Conserved Protein Domain Family
Interferon

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pfam00143: Interferon 
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Interferon alpha/beta domain
Statistics
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PSSM-Id: 306620
View PSSM: pfam00143
Aligned: 119 rows
Threshold Bit Score: 118.039
Threshold Setting Gi: 847168544
Created: 11-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
pfam00143 is a member of the superfamily cl00092.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3WCY_I         6 LQLQERtNIRKCQELL-E-QLN--GK--IN---LTYRADFKIPMEMT-------Ek-mQKSYTAFAIQEMLQNVFLVFRN 68
gi 1708494    34 LRLHDSaFAWDSLQLL-R-NMA--PS--PTqpcPQQHAPCSFPDTLLd-----tN---DTQQAAHTALHLLQHLFDTLSS 99
gi 637262724  28 LLTRLReANQANLDVLhR-NMG--PS--ISqqcIDDVFSFSHREALGn-----iNv-sEEGNAKAAIQEVLQQTGHIFKQ 96
gi 565309716  15 LQRKLLkANKDNSNLL-SsNIR--PT--TPlqcMRSFVELSLEDIGKkimidmnDe-cQVDIAKTAVKEILQQIDVIFRQ 88
gi 157940257  51 LQPKQEyLNRQTLKTF-E-EMN--PPedYDescQYDSIELPNIDEIYs-----iSq-mEE--MVLAVRGVLNETMRFYMK 118
gi 847168544  27 LHPKQEyLNTQILKAF-N-EMMplKE--TEeicEEHPTDLPNTESTYs-----vSq-vEA--GALAVREVLNETMRFYMK 94
gi 971438893  27 LPLQQRrVIESSLQLL-D-KMG--RR--FPqqcLREKMSFRFPEQVLk-----pR---QKETVKVAIEEILQHIFYIFSK 92
gi 637262728  28 LLARLRqANKANLELLnS-KMN--ST--IPqqcIEGVFSFS-LKNKLpt----nRdvsEEENAKVAIQEVLQQTGHIFRQ 97
gi 823474262  34 LWTHDDsFPGDALRLL-Q-DMA--PS--HTqpcHLQEPPF-FPDTLLh-----pNl--HPHQAAATALRILQHLFHTLSS 99
gi 513228423  35 LRPQDAtFSHDSLQLL-R-DMA--PT--LPqlcPQHNASCSFNDTILd-----tS---NTQQADKTTHDILQHLFKILSS 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3WCY_I        69 NFSSTGWNETIVVRLLDELHQQTVFLKTVLEEK-QEERL--TWEms---sTALHLKSYYWRVQRYLKLMKYNSYAWMVVR 142
gi 1708494   100 PSTPAHWLHTARHDLLNQLQHHIHHLERCFPADaARLHRrgPRN------LHLSINKYFGCIQHFLQNHTYSPCAWDHVR 173
gi 637262724  97 NYTEMPWDEDSLRAFHAGLDQQSENLKSCLSA---------SPRiq---lTRLRVKKYFRSLSNLLKEKEYSRCAWEIIQ 164
gi 565309716  89 NHTELVWHEGSLRDFHIGLDQQIKMLETCGNAElEQVIT--SPRnrklqlTRLRIKRYFQRLSDFLKNKKYSLCAWEIVQ 166
gi 157940257 119 HHESMGCKQQAWERFQQLLYYQINQLEACIPETaENPVF------------NQTISDQYQALEQILQEKN-TACTRDIIQ 185
gi 847168544  95 HHESMGCKQQAWERFQQLLYYQIHQLEACVSQTeENDLLk------------eSISEEFNLLETMVLEKDNSACVWDFIH 162
gi 971438893  93 NLTLAAWDGAALEQFQNGLYQQIEKLEACIIKKqTQY----FWSke---vNRLKLKKYFQKIDSFLKEKQHNLCSWEISR 165
gi 637262728  98 NCTEMLWDEDSLRAFHAGLDQQSENLKSCLSASpRSRRIq---------lTSLRVKRYFRSLNDFLKEKEYNRCAWEIIQ 168
gi 823474262 100 NSTRQHWPSHARNLLLNKLQHHIHHLEQCLPDNaLLFKG--PRN------PLLTINKYFRDIHLFLHAHNHSACAWDHVR 171
gi 513228423 101 PSTPAHWNDSQRQSLLNRIHRYTQHLEQCLDSSdTRSRTrwPRN------LHLTIKKHFSCLHTFLQDNDYSACAWEHVR 174
                        170
                 ....*....|....*..
3WCY_I       143 AEIFRNFLIIRRLTRNF 159
gi 1708494   174 LEAHACFQRIHRLTRTM 190
gi 637262724 165 IQVKQCFLWIEKIIQei 181
gi 565309716 167 IQIEACFQLINHYIQRI 183
gi 157940257 186 SEIRGNLQLVGQLASra 202
gi 847168544 163 LETRRNLQQVLQLSSRL 179
gi 971438893 166 AEMRRCLQLIDKVIRKL 182
gi 637262728 169 IQVKQCFLWIEKLiqei 185
gi 823474262 172 LEARASLRHLHNLTRAR 188
gi 513228423 175 LQARAWFLHIHNLTGNT 191
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