 348.5
Created: 15-Dec-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                       #                                                                
AAK38877       2 RIGIFSEa-YLPLISGVVTSVVNLKEGLealGHEVYVITPIPSKdkfe-----ndpSVIripgwv------iprksLKGF 69  Acholeplasma la...
ABI95889       2 VIVLVVDs-FENKSNGTSMTAARFCKALrehGHSVRVVAPFVQGegfy-----alkERYiplv---------tklaHKQH 66  Helicobacter felis
AAP77273       2 IIAIVVDs-YKDRSNGTSMTAFRFARALierGHCVRIITTNPTQeesn-----eqsSGEefyfvkeryipivteisHKQH 75  Helicobacter he...
NP_207219      2 VIVLVVDs-FKDTSNGTSMTAFRFFEALkkrGHVMRVVAPHVDNlgse-----eegYYNlkeryip----lvteisHKQH 71  Helicobacter py...
CAI49700       3 TVAAFTDt-YLPTVNGVSYTASTWRDRWcrrGGRMPLVYPAADGyqpe-----dgeHPVgsv------------rfPWYE 64  Natronomonas ph...
AAV46283       5 HVATFTDt-YLPTVNGVTYTVETWRDRWrdrGGRMDVVYPKSDHdsse-----neyPVRs---------------lPFPF 63  Haloarcula mari...
NP_213400      2 KIALFTDs-FRKDLGGGTQVARQLAFGLskkGYEVLVITGSTAEeetp-----fkvLKLpsik---------ypfyHNVE 66  Aquifex aeolicu...
YP_095659      8 KILTVLDs-YPPDLNGGAYFTHRLAKFLqakGHEVLVICPSRSLkqgy-----tsyEGVnlygvrsw--palgyknFRVC 79  Legionella pneu...
CAN91185      64 KVAILSDftRIPYANGAVFQTRALYRALntcGHQATLIGPRDPDasad-----eipPGTvalpsl------plrtyPGVH 132 Sorangium cellu...
YP_003767759 281 RILIGADt-FPPNVNGASFFAERLARGLarrGHDVHVACPSADGpsrteerdgytvHRIrsrai-------pfhgnYRFC 352 Amycolatopsis m...
Feature 1                                                                                        
AAK38877      70 RLVLFVKRYVrkMRKLKLDVVHIHTE--FSMGKLGLAVAKkERIPSVYTLHTSYQ--DYTHYVSKLLTrfapnaakkl-- 143 Acholeplasma la...
ABI95889      67 ILFGKPHEKTlrQAFEGADIVHLFLP--FKLEKVALKVARaMKIPFVGAFHLQPE--HITYNMRLQNLgwlnrllf---- 138 Helicobacter felis
AAP77273      76 MIFGSPDSHIleSALKGCDIAHFYLP--FALEIAGVHLCRkMKIPYISAFHLQPQ--HISYNMNMNFKwfnaylfr---- 147 Helicobacter he...
NP_207219     72 ILFAKPDEKIlrKAFKGADMIHTYLP--FLLEKTAVKIAReMQVPYIGSFHLQPE--HISYNMKLGWFswfnmmlf---- 143 Helicobacter py...
CAI49700      65 GFRLGRPAVPdaVERAAPDVVHAHTP--FALGLAAARLAArSDAPLIVSYHTPVS--EYAGYVSDAFAdavgvaa----- 135 Natronomonas ph...
AAV46283      64 YEGFRLGMPQipKGVRDAELVHAHTP--FSLGMAGQRLAGkLDIPFVASYHTPTS--EYAEYVSFNGAvesavrssa--- 136 Haloarcula mari...
NP_213400     67 IALPNVELLKe-LKNFNPDVIHYHDP--FLAGTMALLMGKiLKIPTVGTIHIHPK--QLTYHGIKIDNgviakk------ 135 Aquifex aeolicu...
YP_095659     80 WPFFIKKGILkaITDFNPDVVHLQGK--FFLGGICYRACRkKGIPLMATNHFMPE--NFFHYTHLPKYfekwfhrtt--- 152 Legionella pneu...
CAN91185     133 LPIPVGSSVLd-PMRWDFDICFAQTTtlLVEFGIWLRKMRgIPLLCVNTTHLAAAydVLLPERVSRIGavhtvlhktlra 211 Sorangium cellu...
YP_003767759 353 TPGGARTEAGplLDRLRPDVVHVQAH--FGVGRALLEAAAeRGLPGMATNHFMPD--NLLGYTPFPKRvknaiarwa--- 425 Amycolatopsis m...
Feature 1                                                                                       #
AAK38877     144 -agkinnqytKNCHMTIVPTkk--iyDKMIRLKHDge-fTIIPSGINLKPFykssytseqvqalkdklgirnDEFVAILV 219 Acholeplasma la...
ABI95889     139 --wwfkqsyyQHFTHIHCPSpf--ikSELIKHNYGgk-kYAISNGFDPMYAprphn------------tksdDLYHIAMV 201 Helicobacter felis
AAP77273     148 ---rfykafyRYTHHIHCPSqlmeeeIQKAGYGGKk---FVISNGFQINRAqscvk------------pfddTFFHIISV 209 Helicobacter he...
NP_207219    144 --swfksshyRYIHHIHCPSkf--ivEELEKYNYGgk-kYAISNGFDPMFRfehpqk----------slfdtTPFKIAMV 208 Helicobacter py...
CAI49700     136 ----dryerwFLNRADAVVAps--qtAAERIDAEEtp-vYVVSNGVDTDRFrpvgehavt---afrdryglpDGPLVGYT 205 Natronomonas ph...
AAV46283     137 --esyerwflGRADTVIAPSer--aaTHLRESIGLdttvTVVPNGVDTTAFepvdttaf------rerydlpDGPIVGYT 206 Haloarcula mari...
NP_213400    136 ----lvsffgNFTDCVVFVSky---qKKLYEELDSfc-vKVIYNGIPDYFFvsekr------------klrnPRNRILTV 195 Aquifex aeolicu...
YP_095659    153 --wnividmlNHVKIVTTPTht--aaNLLKEVHIQke-iHVVSCGVDLQKFqpkqnanl-----irqrykipDKPILLYA 222 Legionella pneu...
CAN91185     212 pmerlfvdlyNQGDGLVVLSeg--lrDYWRERGVTvp-iHVIPRMVPEDVFerplgpdpyv-qlleergldpRGPRLVCA 287 Sorangium cellu...
YP_003767759 426 --wrdllrvyRDARIVTTPTpr--aaEVLAGIGLDrp-vQVVSCGIDLAHYaapai------------rpddRPMSVLFV 488 Amycolatopsis m...
Feature 1        ##                                                             #                
AAK38877     220 ARIAKEKSIGDLVEAFVEFyks-ypnSRFIIIGDGPDKPVLdklidskkaSKYINTLGFVKNAEVGLYYQiADVFLNAST 298 Acholeplasma la...
ABI95889     202 GRYSPEKNQRVLIEAAHLSkha--akIQLHLKGQGPQLASLqkh---askLAHRVDFGFLEPDELVKLLYqCDLYVHTAD 276 Helicobacter felis
AAP77273     210 GRFSKEKRQDILIKAITQSkya--nnIKLHLHGIGPKEQYLrklc--dklLINPPEFGFIDNNILIEKLKcCHLYVHSAE 285 Helicobacter he...
NP_207219    209 GRYSNEKNQSVLIKAVALSkyk--qdIVLLLKGKGPDEKKIkll---aqkLGVKAEFGFVNSNELLEILKtCTLYVHAAN 283 Helicobacter py...
CAI49700     206 GRHGREKRLGDVLAATAGLd------AGVVIAGAGPATPELrrr---taaREDVRLLGFLERNELPAFYTaLDAFAFPSP 276 Natronomonas ph...
AAV46283     207 GRHGYEKCLEDIVTACEGLd------VTVVFAGDGPARESLeata--ehsDADVRFLGFLDRVELPELYStLDVFAFPSP 278 Haloarcula mari...
NP_213400    196 SRLDKDKNPEFALKCVAEIske--vpVEYTIVGEGNEKEKLekla--rklGIKANFLGFVPREELPELYLsHDVLLNTSK 271 Aquifex aeolicu...
YP_095659    223 GRLDKEKNLSIAIKAFYKArqs--idAHFVLTGRGAELQRLkklvqtlnlTEHVTFTGYLSDAEYPLVYSlANCFVNPGT 300 Legionella pneu...
CAN91185     288 GRHTREKSQHRLIRIFAEHiaphepqATLTLVGDGPDSAAYaalarelgvARRVIFTGEVPYSQISDYYRhANLFLHASL 367 Sorangium cellu...
YP_003767759 489 GRLDAEKNIDQLLRALVPLp-----hVRADLVGDGTRRHELetlateldiTDRVTFHGFVPDAELVHRYAeADVFCMPGT 563 Amycolatopsis m...
Feature 1              #                                                                         
AAK38877     299 TETQGLTYVEALAA-SLPIIVRYDDVFDAFVEdgkNGIFFNkne----------elvKHLIHIRQNPeil-------gtL 360 Acholeplasma la...
ABI95889     277 VEGEAIACLEAMACgIVPIISDSKISATNQFAl-dDRSLFKsndprd----ladkidWWLDHPEERLqae-------drY 344 Helicobacter felis
AAP77273     286 VESEAISCLEAVSIgLVPVIADSKISATTQFAl-dERSLFKtnniadls-akidywvEHSKEREQMKe----------qY 353 Helicobacter he...
NP_207219    284 VESEAIACLEAISVgIVPVIANSPLSATRQFAl-dERSLFEpnnakdlsakidwwleNKLERERMQNe-----------Y 351 Helicobacter py...
CAI49700     277 VETQGLVALEAIAC-GTPVVAADGGALPETVDsgeTGCHFPvgd-----------vrAFRTALRQTLart-------dvL 337 Natronomonas ph...
AAV46283     279 VETQGLVALEANCC-GTPVAGVDAGALSDTIEdgeTGYTYDegdidgfr-raiervlDEQEHLRERC------------L 344 Haloarcula mari...
NP_213400    272 TETFGLSFAEAMAT-GMPVIALKEGSAPEIVGd--GGILCEekve---------cvkKAFLKLYQNPely-------fkL 332 Aquifex aeolicu...
YP_095659    301 AELQSIVALEAIAS-GLPLLAAKAMALPELVKegvNGYLFDpndv--------etlsCYMVKILSDRtfseqmgresrkL 371 Legionella pneu...
CAN91185     368 SETFGNVLSEALWCgSPTVAFADGMGVSSQIQsghNGLLIDpgrg---------piaEESANAAFGKavla----ltrdP 434 Sorangium cellu...
YP_003767759 564 AELQSLATMEAMAA-GLPVIAADALALPHLVHhatNGYLFEpgai--------ttisRWIADLAADPear-------akM 627 Amycolatopsis m...
Feature 1                                      
AAK38877     361 SKNAEISTKPyake---vyaKSCETLYLDL 387 Acholeplasma laidlawii
ABI95889     345 VQNATRYTLDka-------iEQALAMYQEV 367 Helicobacter felis
AAP77273     354 AKSASKYALE----------KSIDKIINMY 373 Helicobacter hepaticus ATCC 51449
NP_207219    352 AKSALNYTLEns-------vIQIEKVYEEA 374 Helicobacter pylori 26695
CAI49700     338 SDRCVARREQla------veRAIDRLGDVY 361 Natronomonas pharaonis DSM 2160
AAV46283     345 ARRDIISVEHa--------iDKLADVYDSV 366 Haloarcula marismortui ATCC 43049
NP_213400    333 SQKAPERAHVfrce---rflKDYESLYEEV 359 Aquifex aeolicus VF5
YP_095659    372 SQEHDIKRTI----------EQYETLYQSM 391 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
CAN91185     435 LAAARLGSAAaqrarersspLVVQRMLANA 464 Sorangium cellulosum 'So ce 56'
YP_003767759 628 GAASKAIVARhd------idEALATFEAQY 651 Amycolatopsis mediterranei

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