cl15456: ADAM_CR Superfamily (this model, PSSM-Id:326582 is obsolete and has been replaced by 472809)
ADAM cysteine-rich
ADAMs are membrane-anchored proteases that proteolytically modify cell surface and extracellular matrix (ECM) in order to alter cell behaviour. It has been shown that the cysteine-rich domain of ADAM13 regulates the protein's metalloprotease activity.
Jiyao W et al.(2023). "The conserved domain database in 2023.",