Conserved Protein Domain Family
BPI

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cl00188: BPI Superfamily (this model, PSSM-Id:320805 is obsolete and has been replaced by 412206)
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BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative bacteria.; Apolar pockets on the concave surface bind a molecule of phosphatidylcholine, primarily by interacting with their acyl chains; this suggests that the pockets may also bind the acyl chains of lipopolysaccharide.
Links
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Taxonomy: root
PubMed: 16 links
Protein: Related Protein
Related Structure
Statistics
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Accession: cl00188
PSSM Id: 320805
Name: BPI
Created: 8-Feb-2008
Updated: 19-Sep-2018
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