Conserved Protein Domain Family
HAD_like

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cl21460: HAD_like Superfamily 
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Haloacid Dehalogenase-like Hydrolases
The haloacid dehalogenase (HAD) superfamily includes carbon and phosphorus hydrolases such as 2-haloalkonoate dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, among others. These proteins catalyze nucleophilic substitution reactions at phosphorus or carbon centers, using a conserved Asp carboxylate in covalent catalysis. All members possess a conserve alpha/beta core domain, and many also possess a small cap domain, with varying folds and functions.
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Taxonomy: root
PubMed: 573 links
Book:
Protein: Related Protein
Related Structure
Statistics
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Accession: cl21460
PSSM Id: 328728
Name: HAD_like
Created: 5-Sep-2014
Updated: 5-Dec-2016
Superfamily
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Curated CD Hierarchy
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cd01427:HAD_likecd01431:P-type_ATPasescd01624:HAD_VSP_likecd01625:HAD_PNPcd01627:HAD_TPPcd01629:HAD_EPcd01630:HAD_KDO-likecd02073:P-type_ATPase_APLT_Dnf-likecd02076:P-type_ATPase_Hcd02077:P-type_ATPase_Mgcd02078:P-type_ATPase_Kcd02079:P-type_ATPase_HMcd02080:P-type_ATPase_cationcd02081:P-type_ATPase_Ca_PMCA-likecd02082:P-type_ATPase_cationcd02083:P-type_ATPase_SERCAcd02085:P-type_ATPase_SPCAcd02086:P-type_ATPase_Na_ENAcd02089:P-type_ATPase_Ca_prokcd02092:P-type_ATPase_FixI-likecd02094:P-type_ATPase_Cu-likecd02585:HAD_PMMcd02586:HAD_PHNcd02587:HAD_5-3dNTcd02588:HAD_L2-DEXcd02598:HAD_BPGMcd02601:HAD_Eyacd02603:HAD_sEH-N_likecd02604:HAD_5NTcd02605:HAD_SPPcd02607:HAD_ThrH_likecd02608:P-type_ATPase_Na-K_likecd02609:P-type_ATPasecd02612:HAD_PGPPasecd02616:HAD_PPasecd04302:HAD_5NTcd04303:HAD_PGPasecd04305:HAD_Neu5Ac-Pase_likecd04309:HAD_PSP_eucd07499:HAD_CBAPcd07500:HAD_PSPcd07501:HAD_MDP-1_likecd07502:HAD_PNKP-Ccd07503:HAD_HisB-Ncd07504:HAD_5NTcd07505:HAD_BPGM-likecd07506:HAD_likecd07507:HAD_Pasecd07508:HAD_Pase_UmpH-likecd07509:HAD_PPasecd07510:HAD_Pase_UmpH-likecd07511:HAD_likecd07512:HAD_PGPasecd07514:HAD_Pasecd07515:HAD-likecd07516:HAD_Pasecd07517:HAD_HPPcd07518:HAD_YbiV-Likecd07519:HAD_PTasecd07520:HAD_likecd07521:HAD_FCP1-likecd07522:HAD_cN-IIcd07523:HAD_YsbA-likecd07524:HAD_Pasecd07525:HAD_likecd07526:HAD_BPGM_likecd07527:HAD_ScGPP-likecd07528:HAD_CbbY-likecd07529:HAD_AtGPP-likecd07530:HAD_Pase_UmpH-likecd07531:HAD_Pase_UmpH-likecd07532:HAD_PNPase_UmpH-likecd07533:HAD_likecd07534:HAD_CAPcd07535:HAD_VSPcd07536:P-type_ATPase_APLTcd07538:P-type_ATPasecd07539:P-type_ATPasecd07541:P-type_ATPase_APLT_Neo1-likecd07542:P-type_ATPase_cationcd07543:P-type_ATPase_cationcd07544:P-type_ATPase_HMcd07545:P-type_ATPase_Cd-likecd07546:P-type_ATPase_Pb_Zn_Cd2-likecd07548:P-type_ATPase-Cd_Zn_Co_likecd07550:P-type_ATPase_HMcd07551:P-type_ATPase_HM_ZosA_PfeT-likecd07552:P-type_ATPase_Cu-likecd07553:P-type_ATPase_HMcd16415:HAD_dREG-2_likecd16416:HAD_BsYqeG-likecd16417:HAD_PGPasecd16418:HAD_Pasecd16419:HAD_SPScd16421:HAD_PGPasecd16422:HAD_Pase_UmpH-likecd16423:HAD_BPGM-like
CD Hierarchy
Imported CD
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