Conserved Protein Domain Family
HutI

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COG1228: HutI (this model, PSSM-Id:31421 is obsolete and has been replaced by 224149)
Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]
Statistics
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PSSM-Id: 31421
View PSSM: COG1228
Aligned: 45 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 7-Oct-2002
Updated: 7-Oct-2002
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16126215  34 EKAEIKPLPKGLDGQASTGFPStykplparatafvgatvltaTGQQIDnGVVFVSEGKITAVGGPD---TPIPAG---IV 107
gi 11498526     --------------------------------------------------------------------------------
gi 15896575   1 ------MKKAMLLIKNGKILTM--------------------TGVNYDsGSVLIDNGKIIKVGEN----IDVDES---CE 47
gi 16126216  12 CALAFPAAAETVAIVNARLEPVs-------------------SPAIPN-GTLVIKDGKIAALGAS----IQVPAG---AR 64
gi 19704736   1 MSYILLKNCRELLTIEENAKD---------------------LIGLKNnTSLLIENERIKKIGTYEdlkKEISSNn--FQ 57
gi 15839453   5 SISQVSARPGRIGIRARQMFDG--------------------YRFQRGpVLVVVEDGRISAVDFAG----SACPD---MN 57
gi 14589970   1 ----------MKAVKATLMYDG--------------------LGNIEK-NVYIIFDKDIVNITRE------KPKD----- 38
gi 1723032    2 KRVDTIRPRSRAVRLHVRGLG---------------------LPDETA-IQLWIVDGRISTEPVAG-------------A 46
gi 16263373  28 EALFLLARPVFTLLRSGREMLAaalvlglcatasaddvlfenVRIFDGkGAVLSAPSNVLVKGNVIaaiSTSPIEgegAE 107
gi 21362609   5 LPGDTVWRNIRLATMDPQQQAL--------------------YGLVDN-QALIVREGHICDIVPETqlpVSGDN------ 57
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16126215 108 VIDAKGKWITPGIVDAHSHLGVYPSPGVSARSDgnEATDPNTAQVWAEHSVWPQDPGFNRARAGG-----VTTLLVLPGS 182
gi 11498526   1 ------------------------------------------------------------------------------MA 2
gi 15896575  48 IIDADGFWVMPGIIEAHCHVGIQEEKRGFEGNDcnEMTNPVTPYLRALDGINPMDSAFYTALTAGi---tGIMVGP--GS 122
gi 16126216  65 VIDAKGGVVTPGLIAPSSNLGASEISGVRETRDd-GTGSALSAAFDISYGVNPASTFLGLARDGGitgsaVTPVLSGTGG 143
gi 19704736  58 EIDCSDKVVMPGYVDCHTHLIFGESRVDEYVASf-TMTKNEIKNKIVRTGIEASIFSTRNATDEEli-nsSLIKLNRMLK 135
gi 15839453  58 LVDLGESTLLPGLVDAHAHLCW-DPDGRPEDLa--GDPHAVLVGRARRHAAAALRSGITTIRDLGdr-dyAALALREEYR 133
gi 14589970  39 VEVVAEGVVTPAFIDAHSHIGMDRYGEPYQESElnEQMDSVLPLADALYSIYMDDKAFKHSIEFG-----VLYSSILPGS 113
gi 1723032   47 DTVFDGGWILPGLVDAHCHVGLGKHGNVELD----EAIAQAETERDVGALLLRDCGSPTDTRGLDdh--eDLPRIIRAGR 120
gi 16263373 108 RIAGDGRTLMPGLIDAHWHAMLAASSPAEAMG-----DVSFASILAGEEATDTLMRGFTTVRDLGg----PAFGLKRAID 178
gi 21362609  58 IHDMQGRLVTPGLIDCHTHLVFAGNRAAEWEQR--LNGASYQHISAQGGGINATVSATRACAEETly-llARERMMRLAS 134
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16126215 183 ANLFGGRSVTLKNVPSLTMQGMKFPGAPYG--LKMACGENPK-------RVYGGRGRSPSTAMANVFGFRKaWIDAADYA 253
gi 11498526   3 SGYPLSQTFGHGDIHFLPPELADARTSKIK------VPFQSL-------LCDGEDEFRKGARYVLREGVDF--IKIFVTG 67
gi 15896575 123 ANVVGGQWMFLKTYGRAIDKMVVLQPSAMK----IAFGENPK-------ANYDKKNMMPSTRIAIAAMLRE--ELFEAQQ 189
gi 16126216 144 GAHEHADDGVVEEMTAGAHGDGDPPLFGGQaaFIRLKAGSPDivearklAVTVSLGESGARAAGGSRGANLvLLRSALED 223
gi 19704736 136 HGTTTVEIKSGYGIDMETEIRLLKLINILKekSPQTILSTYLg--------A-HYFDTKMGKEKYIDFMINeVMPVIKKE 206
gi 15839453 134 QKTTVGPELVVSGPPLTRSGGHCWFLGGVA---------------------DSVEELVDAVQERAARGADW--IKVMATG 190
gi 14589970 114 GNIIGGKGVLIRNYGRDIEDAFIKYVGVKA-----AFGYNPR-------STTNWKGLRPSTRMGAIGILFNwLIKTKKTI 181
gi 1723032  121 HLARPKRYIAGFAVELEDESQLPAAVAEQA---------------------RRGDGWVKLVGDWIDRQIGD-LAPLWSDD 178
gi 16263373 179 QGIIPGPRIYASGAMITVTSGHGDFRQLTDlpRRTGGLLTPMetvggamVVDSPDEVRLRVREQFMQGAVL--IKLTAGG 256
gi 21362609 135 EGVTLLEIKSGYGLELATEEKLLRVAAKLAaeNAIDISPTLL-------AAHATPAEYRDDPDGYITLVCEtMIPQLWQK 207
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16126215 254 R--KWDDYRAKVAKGEKADAPKrdlqMETLAGVLKGEILVQNHCYRAD----EMAVMIDIAREFGYKITMFHHAIESYKL 327
gi 11498526  68 G--VASQKD-KPEFPQMTRGEI----AAVVEEARRAGRLVHAHAESSE----GYINAVEEGVKTLAHGMDLNQDAINLSV 136
gi 15896575 190 Y--YEKRKNAEKSGDSFNKEFR----KECWVPVFDKKIPLKAHVHRAD----DILTAIRI-AKEFNLNLTLDHCTEGHLV 258
gi 16126216 224 AraFASRRAAFEQGATRDFGLSrl-dLQALIPVVQGKTPLLIRVSRAAdirqALKFAAEERIKIVLEGVEEGWMVADEIA 302
gi 19704736 207 N--LAQFCDVWCDEGYYNAEDC----YKILKAGLENDMLPTLHTECYSai-gGAKVAAELKAANVGHLNYISSEDIKLLK 279
gi 15839453 191 G--FVTTAS-DPWQPQYGSGQL----AAVVAAAEQVGLPVTAHAHATA----GIAAAVAAGVDGIEHCTFLS-EGSAAAS 258
gi 14589970 182 S--LLEKGK---KDPEEIDPVI-----EALIPVLKGEMPLRVHAHKEDdi-aVLLMIKRKFNLKVTVEHAADVHSKETFE 250
gi 1723032  179 V--LKAAIDTAHAQGARVTAHVf--sEDALPGLINAGIDCIEHGTGLT----DDTIALMLEHGTALVPTLINLENFPGIA 250
gi 16263373 257 G--VSSPFS-PLDVTTFTEPEL----RAAVEIAENWGTYVAAHAFTSD----AIRKAIAAGVKCIEHGFLMDEATARLIA 325
gi 21362609 208 G--LFDAVDLFCESVGFNVAQS----ERVLQTAKALGIPVKGHVEQLSll-gGAQLVSRYQGLSADHIEYLDEVGVAAMR 280
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16126215 328 APv---------------LAKEeiCsATWASWTGFKMESLDGIDanAAILAKNGACVVIHSDDPIMTQr--lNQEAAIAM 390
gi 11498526 137 EKdvtliptlsivdvalkFGPSnnL-PEWMLEKLKEVHEIHAES--IKRAYRERVRLATGTDFFIGAKevqlYGLNSLEI 213
gi 15896575 259 Akeikes------gfpaiVG------PTLTSRNKIETQYADFKT--AGILHNEGVKVAITTDHPVTR-----IQDLLICA 319
gi 16126216 303 K-----------------AGVPviLdPQDDLPGSFETLGSRLDN--AARLHAAGVSVAINGSRDFNN-----LRQERLNA 358
gi 19704736 280 EAn---------------------VvGVLIPSTDFSVKHKKPFV--PKPMLDEGMTIAIATNLNPGNw----VEDMNISM 332
gi 15839453 259 Pdvveaiv---aqgvwcgMTIPrvY-PEMPENLVAVVQDGWRN---IRRLIDAGARVALSTDAGVAPGr--rHDVLPDDL 329
gi 14589970 251 KIk--------------rEGVPlvYgPLDAHPYKVELKHEDWKN--AKYLLEVKPFFGLMSDHPFSIQ-----ANLYLQL 309
gi 1723032  251 D-----------------AAGR--Y--PTYAAHMRDLYARGYGR--VAAAREAGVPVYAGTDAGSTIE----HGRIADEV 303
gi 16263373 326 ENdiwlslq--plpelmrTGLRd---GSVERAKADEVWPGIGRT--YELAKRYKIKTAWGTDVLFSR-----ALAKQQGA 393
gi 21362609 281 D-----------------GGT---V-GVLLPGAFYFLRETQRPP--VELLRRYQVPVAVASDFNPGTSp---FCSLHLAM 334
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16126215 391 TAGAKLGinIPRAEAIKWITANPAKAMGIG-------DKTGSIEPGKAADLVVWSRDPFSVYaQAEQVYIDGALTYDRKN 463
gi 11498526 214 KLLVGLG--VKPMDALKAVIKEGEIVKQS--------------------------------------------------- 240
gi 15896575 320 GLAAKEG--LGIEEGLKAITINPAEICNVA-------NRVGSIEVNKDADIAIFDGNP-------METFTKTMYTIINGE 383
gi 16126216 359 GLAVAHG--LPYPAALAAVTLVPARIWGQA-------DKVGSLEVGKLADVVVWNGDPLETTsWPTAVLIGGVEQPKDGR 429
gi 19704736 333 ILACRNHk-MTENEAIRATTLGGAKALKIE-------KDYGSLEVSKFADIQIRNSDSYKNV-VYKFGVNEIEHVIKNGK 403
gi 15839453 330 VYLSRHG--FTSTEVLTGATAAAAASCGLG-------HRKGRIAPGYDADLLAVAAGVDHD----PAGLCDVKAVWRSGT 396
gi 14589970 310 RHFIRLG--MSKAEAIKLITYNNAKILGIE-------DKLGSLEKGKWASLVVWNGDP-------FNLENYPTHVFAEGE 373
gi 1723032  304 AALQRIG--MTAHEALGAACWDARRWLGRP-----------GLDDRASADLLCYAQDPRQG----PGVLQHPDLVILRGR 366
gi 16263373 394 ILASLVRw-YTPAEALVMATATNAELLALSgqrnpypGKLGVIEEDALADLLLVEGNPLENIdLVADPANSFKIIMKDGV 472
gi 21362609 335 NMACVQFg-LTPEEAWAGVTRHAARALGRQ-------ATHGQIRAGYRADFVVWDAEQPVEI-VYEPGRNPLYQRVYRGK 405

                ....*...
gi 16126215 464 PRFQPKSD 471
gi 11498526     --------
gi 15896575 384 IVYSLKDK 391
gi 16126216 430 HEQLKARY 437
gi 19704736 404 IIF----- 406
gi 15839453 397 QVPLQASA 404
gi 14589970 374 LIHEANL- 380
gi 1723032  367 TFGP---- 370
gi 16263373 473 IYKNTLTP 480
gi 21362609 406 IS------ 407
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