1OP4


Conserved Protein Domain Family
Cadherin_pro

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pfam08758: Cadherin_pro 
Click on image for an interactive view with Cn3D
Cadherin prodomain like
Cadherins are a family of proteins that mediate calcium dependent cell-cell adhesion. They are activated through cleavage of a prosequence in the late Golgi. This domain corresponds to the folded region of the prosequence, and is termed the prodomain. The prodomain shows structural resemblance to the cadherin domain, but lacks all the features known to be important for cadherin-cadherin interactions.
Statistics
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PSSM-Id: 312332
View PSSM: pfam08758
Aligned: 17 rows
Threshold Bit Score: 104.724
Threshold Setting Gi: 223590198
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1OP4_A        31 LCKtgfpedVYSAVLPKD-VHEGQPLLNVKFSNCNRKRKVQyeSSEPaDFKVDEDGTVYAVRSFPLTAEQAKFLIYAQDK 109 house mouse
P24503        29 TCKpgfseeDYTAFVSQN-IMEGQKLLKVKFNNCAGNKGVRyeTNSL-DFKVRADGTMYAVHQVQMASKQLILMVTAWDP 106 chicken
P39038        30 ACKagfseeGYTALISPN-VLEGEKLLKVEFSSCVGTKGMQyeTNSL-DFKVGADGTVFATRELKIPSEQVAFTVTARER 107 house mouse
Q9WTR5        26 ECTpgfqrkVLHIHQPAE-FIEDQPVLNLTFNDCKGNEKLHyeVSSP-HFKVNSDGTLVALRNITAVGR--TLFVHARTP 101 house mouse
P33150        26 ECTpgfqqkVFYIEQPFE-FTEDQPILNLVFDDCKGNNKLNfeVSNP-DFKVEHDGSLVALKNVSEAGR--ALFVHARSE 101 chicken
P15116        31 LCKtgfpedVYSAVLPKD-VHEGQPLLNVKFSNCNRKRKVQyeSSEPaDFKVDEDGTVYAVRSFPLTAEQAKFLIYAQDK 109 house mouse
Q6R8F2        27 PCIpgfgaeSYTFTVPRRnLERGRVLGRVSFEGCAGLPRTVyvSDDT-RFKVHTDGVLTVRRPVHLHRPELSFLVHAWDS 105 cattle
Q9R0T4        31 SCRpgfsseVYTFLVPERhLERGHILGRVKFEGCTGRPRTAffSEDS-RFKVSTDGVITVKRHLKLHKLETSFLVHAWDS 109 Norway rat
P10288        36 LCKmgfpedVHSAVVSRS-VHGGQPLLNVRFQSCDENRKIYfgSSEPeDFRVGEDGVVYAERSFQLSAEPTEFVVSARDK 114 chicken
XP_002936044  32 gCQpgfssaDYTFSVNRReLERGRKLGKVNFVDCTTRKHGLfdVGDS-RFRVLPDGTVLVKRHVKLHSKDTKFIVSTWDA 110 western clawed ...
1OP4_A       110 ETQEK--WQVAVNL 121 house mouse
P24503       107 QTLGRweAIVRFLV 120 chicken
P39038       108 QSAEQwaAMVRLLV 121 house mouse
Q9WTR5       102 HAEDM--AEL-VIV 112 house mouse
P33150       102 HAEDM--AE--ILI 111 chicken
P15116       110 ETQEK--WQVAVNL 121 house mouse
Q6R8F2       106 THRK---LSTKVTL 116 cattle
Q9R0T4       110 SYRK---LSTKVTL 120 Norway rat
P10288       115 ETQEEwqMKVKLTP 128 chicken
XP_002936044 111 RGIK---HSTNIAV 121 western clawed frog
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