Conserved Protein Domain Family
ELYS

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pfam13934: ELYS 
Nuclear pore complex assembly
ELYS (embryonic large molecule derived from yolk sac) is conserved from fungi such Aspergillus nidulans and Schizosaccharomyces pombe to human. It is important for the assembly of the nuclear pore complex.
Statistics
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PSSM-Id: 316456
View PSSM: pfam13934
Aligned: 114 rows
Threshold Bit Score: 91.4851
Threshold Setting Gi: 0
Created: 28-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam13934 is a member of the superfamily cl16486.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122105288   725 FPDDALKkmwiennStGVYPPNSMQNLLRTLLv-----PnvNTEMKYVLLCYTFMDmtavlge-------gryagivQNL 792
41_pfamImport    3 FFDRLLLlas-isnHkKLYPPTNLNVLKSLLDsi--dtCpfDSLKKNCLIYYLLKEygd----------------krE-- 61
77_pfamImport    3 FIDHLLQlae--peGsLQYPPADDAELFQLSSrlaalsAssTGLTARSCLYYVSLAfsp----------------spEAA 64
96_pfamImport    3 YIDELLLdle--ldGtDLYPPTSLSELDSLLCavl-daPdgDLIRTHSVIYYILLAvcdg--------------tesTVP 65
6_pfamImport     3 IFDCILIsgg-vrdPdFIYPPHDVAGLTRLLDaias--ssyDTLKKQTLVYFLLKWhqd----------------grE-- 61
68_pfamImport    3 IFDILLRsgs-vrsPdILYPPHNEQSLLRLLEaiek--snyDTLKKDCLVYFLLKWhqd----------------grE-- 61
98_pfamImport    3 LFDILLSfgs-ikePdGLYPPANAEVLQRLLDeis-ksNtyDALKKDCLVYYLLKWhrd----------------grE-- 62
61_pfamImport    3 FFDELLTfas---vdaSMYPPRSEGQLSSLLKaif-gaTtlDYLKQLSLVYYLLLDldaytqhiandqgsggaapsaSAA 78
35_pfamImport    3 FFDELLSfaa---vdtSLYPPRSEHQLSQLLTaif-aaTslDYLKQLSLVYYLLLDldahsqrdsm--hqdgasspsSAA 76
99_pfamImport    3 FFDELLSfas---vdtSLYPPRSSQQLSHLLTaif-aaTalDYLKQLSLVYYLLLDldayseras----idegkptsRAS 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122105288   793 IKFPS--VFKLSSALIKRTQAFWFLDHG-HIDGAIEELlsPMSQSeQFPHwqreFLISALLRY---------DASHLALR 860
41_pfamImport   62 DAFAS--DKLIPSHFTTGIDGLWALDHS-MWQLAIHCFatPTVSP-DFVP----DIMLSLATLpp-----ikQRAKHLLR 128
77_pfamImport   65 AAVAK--DLLLPPAFRLSVRAFHALDSG-EYCTAVRLLadPRVTP-DFVP----RTLAILTTLpe-----psERAELVLS 131
96_pfamImport   66 DHFARasEFILPLGTTKTVQGGFALDTG-SWQRAIAALsdPHVVP-DRSS----ETLAVLSTCpp-----ieQRASYVLS 134
6_pfamImport    62 DKFRL--QCSIPPQFTALADAYWYVDSGiNIGKGVSLLsdSRLNR-DHAS----KIMQAIALSp--------QSGPLLRK 126
68_pfamImport   62 DRFAM--QKSLPPQFTILADAYWHLDSGiNVARGVSILadARLNR-DYAS----KILHAISLSs--------DAHALIRR 126
98_pfamImport   63 ARFQR--DRSIPPQFVALADAYWYLDSGsDVARAVSLLsdPRLNR-DYAS----KILQAISLSk--------DPHPLIVK 127
61_pfamImport   79 EQFAD--NFVVLPQFTDAMQGYWLLDND-QYEQALPLL---AVA--DFIP----KIVRTLYLPsanekrsdvARAKLLLR 146
35_pfamImport   77 ERFAD--AYVVLPQFTDAMQGYWLLDND-QYDQAVPLL---AVA--DFIP----KIVRTLFLPspseqrsdvARAKLLLR 144
99_pfamImport   75 ERFAD--TYVVLPQFTDALQGYWLLDND-QYQQAIPLL---AIA--DFIP----KVIRTLFLPspsehrsdvARAKLLLR 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122105288   861 ALRVPG---MPISPFL-----------ELRTLLENNLISEAFKLQR---SKH---DK-----------KLLKCFFEGTLR 909
41_pfamImport  129 FYQLVNp--TLDLHTAi---------lVLRAMSASGQIRTAWALQR---TFQ---RPdr--------dQLIHTILEACFG 183
77_pfamImport  132 YWRLARidlAAYGKDEvkc-----vlrALCAPERARGVAEAWSLAR---EWR---EEge-------reELAGTVLETCFG 193
96_pfamImport  135 FWRLKGi--TLSDPNDlaf-----ildALCDATRKRGVVEAWALQR---QWI---DEtq-------rdELANRVLSQCFG 194
6_pfamImport   127 YIRTACp--ALVEPPDv---------lRYLIALAESSLFEAWSFQR---TFS---EThel------rpRLFRKLLDWALY 183
68_pfamImport  127 YVRTAKp--PLMEPDDi---------eLYALALAESSLLEAWQFQR---TFH---ESnev------rpRLMQKLLEWCVA 183
98_pfamImport  128 YIQTAKp--LLAEPDDl---------dTYTLALAHSNFFEAWQFQR---TFN---QRdpt------raRLLKKLFEWCVN 184
61_pfamImport  147 FLRTSN---QVTSSPSgsepflqevemQIQALCFVSGPARAFSEIRa-lTSSi-qDDeqrrv--siraRLIFKVLEHCFA 219
35_pfamImport  145 FLRTSN---QATSSAPgsesflqeiemHIQALCFVSGPARALSEIRa-iTSTi-qDDeqqrv--svraRLIFKVLEHCFA 217
99_pfamImport  143 FLRTSD---RDSASAGtseakveelemEIQALCFVNGPAHALAEIRaiaTSDvpfDDeaehvrvamraRLIFKVLEHCFA 219
                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 122105288   910 s--------SNY-EVLLDLAMSEEETRILREYLTST 936
41_pfamImport  184 lndhakpysASL-QILSSFPFDPLEDSILEQFCRSS 218
77_pfamImport  194 dnhaghplgSHL-SALLALPFTPSEDALATSFCSSP 228
96_pfamImport  195 nnslgkpvaHHV-RALLAHPFTSREDALADAFCRSP 229
6_pfamImport   184 pip----qpKAL-KELISLPLSKYEETLLNDYATKP 214
68_pfamImport  184 pkp----rpSAL-MQLLSLPLSKFEESILHSYVLRP 214
98_pfamImport  185 ptp----rpTAL-TQLLSLPLNHYEQEVLATYAATP 215
61_pfamImport  220 pp------rSAAiQNLLACSLDPEEEVTLESFVLSP 249
35_pfamImport  218 pp------rSSAiQNLLGCSLDPEEQVTLESFVLSP 247
99_pfamImport  220 pp------rSAAiQNLLGCNLDAEEELTLESFVLSP 249
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