Conserved Protein Domain Family
Cytokin_check_N

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pfam10407: Cytokin_check_N 
Cdc14 phosphatase binding protein N-terminus
Cytokinesis in yeasts involves a family of proteins whose essential function is to bind Cdc14-family phosphatase and prevent this from being sequestered and inhibited in the nucleolus. This is the highly conserved N-terminus of a family of proteins which act as cytokinesis checkpoint controls by allowing cells to cope with cytokinesis defects. These proteins are required for rDNA silencing and mini-chromosome maintenance.
Statistics
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PSSM-Id: 313605
View PSSM: pfam10407
Aligned: 38 rows
Threshold Bit Score: 81.0487
Threshold Setting Gi: 74582426
Created: 27-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam10407 is a member of the superfamily cl11066.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74610887    46 TRKFLHF-TKPENTLLQLADEIENRITKLYSNLniESFEILSLQDINHCDLDATYLVKDVF-S-MDNTVLVILKN 117
gi 74591272    28 YVKFLYL-VDRTANIESLEEGLITRFSKRYPRE--RKLRVLAFQNKDLCDLDPEFAVEDVF-NeSNDELRVLVDN 98
gi 74635905    58 AKRFLYLvSDPDETIEELADKLKATFMELYPHH--AKPCIDSIQDEAALDLDRRFLLREVF-E-DNSLVRMVLTQ 128
gi 74582426    16 DNQFMIL-FDPSSSISLLKEKVQETYKSLYPFE--SNINIRNIKNEESYDIPNEYLVGEIF-P-TNS--KVIVES 83
gi 354543462   28 AKKFLHL-IDPVKQIGELLDAVVAQFQRLYPEE--PAINVVKCQDKNQCDLDKDYQVEDVF-E-SNDEVRVIVDN 97
gi 149245664   34 MKKFLHI-TDSGNRISDLVREIIQHFAKLYPRE--KQITVANLQNEDLCEVDFDYKVLQVF-E-KNDLVRVIVDE 103
gi 448091524   28 SRKFLHL-TDPETSLEKVCGELTRRFKRLYPFE--EEILIENLQDDDKCDLDAEFKVSDVL-G-PGETLRVVIGN 97
gi 459368539   29 FVKFLYI-ANKEATIKSLEDGLVSRFSKRYPNE--RKLKILSFQDRDLCDLDPDFAVEDVFdD-QNNEIRVLANN 99
gi 255726662   28 YLKFLYL-VDPNSTIDELEEGLCKRFKRRYPKE--DDLIVFSYQDHELLDLDPEFEISDIF-DeQNNEIRILVDN 98
gi 294659262   28 SRRFLHL-ADSDSDLGKVCDELTKRYAKLYPDD--DKLAIMSLQDDDRCDLDPDFEAGEAL-N-SGDIIRVIVEN 97
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