Conserved Protein Domain Family
AKAP28
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pfam14469: AKAP28 (this model, PSSM-Id:291158 is obsolete and has been replaced by 464180)
28 kDa A-kinase anchor
28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella. Homologs of AKAP28 are present in all animals and in some, including mice the AKAP28-like domain are preceded by another uncharacterized domain
Links
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Statistics
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PSSM-Id: 291158
Aligned: 30 rows
Threshold Bit Score: 130.449
Created: 29-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O35817       374 WLTHGEFTAEKGRKQIEKFVSTWEFQN--R--WVYYADFIEKKDLIHSFHYIYRVRWSAPTAVRPMARVSANAYFTIKFN 449 Norway rat
Q28Y77       108 PTTIGSFEYSTVLSEIQDFIGLWQLSP--DtkCAVLSNPIQHDVPIKGKIYFADAHFSRPTPRCPNPLAVAKVRFIITVS 185 Drosophila pseu...
CDS27344      54 WPTMEEFTSTRGAEAIHLFIKSWNLTC--G--WLYKLTELPTKESRFWVDYCYEARFGIPTRRQPIPKHTVSVFFTLRKA 129 Hymenolepis mic...
CDI97518     144 WPTNEAFTPELGAEKIKLYIKSWDLTC--G--WVYALKMLPSKEKRFWTEYYYEVRFSIPTRRQPIPKYTVSVFFTLRRA 219 Echinococcus mu...
XP_002063512 143 WMRIGEFAYNNVISEIRDFITKWQLSPdtK--CVVLSNMRRHDVPVKGSIYFVDAHFSRPTPRCPNPLAVAKVRFIISVS 220 Drosophila will...
XP_002048913 122 WLKIGEFEYNNVLAVIRDFIGKWQLSP--KtkCVVLTNTRRHDVALKGTIYFVDAHFSRPTQRCPNPLAVAKVRFIITVS 199 Drosophila virilis
XP_002080670  48 MLTIGDFEYSNAIADIRDFVSRWELSPdtK--CVVISNPIRHEVAQKGTILFVDAHFSRPTPRCPNPLAVAKVRFIISVS 125 Drosophila simu...
XP_001995343 121 WQTIDQFEYGNVVAMIRHYIGLWQVSPqtK--CVVLSNRRGREVALKGQIYFVDAHFSRPSQTCTNPLAVAKVRFIITVS 198 Drosophila grim...
XP_003389725  39 iPTGPEINPEECMETIEELIKSWDLDG--S--WLHHTSYTGVRSVGGRAIHSFSVMFSQPSRRKPAPRATASVFFFF-IV 113 Amphimedon quee...
XP_004987911 114 aLTADELNWDSAKLIIETVVEGWAISD--M--WKYHV----AKEAEGAGYVQACVTWSIPMRRRPVPNATAYTMFNLNKT 185 Salpingoeca ros...

O35817       450 KSKPADMPVDVSYIFENSELLQR------P------GKIRFREQWLRDITETKHILL 494 Norway rat
Q28Y77       186 KLVPKHYPVMITYRFEGYNTLYY------AvgersqSSSSFQRFYIDTILHTKLAFY 236 Drosophila pseudoobscura
CDS27344     130 YCKPKDAKIEVTFAIESLRQKHE------P------DKCVFNEEWLKMILESKANLg 174 Hymenolepis microstoma
CDI97518     220 RCKPRKTPIDVCYVVESLSQKNR------P------GEHVFNEEWLKMVLEYKAKLg 264 Echinococcus multilocularis
XP_002063512 221 KVMQKHYPVMITYRFEGFNTLYY------AigeratNSWTFQRFHIDTILHSKLHFY 271 Drosophila willistoni
XP_002048913 200 SVMQKYYPVMITYRFEGYRTLYY------AvgdralTLNTFQRFYIDTILHTKLSFY 250 Drosophila virilis
XP_002080670 126 KILLKHYPVMITYRFEGYNTLYYglgercL------NSFTFQRFYIDTILHTKLTFF 176 Drosophila simulans
XP_001995343 199 RILPKHYPVMITYRFEGYRTLYY------AlgeravNSNSFQRLYIDTILHSKLSFY 249 Drosophila grimshawi
XP_003389725 114 EGEGTETSTTVFYVVESQRVVLR------P-------STPFREVWLRKIISSKLEIn 157 Amphimedon queenslandica
XP_004987911 186 -----EHGISVEWQLEQQRLKHD------A------TQP-CREQWLHDVVASKRIVH 224 Salpingoeca rosetta
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