4FNQ


Conserved Protein Domain Family
Melibiase

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pfam02065: Melibiase 
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Melibiase
Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
Statistics
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PSSM-Id: 307952
Aligned: 10 rows
Threshold Bit Score: 568.178
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4FNQ_A       289 SFQTPEVVMVYSDQGLNGMSQTYHELYRTRLARGAFRDRERPILINNWEATYFDFNEEKLVNIAKTEAELGIELFVLDDG 368
P27756       283 SFETPVALITYTDKGLTDLTQESHNFIKRHIIPKNFANKERPILINNWEATYFDFNRSQLLGLADEARKLGIELFVLDDG 362 Streptococcus m...
Q9KAR4       290 SFQTPEVVMVYTDQGLNHLSQLYHSLYRSRLVRGNWRDRPRPILLNSWEATYFDFTEDSLVEFAKEGKKLGVELFVLDDG 369 Bacillus halodu...
Q5KXZ9       289 SFQTPEVVMVYSDQGLNGMSQTYHELYRTRLARGAFRDRERPILINNWEATYFDFNEEKLVNIAKTEAELGIELFVLDDG 368 Geobacillus kau...
Q03GR7       291 TFQTPEVLMVYTNKGLNAMSQAYHHLIRERVVRSEFKNQERPIVVNNWEATFFDFNEAKLKPIVDEAKQLGIEMFVLDDG 370 Pediococcus pen...
EHA28114     308 TLTSPECVAVYSDKGLGSVSRKFHRLYRNHLMKSKFATSDRPVLLNSWEGVYFDYNQSSIETLAEESAALGVHLFVMDDG 387
WP_007056897 311 SYDTPWLFGSYGD-GLNEIAARFHSYVRSL--HPRLFSHGRPVILNTWEAVYFDHNFDTLKALADKAADSGVERFVVDDG 387 Bifidobacterium...
Q03GR4       287 SFQTPEAVLTWTNTGFNGMSQVFHDFSYQL----MPSQTNIPSVLNTWETLTFAVSESKVQHLIEHAHQLGLQMLVLDDG 362 Pediococcus pen...
XP_006969319 305 TFSSPEAVAVFSTTGVGGMSRKFHNLYRKHLIKSKFATQMHPVLLNSWEGLGFDYNDTTILHLAQESADLGIKLFVLDDG 384
WP_107724260 297 SFQTPEVAMVYSTTGLNGMSQTYHDLLRDRVARSRYKHDLRPILINNWEATYFDFDADKIQSILDAAAPLGIEMFVLDDG 376 Lactiplantibaci...
4FNQ_A       369 WFGK---RDDDRRSLGDWIVNRRKLPNG---LDGLAKQVNELG--------MQFGLWVEPEMVSPNSELYRKHPDWCLH- 433
P27756       363 WFGH---RFDDNSSLGDWFVNEEKLGGS---LDSFIKEIHDRG--------LQFGLWFEPEMVSVDSKLYRAHPDWVIQ- 427 Streptococcus m...
Q9KAR4       370 WFGT---RNDDTTSLGDWFVNSEKLPNG---IEGLAEKIEALG--------LAFGLWFEPEMVNKESELFKKHPDWIIH- 434 Bacillus halodu...
Q5KXZ9       369 WFGK---RDDDRRSLGDWIVNRRKLPNG---LDGLAKQVNELG--------MQFGLWVEPEMVSPNSELYRKHPDWCLH- 433 Geobacillus kau...
Q03GR7       371 WFGH---RDDDNSSLGDWQVDHRKFPQG---LNHFVKYVHEQG--------LKFGIWLEPEMISYDSKLYQQHPDYLMQ- 435 Pediococcus pen...
EHA28114     388 WFGDkypRVSDNAGLGDWMPNPARFPDG---LTPVVQDITNLTvngtestkLRFGIWVEPEMVNPNSTLYHEHPEWALH- 463
WP_007056897 388 WFGS---RRDDTSGLGDWQIAQDVWPDGpksLKALADYVHAKG--------MEFGLWFEPEMVNPDSDVARNHPDWILSp 456 Bifidobacterium...
Q03GR4       363 WFVN---RNGENGQLGDWFVDPIKFPNG---LNPLAQQAHHHR--------MKFGLWVEPEMITTNSQLYQQHPDWVLQ- 427 Pediococcus pen...
XP_006969319 385 WFGVkhpRVSDNAGLGDWEANPKRFPQG---LPDFISDVTKLKvans-sdhLQFGLWFEPEMVNPNSTLYMEHPDWAIH- 459
WP_107724260 377 WFGH---RNDDNSSLGDWFVNRNKLPGG---LADISKRTHDKG--------MRFGLWFEPENISADSDLYRAHPDWVLG- 441 Lactiplantibaci...
4FNQ_A       434 VPNRPRSEGRNQLVLDYSREDVCDYIIETISNVLASAPITYVKWDMNRHMTEIGSSALPperqretaHRYMLGLYRVMDE 513
P27756       428 ADQREHTYSRNQLVLNLANPDVVAYIKTVLDKLLTENTIDYVKWDYNRNITNIGNGRTYletq-mqsHAYILGLYNIVSY 506 Streptococcus m...
Q9KAR4       435 VEGRSQSHGRNQYVLDFSRAEVVDAIYEMMAELLRKAPISYIKWDMNRHLTEIGSPAWPkerqqeiaHRYILGVYDLYER 514 Bacillus halodu...
Q5KXZ9       434 VPNRPRSEGRNQLVLDYSREDVCDYIIETISNVLASAPITYVKWDMNRHMTEIGSSALPperqretaHRYMLGLYRVMDE 513 Geobacillus kau...
Q03GR7       436 VPGRSPSPSRNQYILDLGRQAVRNNIFDQLDQLLKSKQIDYIKWDMNRHLSDIYSVALPperqgevyHRYVLGLYELLER 515 Pediococcus pen...
EHA28114     464 AGPYPRTERRNQLVLNLALPAVQDFIIDFMTNLLQDTGISYVKWDNNRGIHETPSPSTD--------HQYMLGLYRVFDT 535
WP_007056897 457 TAGRLPLQGRTQQVLDLTNPDAFDYIYGCMDQLVGELGIDYIKWDHNKLVTEPGSRRSGrp----avHAQTLAVYNIFKG 532 Bifidobacterium...
Q03GR4       428 YVDRTPITARHQLVLDLSQAAVRDHLITTLTNLVQNNQLDYLKWDMNRHLTQVGSTHLPaaqqgelyYRYVCGLYDILTR 507 Pediococcus pen...
XP_006969319 460 AGSYPRTLTRNQLVLNVALPEVQDFIIESLSNILSNASISYVKWDNNRGIHEAPYPGLD--------YAYMLGLYRVFDT 531
WP_107724260 442 VPDRGRTLSRNEYVLDFSQPDVVDNIFEQMTAVLDKVPIDYIKWDMNRNLTEVYSPHSDsthegetsHRFILGVYDLMER 521 Lactiplantibaci...
4FNQ_A       514 MTSRFPHILFESCSGGGGRFDPGMLYYMPQTWTSDNTDAVSRLKIQYGTSLVYPISAMGAHVSAVPNHQVGRVASLKARG 593
P27756       507 LTTKHDKVLFESCSGGGGRNDLGMMCYFPQVWSSDNTDAIARLPIQYGSSYLYPTISMGAHVSAVPNHQMNRHTPLTTRG 586 Streptococcus m...
Q9KAR4       515 LVSEFPDVLFESCASGGCRFDPGMLYYAPQTWTSDDTDAIERLKIQYGTSMVYPLSSIGAHVSAVPNHQVRRVTSLETRG 594 Bacillus halodu...
Q5KXZ9       514 MTSRFPHILFESCSGGGGRFDPGMLYYMPQTWTSDNTDAVSRLKIQYGTSLVYPISAMGAHVSAVPNHQVGRVASLKTRG 593 Geobacillus kau...
Q03GR7       516 LTTAYPHILFEGCSGGGGRFDAGMAYYMPQIWASDNTDAVARLTIQYGTSLAYPISLATAHVSVSPNQQTGRETSMSTRS 595 Pediococcus pen...
EHA28114     536 LTTRFPDVLWEGCASGGGRFDAGMLQYVPQIWTSDNTDAIDRITIQFGTSLAYPPSAMGAHLSAVPNAQTGRTVPFTFRA 615
WP_007056897 533 LKTAHPGLEIESCSSGGGRVDLGILEHADRIWVSDCVDPVERADIQRYTSLLVPPAMMGEHVGASPAHSTQRATSQELRM 612 Bifidobacterium...
Q03GR4       508 LKRACPKLIIENCSAGGGRFDFGMLPYTNQTWISDLTDPVDRATIENGFSYLFPPRIFSNHITASPNAQNGRITPFETRL 587 Pediococcus pen...
XP_006969319 532 LSSKFPNVRWEGCASGGGRFDPGVLQYFPHIWTSDDTDAVERIAIQFGTSLVYPPSAMGAHVSAVPNGQTQRTTSIAFRA 611
WP_107724260 522 LTKRYPQILFEGCSGGGGRFDAGLMYYMPQSWPSDNNDPIERLKIQYGTSLVYPISAITAHVGTSPDELLGRSTSMKMRG 601 Lactiplantibaci...
4FNQ_A       594 HVAMS-GNFGYELDITKLTETEKQMIKQQVAFYKDVRRLVQFG 635
P27756       587 HVAMM-GNLGYELDLAILTKNEKKAVANQIKHYKKIRSVVQFG 628 Streptococcus mutans UA159
Q9KAR4       595 NVAFF-GAFGYELDVTQLTDEEKENMKKQIAFYKEHRELIMFG 636 Bacillus halodurans
Q5KXZ9       594 HVAMS-GNFGYELDITKLTETEKQMIKQQVAFYKDVRRLVQFG 635 Geobacillus kaustophilus
Q03GR7       596 AVAAS-GVLGYELDLTQLSSADKQIVQKQVVQYKQIRPLIQFG 637 Pediococcus pentosaceus ATCC 25745
EHA28114     616 HVAMMgGSFGLELDPATVEGDE--IVPELLALAEKVNPIILNg 656
WP_007056897 613 AMAFF-GHMGIEWNLLKEPDEALAKLAVWVAEFKKHRDWFAId 654 Bifidobacterium longum
Q03GR4       588 QLACI-GQLGLELNPKQLAPSEQQLLRGALIKYQQLKSTFIKa 629 Pediococcus pentosaceus ATCC 25745
XP_006969319 612 HVAMMgGSFGFELNPAEMPEDDKAQIPGIIALAEKVNPIVVKG 654
WP_107724260 602 AVAMS-GTLGYELDAAQLSDADKQAVKRQVAFYKQHRELVQYG 643 Lactiplantibacillus plantarum
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