Conserved Protein Domain Family
ThrB

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COG0083: ThrB (this model, PSSM-Id:30432 is obsolete and has been replaced by 223161)
Homoserine kinase [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 30432
View PSSM: COG0083
Aligned: 41 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 7-Oct-2002
Updated: 7-Oct-2002
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
125396     2 VRAFKIKVPASSANIGPGYDVLGVGLSLFLELDVTIDSSqaqetnddpnncKLSYTKESEGYSTVPLRSDAnLITRTALY 81  baker's yeast
1730046   10 GLVASAVVAASSANLGPGFDSVGLALSLYDEIIVETTds------------gLTVTVDGEGGDQVPLGPEH-LVVRAVQH 76  Mycobacterium tuber...
14590921   1 -----------------------MAIDKPFDEVVVEEFNe------------FEIISSG---YPVPNGEDn-IALFSAKT 41  Pyrococcus horikoshii
20177964   1 MECKRARAYSSSANLGSGFDILSIAHTAFFDTVEICVENkn----------lNNIIVESN--SKIPLEPNKnSATYPIVK 68  Sulfolobus solfatar...
14194906   1 ---MKVLVPATTTNLGAGFDVFGLALDLFNEVEFSFDT--------------KETTIESTGKYASDLKDHN-LFFEVLRF 62  Thermotoga maritima
13541837   1 MELS-VISPCSSANLGPGYDVLAIAFDAFYDQVNVMLSDk------------LRILADE-----IPVQPDKnTAGLTALK 62  Thermoplasma volcanium
14194899   1 -MVVTVRAPATSANLGSGFDVFGVALSKPADVVRVERADt------------TTITVTGAGAQYVPTDPQE----NTAGV 63  Halobacterium sp. N...
14194902  18 AHQARAFAPASVANVAVGFDLLGYPMDQVGDTVTVRRIDt----------pQVRIAAIRGIAQPLPLQTERnTAGAALLS 87  Xylella fastidiosa
20177953   1 --MVKIYAPASIGNVSVGFDVLGAAVSPIDGTLLGDCVSvta-------aeRFSLHNEGRFVSKLPDDPKQnIVYQCWER 71  Yersinia pestis
14194909   1 ---MVVSVPATSANLGPGFDCLGLSLNLRNRFFIEPSn-------------IHAVKLVGEGEGIPKFLTNN-IFTKVFYE 63  Helicobacter pylori...
125396    82 VLRCNNIRNFpsgTKVHVSNPI-PLGRGLGSSGAAVVAGVILGNEVA-----QLGFSKQRMLDYCLMIER------HPDN 149 baker's yeast
1730046   77 GLQAAGVSAAg--LAVRCRNAI-PHSRGLGSSAAAVVGGLAAVNGLVvq-tdSSPSSDAELIQLASEFEG------HPDN 146 Mycobacterium tuber...
14590921  42 LFKMLNIEGG---LRIKLKKGIrPKS-GLGSSGASAVAG--ALGAAKllgvsNDELILKAAMKGEEKASGe----pHPDN 111 Pyrococcus horikoshii
20177964  69 IMEEIGIKAS---LKVRVIKGI-PEGLGLGSSGASAAAAVMAFNNLFnlnlsKEDLVRYAMY-GEIASSGs----pHPDN 139 Sulfolobus solfatar...
14194906  63 FERKTGYRVPp--VRIKQTCNI-PVSSGLGSSAAVIVAALHIANEGT-----GRNLSREDLMKLAVELEG------HPDN 128 Thermotoga maritima
13541837  63 MIEDFGIKDG---IKISIKKGI-PYGLGLGSSGSSAAAAAYAINNLFalgleRKDLIKYAAV-GELASSGs----pHPDN 133 Thermoplasma volcanium
14194899  64 VAAALDAP-----ATIHINKGVrPSS-GLGSSAASAAAATVALAELY-----DRPLDDDALVRAAAQGEAaasgvaHADN 132 Halobacterium sp. N...
14194902  88 MHRDLALPFG---FELEIDKGI-PLSSGMGGSAASCVAALLAANALL-----EEPLRREHLYRYALDGEAvasgsrHGDN 158 Xylella fastidiosa
20177953  72 FCQEMGKEi---pVAMVLEKNM-PIGSGLGSSACSVVAGLMAMNEFC-----GQPLDKVTLLGMMGELEGrvsgsiHFDN 142 Yersinia pestis
14194909  64 ILKKH-GNDGs--FKFLLHNKV-PITRGMGSSSAMIVGAVASAFAFL-----GFAFDRENILNTALIYEN------HPDN 128 Helicobacter pylori...
125396   150 ITAAMMGGfcgsflRDLTPQeveRREIPLAEVLpepsggedtglvpplpptdigrhvkyqWNPAIKCIAIIP---QFELS 226 baker's yeast
1730046  147 AAAAVLGGavv-swTDHSGD---RPNYSAVSLR---------------------------LHPDIRLFTAIP---EQRSS 192 Mycobacterium tuber...
14590921 112 VVPSYYGG------FTVIES---KSPLRVHFVDa-----------------------------KLRGVVVLP---EVEIP 150 Pyrococcus horikoshii
20177964 140 VAASVFGG------VVSVVS---VSPVKVVEIPi---------------------------nYSFDILLFTPlnvHIEEK 183 Sulfolobus solfatar...
14194906 129 VVPAFTGG------LVVCYQn--GSHLDFEKFE-----------------------------IDLSLTFLVP---NFPVC 168 Thermotoga maritima
13541837 134 VSASILGG------LVIVS----PEGISAKRIEv---------------------------sDQFKFLLVIAd-lKIRDK 175 Thermoplasma volcanium
14194899 133 VAPAILGG------FTIVRE----DGI--EHVD-----------------------------ASLALAVCLP---ETTVS 168 Halobacterium sp. N...
14194902 159 LGPLFLGG------LVLCTL----ERLVPVTVP-----------------------------AAWHSLLVHP---DTLLE 196 Xylella fastidiosa
20177953 143 VAPCYLGG------MQLILE---QEGYISQDVP---------------------------GFSDWLWVMAYP---GIKVS 183 Yersinia pestis
14194909 129 ITPAVFGGy----nAAFVEK----KKVISLKTK---------------------------IPSFLKAVMVIP---NRVIS 170 Helicobacter pylori...
125396   227 TADSRGVLPKAYPTQDLVFNLQRLAVLTTALTMDPpnADLIYPAMQDRVHQPYRKTLIPGLTEILscvTPSTYPGLLGIC 306 baker's yeast
1730046  193 TAETRVLLPAQVSHDDARFNVSRAALLVVALTERP---DLLMAATEDLLHQPQRAAAMTASAEYLr----LLRRHNVAAA 265 Mycobacterium tuber...
14590921 151 TAKARKILPSMVPLKDAVKNIAMASSLILALKEGD--LETIGRLLDDNLALPYRKKLMPWFDEIR---RVALETGAYGIT 225 Pyrococcus horikoshii
20177964 184 TKKAREMVPKTVTLSDYINNSRYISSLLLGFIKGE--RELIRLGLNDKIVEKARLPLFPYYPKIK---EVAIKYDAIGAC 258 Sulfolobus solfatar...
14194906 169 TNEMRKILPEKVPFEDAVFNIKNSCQFLAKIAAGK--IKEALKYVGDRLHQNYRINGNKKMKEFV---EAILSKNPEYWF 243 Thermotoga maritima
13541837 176 TKYARSLVPSGVSMGDHKRNTSRVASLIAGLMSGD--RELVSTGMNDDIVEAAREPIFPYYRRVK---DTAIESGAVGAV 250 Thermoplasma volcanium
14194899 169 TRDARGVVPESAAMEAVVSTVESAATLTLGMCEND--PQRVGRGVEDALVTPARARLMDGYEAAS---AAARDAGATGVT 243 Halobacterium sp. N...
14194902 197 TRRAREVLKDPYLLPDIVTQSANLALVLAGCYHGD--AELVRAGLRDVLIEPRRAPLIAGFTAAQ---QAALQADAMGAS 271 Xylella fastidiosa
20177953 184 TAEARAILPAQYRRQDCITHGRNLAGFIHACHTQQ--PDLAAKMMKDVIAEPYRTQLLPGFAAAR---QAAQDIGALACG 258 Yersinia pestis
14194909 171 TKQSRHLLPKRYSVQESVFNLSHASLMTMAIVQGK--WDLLRCCSKDRMHQYKRMQTYPVLFAIQk---LALENNALMST 245 Helicobacter pylori...
125396   307 LSGAGPTILALATEN-FEEISQEIINRFAKN-GIKCSWKLLEPAYDG-ASVEQ 356 baker's yeast
1730046  266 LSGAGPSLIALSTDS---ELPTDAVEFGAAK-GFAVTELTVGEAVRWsPTVRV 314 Mycobacterium tuberculosis
14590921 226 VSGSGPALFAIGENLkD---IGKTIVEKFEE-LGIKAEYWVTKTGRGaKT--- 271 Pyrococcus horikoshii
20177964 259 VSGAGPSILVLTDKMtDENKIVEEGTKTCNE-FNVECKVIKAKIAGGvGIEGR 310 Sulfolobus solfataricus
14194906 244 VSGSGPSVCSNINDF---EGIPYLKDVLKLR--VNNRGMIVSE---------- 281 Thermotoga maritima
13541837 251 VSGAGPSILVVYDNKtETKQMIRKISRIYEG-MGISVNFATPNVADGvREVAN 302 Thermoplasma volcanium
14194899 244 ISGSGPGVVAVCRRR-DRKRVAAALVDGFDS-AGVAASAYQTRIGDGaTRLAA 294 Halobacterium sp. NRC-1
14194902 272 ISGAGPSVFAWFQTRsAAEAAAPAVRAAFTAaGFDSQAWVTPLISPGaRLL-- 322 Xylella fastidiosa
20177953 259 ISGSGPTLFAVCNDQaTAQRMAGWLQNHYLQ-NDEGFVHICRLDTAGaRLLG- 309 Yersinia pestis
14194909 246 LSGSGSSFFNMCYE----EDAPKLKQVLSKK-FPKFRVAVLDFDNDG-VLIEK 292 Helicobacter pylori J99
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