Conserved Protein Domain Family
GATA-N
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pfam05349: GATA-N (this model, PSSM-Id:310154 is obsolete and has been replaced by 461628)
GATA-type transcription activator, N-terminal
GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutation are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This family represents the N-terminal domain of the family of GATA transcription activators.
Links
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Statistics
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PSSM-Id: 310154
Aligned: 33 rows
Threshold Bit Score: 83.2617
Created: 23-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q61169       147 MYQTLAALSSQGPA--AY-DGAPGGFVHSaaaaaaaaaA--A-SSPVYVPTTR-VGSMLSGLPYLQGAGs---------- 209 house mouse
NP_001016949   1 MYQSIAMAANHGPP--AY--EGAGGYMHS---------AtaA-TSPVYVPTTR-VSSMIPSLPYLQTSGs---------- 55  western clawed ...
XP_006642996   1 MYQGIAMTTNHGAP--SY----ESRFMHS---------A--AaTSPVFVPTTR-ATPMIPALPYLQPHAa---------- 52  spotted gar
XP_007238766   1 MYQGLTISATHHAAh-SY-EASFLPSVGS---------T--A-RSPVYVPSPR-VPAVLPALPYLQAHGa---------- 55  Mexican tetra
XP_002194999   1 MYQTLAISAAQGPT--PY-DGSPGGFMHS---------T--P-SSPVYVPTTR-VGSMLPTLPYLQGSGa---------- 54  zebra finch
XP_003757975   1 MYQSLAMA-NHGPPpgAYeTGGPGAFMHGa-------gA--T-SSPVYVPTPR-VPSSMLGLSYLQGGGsgaagsgpggs 68  Tasmanian devil
AAL55827       1 MYQSLAMAANHGPPpgAYeAGGPGAFMHGa-------gA--A-SSPVYVPTPR-VPSSVLGLSYLQGGGagsasggasgg 69  human
XP_005044495   1 MYQSLAMAANPGPP--AY--EGAGGFMHSa--------A--A-ASPVYVPTTR-VTSMLPSLPYLQSSAs---------- 54  collared flycat...
XP_008120695   1 MYQSLAMAANHGPP--SY--EGASGFMHSa--------A--A-ASPVYIPTTR-VTSMISSLPYLQGSAs---------- 54  green anole
XP_010743676   1 MYQGI-MTTNHGPP--SY----EAGFLHNa-------sA--G-TSPVYVPTTRvVTPMIPALPYLQTPGa---------- 53  large yellow cr...

Q61169       210 ----------------GPSNHaGGAgaHPGWS-Q---------ASADS-P-PYGGggaagggaagpggagsATAH-A--- 257 house mouse
NP_001016949  56 ----------------SQQGSpVs--gHNMWA-Q---------AGAEP-S-AYNP----------------GTSH-Pp-v 87  western clawed ...
XP_006642996  53 ----------------SQQNSpVc--sHSGWA-Q---------STEEPvP-SYTT----------------GGSH-Qstm 86  spotted gar
XP_007238766  56 -----------------PHHGaSSSsaHSAWA-QdpgssssspPSSYS-A-GGSG----------------NTAHaPp-v 98  Mexican tetra
XP_002194999  55 ----------------AQPSHpGg--gHAVWS-Q---------PAAES-P-SYSSg---------------GGSH-P--- 85  zebra finch
XP_003757975  69 sssssagaapsgsgpaAQQGSpA-------WS-Q---------PGPEG-S-TYTP---------------------Ps-v 107 Tasmanian devil
AAL55827      70 s----sggaasgagpgTQQGSpG-------WS-Q---------AGADG-A-AYTP---------------------Pp-v 104 human
XP_005044495  55 ----------------SQQGSpVs--sHSIWT-Q---------PAAES-A-AYNP----------------GSSH-Pp-v 86  collared flycat...
XP_008120695  55 ----------------SQQGSpVs--sHSIWTpQ---------PGAES-V-AYNP----------------GSSH-Ps-v 87  green anole
XP_010743676  54 ----------------SQQSSpVs--sHSAWA-Q---------PGADS-VpSYN--------------------H-Sp-v 82  large yellow cr...

Q61169       258 SARFPY---SPSPPMAN--G--AARDp-GGYvaaggtgagsvsgggGSLAAM--GGRehQYSSLsaARPLNGTYhhhhhh 327 house mouse
NP_001016949  88 SPRFTF---SSSPPISA--A--SNRE--VPY---------------SSPLAIsaNGRe-QYG-----RALGATYs----- 132 western clawed ...
XP_006642996  87 SPRFTF---STSPPISA--AvaAVRDn-ATY---------------PSPLNIsaNGRe-QYGT----RGLGGSYh----- 135 spotted gar
XP_007238766  99 SPRFVF---SANSPLCS--G----------M---------------TGTLDTpaGG------Ar--GLGMGPSYhp---- 136 Mexican tetra
XP_002194999  86 SGRFPY---SPSPPVAN--G--ASREp-GAY---------------SNSL----GARd-QYSPL--ARPLNGSYp----- 130 zebra finch
XP_003757975 108 SPRFSFxxxXXXXXXAAaaA--AAREa-AAYgt------------sGAGGTAglGGRe-QYG----RPSFGGSYs----- 162 Tasmanian devil
AAL55827     105 SPRFSFpgtTGSLAAAAaaA--AAREa-AAYss------------gGGAAGAglAGRe-QYG----RAGFAGSYs----- 159 human
XP_005044495  87 SPRFSF---STSTPIPA--T--SSREaaAAY---------------SSSLNLsaNGRe-QY-----GRGFGSSYs----- 133 collared flycat...
XP_008120695  88 SPRFSF---ATSSPIAA--T--TSREv-AAY---------------SSSLSItaNSRe-QY-----ARNFGGSYs----- 133 green anole
XP_010743676  83 SPRFAF---STSPPLSsgva--tvrEtaASY---------------TSPLNIsaNGRe-HYG----ARSLSGSYh----- 132 large yellow cr...

Q61169       328 hPtYS-----P-YMAA-PLTPAW-------PAGPFETPVLHSLQGRaGAPLPVpRGPST 372 house mouse
NP_001016949 133 sP-YP-----A-YMSP-DMGATW-------TASPFDSSMLHNLQNR-AGPAAS-RHPNI 174 western clawed frog
XP_006642996 136 sP-YP-----A-YVSP-SMGGGW-------TTSPFDSSVLHSLQPG-GAPGTA-RHPSI 177 spotted gar
XP_007238766 137 sP-YP-----A-YVSP-GMGGTW-------AASHFDSSVLHGLQSG-DQNPVA-RHPDL 178 Mexican tetra
XP_002194999 131 gP-YT-----S-YVGP-QLAPAW-------PTAPFENSMLHCLQGR-AAPIPV-RAPSA 172 zebra finch
XP_003757975 163 sP-YPaaaaaA-YMTAaDMGASWaaaaaaaSAGPFDGPVLHSLPGR-ANPAT--RHPNL 216 Tasmanian devil
AAL55827     160 sP-YP-----A-YMA--DVGASWaaa-aaaSAGPFDSPVLHSLPGR-ANPAA--RHPNL 205 human
XP_005044495 134 sP-YP-----A-YMSP-EMATSW-------TSSPFDSPMLHNLQSR-GTPAAA-RHANI 175 collared flycatcher
XP_008120695 134 sH-YP-----AtYMSP-ELGSTW-------TASHFENPMLHNLPNR-GSPGAA-RHGNl 176 green anole
XP_010743676 133 sP-YP-----A-YMSP-NVGGTW-------PASPFDSPVLHGLQT--GAPPGttrhpnm 174 large yellow croaker
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