Conserved Protein Domain Family

cl00470: Aldo_ket_red Superfamily 
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Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial applications. Members have very distinct functions and include the prokaryotic 2,5-diketo-D-gluconic acid reductases and beta-keto ester reductases, the eukaryotic aldose reductases, aldehyde reductases, hydroxysteroid dehydrogenases, steroid 5beta-reductases, potassium channel beta-subunits and aflatoxin aldehyde reductases, among others.
Accession: cl00470
PSSM Id: 320990
Name: Aldo_ket_red
Created: 8-Feb-2008
Updated: 5-Dec-2016
Curated CD Hierarchy
CD Hierarchy
Imported CD
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