Conserved Protein Domain Family
NMDAR2_C

?
pfam10565: NMDAR2_C 
N-methyl D-aspartate receptor 2B3 C-terminus
This domain is found at the C-terminus of many NMDA-receptor proteins, many of which also carry the Ligated ion-channel family pfam00060 further upstream as well as the ANF_receptor family pfam01094. This region is predicted to be a large extra-cellular domain of the NMDA receptor proteins, being highly hydrophilic, and is thought to be integrally involved in the function of the receptor. The region also carries a number of potential N-glycosylation sites.
Statistics
?
PSSM-Id: 313729
View PSSM: pfam10565
Aligned: 14 rows
Threshold Bit Score: 698.105
Threshold Setting Gi: 47209023
Created: 27-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam10565 is a member of the superfamily cl11194.
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603   839 HLFYWKLRFCFTGVCSDRPGLLFSISRGIYSCIHGVHIEEKKK----SPDFN----LTGSQSNMLKLLRSAKNISSMSNM 910
gi 973184198  842 HLFYWRLRYCFTGVCSGTPGLLFSISRGIWSCIHGVHIEEKKK----SSDLD----FSSPQANMLKLIKSAKNMTTMSNL 913
gi 847165734  831 HLFYWKLRYCFTGVCTGTPGLLFSISRGIYSCIHGVHIEEKKK----SPDFS----FTASQTNMLKLLRASKNIANLSNL 902
gi 557015599  732 HLFYWKLRFCFPGVCSGKPGFLFSISRGIYSCIHGVHIEEkKK-----SEFD----F-SNQTNMLKLLRTAKTMTNMSNL 801
gi 992199778  837 HLFYWRLRYCFTGVCSGKPGLLFSISRGIWSCIHGVHIDMkKK----SSDLD----F-SPQANMLKLIKSAKQMTNMTNL 907
gi 47219645   729 HLFYWRLRYCFTGVCSGRPGLLFSISRGIWSCIHGVHIDMkKK-----TDLD----F-SPQDKMLKLIKSAKHMTNMSNL 798
gi 542248777  831 HLFYWRLRYCFTGVCSGRPGILFTISRGIWSCIHGVHIDMkKK----APELD----F-SPQANMLHLLKSAKSIAl---- 897
gi 768942870  832 HLFYWRLRYCFTGVCSGRPGLLFTISRGIWSCIHGVHIDMkKK----KPELN----F-SPQANMLHLLRSAKSVAl---- 898
gi 47209023   607 HLFYWQLRFCFMGMCSGKPGLTFSISRGIYSCIHGVQIEE-NKstidSPSSTmkknMNNTHSNILRLLRTAKDMTAVPGI 685
gi 551518921  929 HWFYWQLRFCFMGVCSGQPGFVFSVSRGIYSCIHGVQIEEkSSsalnSPSAT----MNNTHSNIMRLLRTAKNMASLSGV 1004
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603   911 NSsrmdSPKRAADFIQ-R--GSLIMDMVSDKGNLM-YS-DNRS---FQGKESIFGDNMNELQTF--VANRQKDNLNNYV- 979
gi 973184198  914 NAsrinSPKRATDYMH-G--GPMMMDMVVDKGNFL-YA-DNRS---YPPKEALYGETGSDLQTF--MGNRHKDNLNNYV- 982
gi 847165734  903 NQsqcnSPKRTSDYIQ-R--NSLLMDMVLDKGNLS-YS-DNRP---FQQKD-VYSENTYDLAML--SGNHPKDNLNNYV- 970
gi 557015599  802 NAsratSPKQTSDYVQ-R--GSLLMDMVVDKGGLM-YS-DNRs---FQPKEAHYGDNISEMQTF--ASNHHKDNLNNYV- 870
gi 992199778  908 SGsrvnSPKRAGEFMHsA--GPMIMDLMSEKGNFV-YT-DNRs---YAQKD-IYGDS-SDIQSY--LANRHKDHLNNYI- 975
gi 47219645   799 GGshmnSPKH--EFMHsA--GPMIMDMMAEKGNFI-YA-DNRs---YAPKDMIYGDN-SDLQSY--IANRHKDHLNNYI- 865
gi 542248777  898 -----pSPKRNTVVVQ-----PSILDMMSGKGNSL-HT-LPQkg------pgLYS-NAVGPQGFlsLSGRHKNLLNNAAp 958
gi 768942870  899 -----sSPKRNTVLLQ-----PSILDVMTGKGNSL-HS-LPPkg------pgLYS-NAAGPQGFlsLSGRHKNLLNNAAp 959
gi 47209023   686 NG----SPHAALEYSH-SgcDSAIYDIQEHRRSLVgHPiDCKsappYLPEDNMFSDYISDVERT--FGNLPLKDNNLYQd 758
gi 551518921 1005 NG----SPHSALDFIR-R--DSSVYDISEHRRSLAgHS-DCKp--pYMPEDNMFSDYISEVERT--FGNLHLKDSNLYQd 1072
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603   980 FQ-GQHPLT------LNESNPNTVEVAVSTEs--------------KANSRP------RQLWKKSVDSIRQDSlsqnpVS 1032
gi 973184198  983 FQ-GQHPLT------LNESNPNTVEVAVSADa-------------tPGTTKP------RQLWKKSVETLRQSQ-----GS 1031
gi 847165734  971 FQ-GQHPLT------LNESNPNTVEVAVSAEp--------------KLNSRP------RQLWKKSVETLRQNQ-----GS 1018
gi 557015599  871 FQ-GQHPLT------LNETNPNTVEVAVSSEt--------------KVNSKP------RQLWKKSVETLRQsq-----gS 918
gi 992199778  976 FQ-GQHPLT------LNESNPNTVEVAVSADa-------------aQTAAKP------RALWKKSVDTVRQsq-----gP 1024
gi 47219645   866 FQgGHHPLT------LNDANPNTVEVAVNANs-------------vQTNAKPp-----RTLWKKSVDTLRSVPpg--psP 919
gi 542248777  959 FP-GQPKAP------PHQTSPNKPQLSITNDngqtr-----ltgagLTASKP------RALWKKSVETLKTQPsvvspgH 1020
gi 768942870  960 FS-MQQKGP------SLQTSPNKPQLAVTNDngksr-----laglaGDASKP------RALWKKSVETLKTQPsvispgL 1021
gi 47209023   759 HYlHHHPASalgmsgPPPNRPRSLGSTSSLDggmfdcdslgggvapIFTTQPrpsmthRNTSKFDLIAGHTPAd-----S 833
gi 551518921 1073 HYlHHHGSTpgl-tgPPPNRPHSLGSASSLEggmfdcdslgggvapIFTTQPcsalthRNMSKFDLLSGQTPPsg---qS 1148
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1033 QRDEA--TAENRtHSLKS----------PRYLP-------------------------EE--MAHSDISETSNRATCHRE 1073
gi 973184198 1032 VQDTL--PPDPR-MSMKS----------QRYLP-------------------------EE--AAQSDISDCSSRAQSYKD 1071
gi 847165734 1019 VNENG--TEESk-PSTKN----------QRFLP-------------------------ED--GHFSDVSEASSRATCHID 1058
gi 557015599  919 LKEKV--PEEKR-HSVKN----------QRYIP-------------------------EE--VVHSDVSDTSSRATSHKN 958
gi 992199778 1025 --DTL--APDPR-LSMKS----------QRYLP-------------------------EE--AAHSDISDCSSRATSYKD 1062
gi 47219645   920 MPDML--MPDPR-MSMKS----------QRYLP-------------------------EE--TAHSDISDCSSRAASYKD 959
gi 542248777 1021 SPAp---ASGPGpPQMKS----------QRYLP-------------------------ED--PQHSDLSECSSRPPSHKD 1060
gi 768942870 1022 GPSSTp-TSGPGpPPMKS----------QRYLP-------------------------EEppPPHSDISECSSRPASHKD 1065
gi 47209023   834 NQVGFkgANVYGrFSFK---------------GgasstgliggqdrycvgggggsggdDG--NIRSDVSDISTHTVTYGN 896
gi 551518921 1149 FKGGL--PDVYGkFSFKGgassstyipgPSYCGgrg--------------------ddDG--NIRSDVSDISTHTVTYGN 1204
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1074 PDNS---KNHKTKDNF-KRSVASKYPKDCSEVER-TYLKTK--------SSSpr-------------------------- 1114
gi 973184198 1072 PDNNq--KHHKPKDNLkKRSMTSKYPRDCSEVEL-SYLKSKq-------GGS---------------------------- 1113
gi 847165734 1059 SENNn--KHHKSKDNLkKRSVSSKYPRDCSEVEL-SYLKLK--------HGSnr-------------------------- 1101
gi 557015599  959 ADNNk--KHHKPKNNFkKRSVTSKYPRDCSEVEL-SYLKSKq-------SSTr--------------------------- 1001
gi 992199778 1063 PDNN---KHLKPKDNLkKRSMTSKYPRDCSEVEL-SYLKNKq-------GGSgr-------------------------- 1105
gi 47219645   960 PENN---KHMKPKDNLkKRTVTSKYPRDCSEVEL-SYLKSKqvssgtnqAGRgg-------------------------- 1009
gi 542248777 1061 SDSMaarGGFKPINQLrKRGGGGGGAG----------------------GGGga-------------------------- 1092
gi 768942870 1066 SDSMgarGGFKAINQLrKRGSGA--------------------------GGGgs-------------------------- 1093
gi 47209023   897 LEGNn-kRRNQYRDSLkKRPASAKCRREQDEIELsGLRRRPhhh--tvhHHFphgpqahrkvspplerkrggggnsspfl 973
gi 551518921 1205 LEGNa-kKRKQYRDSLkKRPASAKSRRELDEIEL-GYRRKPyhishhhyHsqrsvsppllpserkr--gggggnnngnsy 1280
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1115 ---dKIYTIDGEKe--PGFHLDPPQFVENVTL-PENVDFPDPYQDPSE----NFRKg-DSTLPM---NRNPLHNEEGLSN 1180
gi 973184198 1114 ----KIYTIDTERe--LGLHTDQHHFRENRAL-PEDLEYSEMYQDHND----NYRKp-EPVIHL---NSSPLHADDITPN 1178
gi 847165734 1102 ---dKVYTIDGDKe--PSFIMDQPKYSENSP--DQDDDYPDVYQDHND----NYRKaeA--LQP---DRTPLHSEGRLPN 1165
gi 557015599 1002 ---dKIYTIDtvterepsFHIEPHYYREAVAi-PEdIDFPEIYQDHNE----NYRKp-EAVVHI---NRTPLHNEdslpn 1069
gi 992199778 1106 ---eKIYTIDsdr--elsLHSDPLHYRESRGlaADdLDFPEIYSDHND----NYRKcdQPIIHL---NSSPLHHTdadll 1173
gi 47219645  1010 ---dKIYTIDsd----lsLHSDPIHYRESRGpaADdLEYPEIFSDHSD----NYRKceQPIIHL---NSSPLHHTdsdlv 1075
gi 542248777 1093 ---sKIYSIDsdq---asLQSAPPYQRDSQGgsDEhPYPPDLFPPDSTyphtHSHQsdAPILQL---SASLLHHShsaea 1163
gi 768942870 1094 ---sKIYSIDsdq---asLQSAPPYQRDSQGggDDhTYPPDLFPPDSTyshaHSHQgdTPILQL---NASLLHHShsaea 1164
gi 47209023   974 frkeKENLRD--------FYADQFRSKEGKAk-WE-QE-----GGSGG----SGVGdgSSGAIC---------------- 1018
gi 551518921 1281 lfreKESVRD--------FYLDQFRPKEGVPq-WEhVDLTEGPGn-------------RDGGVPtctSLVPVEDF----- 1333
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1181 N-----D-QYKLYSKH-------------FTLKDKG----SPHSETSERYRQnsTH-------------CRSCLS----- 1219
gi 973184198 1179 Ne----N-KYNLYSKH-------------YSLKEKN----VSPHETNDRYKQ--TH-------------CRSCLS----- 1216
gi 847165734 1166 N-----DiQYKLFSKH-------------YSSKEKN----TSMSESNDRHRQnsTH-------------CRSCLS----- 1205
gi 557015599 1070 n-----ekkynLYSKH-------------YSLKEKN----FSPFEINDRLKQasTH-------------CRSCLS----- 1109
gi 992199778 1174 --------pdnaYNKH-------------YSVKDKN----ASPHESNDRFKQ--TH-------------CRSCLS----- 1208
gi 47219645  1076 --------peptYAKH-------------YNMKEKNl--sLSPHESIDRYKQ--TH-------------CRSCLS----- 1112
gi 542248777 1164 dlhslkdkkysTYT-H-------------SSVKEKVggsfEAPSAGPGTQSVrpGH-------------CRSCLT----- 1211
gi 768942870 1165 dlhslkdkkysTYT-H-------------SsgkekaggsfEAPSGGSGSQGVrpGH-------------CRSCLT----- 1212
gi 47209023  1019 ---------------KslvpvedflkgisRKPEGKCg--lVSAGQQAHTCWEkgGSglggggiaggdweCRNCHSvchhs 1081
gi 551518921 1334 -----------LKSKP-------------KKSDSKGgpgsgl---------------------aggeweCRNCRAsggkq 1368
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1220 --------NM-PTY-S-----------GHFT-MR-----SPF-KCDACL-RMGNLYDIDEDQMLQETGNPATg------- 1263
gi 973184198 1217 --------KV-PNY-S-----------GHFA-VR-----SPYnRCEACL-HMGNLYDISEDQMLQEAISPLNq------- 1261
gi 847165734 1206 --------NM-PNY-T-----------GHYT-AR-----SPY-KCDDCL-HIGKLYDIDEDQMLHEAANSMh-------- 1248
gi 557015599 1110 --------KM-PNY-T-----------GHFA-MR-----SPYnRCEACL-HMGELYDISEDQMLQEITGAIHp------- 1154
gi 992199778 1209 --------KV-PNYpT-----------GPYApMR-----SPYnRCEACL-HMGNLYDISEDQMLQEAILSPTmh------ 1256
gi 47219645  1113 --------KVtASYpPggsytsnvsasASAT--R-----SPYnRCEACL-HTANLYDINEDQLLTDPLGSPTlhhqqqqq 1176
gi 542248777 1212 --------KL-SGY-S-----------GLYT-VR-----SPQaRCDACA-HLGNLYDISEDHL-----HSHYshthphph 1258
gi 768942870 1213 --------KL-SGY-S-----------GLYT-VR-----SAQaRCDACT-HLGNLYDISEDHL-----HSHYshah--ph 1257
gi 47209023  1082 g--glgggSTcSASgA-----------GGTtsr---pssASCkRCDSCKiQPSNLYNISEDNNMVfagg--------kgs 1137
gi 551518921 1369 isihggggGYsSGMgC-----------GSSA-GGsrpssATCmRCEGCK-KTGNLYDISEDNN-----HPLEqmgggkgg 1430
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1264 -EQVYQQDWAQNNALQL------------------------QKNKLR-------ISRQHSYDNI-VDKPRELDLSR---- 1306
gi 973184198 1262 -DEMFSHYWPQTDGPHVq-----------------------KRNRLR-------LSRQHSFDNI-LEKPKDIDLGR---- 1305
gi 847165734 1249 sEDFYEHNWLENNALHFq-----------------------KKNKLR-------INRQHSCDNI--NKPREQDLGR---- 1292
gi 557015599 1155 -EevyghQWIQSDVaql-----------------------qkrNKLK-------LTRQHSFDNI-LEKPKEADLGR---- 1198
gi 992199778 1257 pDdafghYWPQTDGphv-----------------------qkrNRLR-------LSRQHSFDNImLEKPKEIDLNR---- 1302
gi 47219645  1177 aDemfglYWPQTDGphv-----------------------qkrNRLR-------LSRQHSFDNImLEKPKDVDVGR---- 1222
gi 542248777 1259 sAdmfthYLPQSELglvgegdglvshfeptpsspsplptsssaQHLQ-------LSRQHSYENVlPD-------GI---- 1320
gi 768942870 1258 sGdmfthYLPQSELglvgegdglvspfetspsspsalptsssaQHLQ-------LSRQHSYENViPD-------GV---- 1319
gi 47209023  1138 aGp----SQTQTQV-----------------------------QRRKlgpggrvLRRQHSYDTF-VDLQREGANRMgglg 1183
gi 551518921 1431 gGvgcmaAGPQAQSqa--------------------------qQRRKsggfgkqLRRQHSYDTF-VDLQKEESGGMgslm 1483
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1307 ------------------PS----------RSISLKDRE---RL-LEGNFYGSLFSV----------------------- 1331
gi 973184198 1306 ------------------PA----------RSVSLKEKD---RF-LEDSPYANMFSM----------------------- 1330
gi 847165734 1293 ------------------PP----------RSVSLKEKE---RY-IQDSPFAKFLIV----------------------- 1317
gi 557015599 1199 ------------------Pa----------RSVSLKEKD---RF-LDESPYANMFNI----------------------- 1223
gi 992199778 1303 ------------------Pa----------RSVSLKEKD---RF-LEDSPYANLFNI----------------------- 1327
gi 47219645  1223 ------------------Pa----------RSVSLKEKD---RFaTSDSHYANLFNM----------------------- 1248
gi 542248777 1321 ------------------Perqsq-ahphmRGLSLPDRDrerELtLDEGAYANVLTM----------------------- 1358
gi 768942870 1320 ------------------PerhsqpqhahmRGLSLPDRDr--ELtLDEGAYANVLTM----------------------- 1356
gi 47209023  1184 gsm---------sgpfpqP-----------RSVSLKEKD---RFiEGSSPYSHMFEsgl--------------------- 1219
gi 551518921 1484 gglgggmggpgmggmlppP-----------RSVSLKEKE---RYmEENSPFAHIFERhggserererdrdplfyggesqk 1549
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1332 -----------------PS--SKLSG--KKS-----------------SLFPQGLEDSKRSKSLLPDHTSDNPFL-HS-- 1370
gi 973184198 1331 -----------------KP--DKLFS--SKS-----------------MLFNHNLEESKRSKSLYPDHTSENPFL-HS-- 1369
gi 847165734 1318 -----------------PP--EKLLG--NNt-----------------ALFTDSLKESKRSKSLYPDNSSDNPFL-HS-- 1356
gi 557015599 1224 -----------------KP--EKLLS--SKA-----------------SIFnhnleeskrSKSLYLDHSSENPFM-HS-- 1262
gi 992199778 1328 -----------------KS--DKLFG--SRS-----------------MLFnhnleeskrSKSLYPDHTTDNPFM-QA-- 1366
gi 47219645  1249 -----------------RPysGRLFGtsSKS-----------------MMFnhnleeskrSKSLYPTHGSENPFLsYS-- 1292
gi 542248777 1359 -----------------RS--DRPLS--SRSppsps--------pshhHSLdtpmplprrSKSLFPDRPSHNPFL-QSap 1408
gi 768942870 1357 -----------------RS--DRPFS--SRSppsls--------pshhHSLdtpmplprrSKSLFPDRPSHNPFL-QSap 1406
gi 47209023  1220 ---------------hqRStgEKDLR--DRDravmggggggfsrgagtYSL---------SKSLYPDKVNQNPFI-PT-- 1270
gi 551518921 1550 gsgspfglfrggeglhrRSigERDMR--DRSlmegg--------ggaaFSL---------SKSLYPDRVNQNPFI-PT-- 1607
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14285603  1371 ---HRDD--Q---RLVIGRCPSDPYKHSL-----------Ps------QAVNDS-YLRSSLRSTASYCSRD--------- 1415
gi 973184198 1370 ---LRED--Q---RLVHGRSSSDIYKQLV-----------Pv------KSRNDN-NLRSSVKSTASYCSRD--------- 1414
gi 847165734 1357 ---YQET--Q---KLSHGRSSSDIYKQSS-----------Lt------KARNDN-YLRSSIKSTSSYSSRD--------- 1401
gi 557015599 1263 ---YHED--Q---QLVHGRSSSDIYKQs--------------------KarNDn-nLRSSIKSTASYCSRD--------- 1304
gi 992199778 1367 ---VRDD--A---RLVHGRSSSDIYKQLA-----------Pi------KtrNEn-nLRSSIKSTTSYCSRD--------- 1411
gi 47219645  1293 ---LRDDssS---RLLHGRSSSDIYKQLAvaspagiigvpPn------KtrNDannQRSSVKSTTSYCSRD--------- 1351
gi 542248777 1409 gtaQRDPasQattRMPQRNSAHELYKQRM-----------PvsltlgnHgnHHfnqHGGQVDQQAFYPPQE--------- 1468
gi 768942870 1407 dmtQRDPasQavtRLPQRSSAHELYKQRM-----------PlsltlgnHgsHHsnqHGGHIDHQVFYPQQE--------- 1466
gi 47209023  1271 ---FGDD--Q---CLLHGAKPYYVKKPQTq---------qPqqllnnsRggGD---FRTSMGAASYLPASAtagvmsnva 1330
gi 551518921 1608 ---FGDD--Q---CLMHGAKQYYLTKQQq----------qQqqvaqnsR--GD---FRSQLSATSYLPASAtagvmpnvp 1664
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 14285603  1416 SRGHNDVYIS-------EHVMPYAANKNNMY---------STPR-VLNSC--SNR-RVYKKMPSIESDV 1464
gi 973184198 1415 GRVPNDMYIS-------EHAMPYVANKTSAY---------SAPR-VLNSC--SNR-RVYKKMPSIESDV 1463
gi 847165734 1402 GRVPNDMCAS-------EYALPYVTSNNSVY---------SAPR-VVNSC--SNR-RVFKKMPSIESDV 1450
gi 557015599 1305 GRIPNDMYIS-------EHVMPYVANKNSVY---------SAPR-VLNSC--SNR-RVYKKMPSIESDV 1353
gi 992199778 1412 GRIPNDMYIS-------EHVMPYVANKPSAY---------SAPR-VLTSSqfSNR-RVYKKIPSLESDV 1462
gi 47219645  1352 GRIANDMYNK-------EHVTPYSANKTSAY---------PGQRgVLNSTqfNNR-RVYKKIPSLESDV 1403
gi 542248777 1469 PPV------V-------AYMVPPAASQPMSYv--------TAPR-ASSAG--GNRpRLYRRMPSIESDV 1513
gi 768942870 1467 PPV------V-------SYMVPPAASQPMSYv--------TAPR-VSSAG--GNRpRLYRRMPSIESDV 1511
gi 47209023  1331 PRFPKELCLGgagghigNHHG----SNKLLPggrdtlglgQGQR-SFNGA--SNG-HVYEKLSSIESDV 1391
gi 551518921 1665 PRFPKELSLGg-----mNHHGSMLAVGP--------------PR-PFNG---SNG-HVYEKLSSIESDV 1709
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap