Conserved Protein Domain Family
KilA-N

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pfam04383: KilA-N 
KilA-N domain
The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.
Statistics
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PSSM-Id: 309501
View PSSM: pfam04383
Aligned: 138 rows
Threshold Bit Score: 41.1544
Threshold Setting Gi: 896479541
Created: 25-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 140237      15 LSYEDIEIIM-MK-ENEYINATRLCSSR---G----RDILDWMSKESSVELINELDRINRSCndYyd---yrGi----vL 78
gi 123607637   28 ISRSLHGSPVeQRqRDGYINATALSSAYklaTgk-rRDVAHWLELERTTETLNHLSSITGIP--V-------I------- 90
6_pfamImport    1 PRVESGEIIP-QRmSDGYINATALCKSV---G----KSYSDYRQLQSTNHFLNELKAQTGLSeqQ-------L------- 58
gi 123061249    8 PRVEEGEIIP-QRlSDGYISATALCKSV---G----KEFGNYHALKSTQDFIAELSLQTNLPkeQ-------L------- 65
28_pfamImport   1 EHEVQGSPVQ-QRaTDGYINATAMCRIA---G----KMWGHYRENAGNKAFLLALESDIGIPisE-------L------- 58
45_pfamImport   1 VRDFHGNAIN-QRaSDGYFDATAMCRAA---G----KRIDNYWRLDGTQEFLSALSDNTGFPikSsgsafpqKsvteqnQ 72
43_pfamImport   1 FLPIVEGVAI-TTdKEGRFNLNALHKASg--Lre-sKEPNKWLALKSTNELITELEATARSC------------------ 58
gi 125404      23 TLPVICGVEI-TTdRAGRYNLNALHRASg--Lga-hKAPAQWLRTLSAKQLIEELEKET--------------------- 77
gi 123654654    2 SALMIAGIEI-HQdQDGRFSLNDFHRAAg--Gen-rHKPSLWAENQQAQELIEEIGKAG--------------------- 56
gi 500211667    2 naltITGVAI-RTdAQGRYCLNDLHRAS---GgeakHQPANWLRMQQTTDLAAEMEKE---------------------- 55
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 140237      79 NV-----VSDSETSELYVHRDLILHISHWISPLFSLKVVKFINSYIQD 121
gi 123607637   91 ELyqsfrGSPENGGGTWIHPKLAVRFGIWLSDEFGYQVEQWVEEWVLK 138
6_pfamImport   59 IQqr--iGGEPSLQGSWVHPYLAINLAQWLSPAFAVKVSTWVHEWMSG 104
gi 123061249   66 IHii--rGGNAQQQGTWVHPYLAINLGQWLSVKFSVKVSQWVYEWQTG 111
28_pfamImport  59 VKsv--kGGDPRVQGTWVHPQVAIHLAQWLSPEFAVKVSKWVYDWLSG 104
45_pfamImport  73 VLiqiiqGGNPENQGTWIHPQVSVNLAQWCSPQFAVQVSEWVFELMTT 120
43_pfamImport  59 -GssinkQKGGANPGTFAHELLAISYAGWISPKFQLLVNQVFLDYKTG 105
gi 125404      78 -MqncivSFEGRGGGTFAHELLAVEYAGWISPAFRLKVNQTFIDYRTG 124
gi 123654654   57 -IpalrvARGGRAAGTYACKELVYAYAMWVSPVFSLHVIRTFDSAAAN 103
gi 500211667   56 VPhf-rgIQSKQGLGTFVVKELVYAYAMWISPAFHLKVIRAYDEMVSG 102
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