Conserved Protein Domain Family
Whi5

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pfam08528: Whi5 
Whi5 like
In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the retinoblastoma Tudor suppressor protein (Rb) alleviates repression of E2F and thereby activates G1/S transcription. The cell size regulator Whi5 appears to be an analogous target of CDK activity during G1 phase.
Statistics
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PSSM-Id: 285700
View PSSM: pfam08528
Aligned: 82 rows
Threshold Bit Score: 37.3178
Threshold Setting Gi: 205831279
Created: 26-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam08528 is a member of the superfamily cl07231.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20
                 ....*....|....*....|....
gi 74609006  151 LKTRLNYALMKLQNGWVDKSLPEL 174
gi 205831279 101 LQIRLQFAYYKYITNQIDSKFKDI 124
gi 685942757  26 LQTRLKLASYKARNGLVNTPVDSI 49
gi 588258653  26 LQARLRLASYKARNGLVSTPIDSI 49
gi 366987295 111 LKIRLQFALYKFNTKQTMLKFKQI 134
gi 365991559 130 LQIRLQFALFKYNTNQTTLSFKEL 153
gi 254579813  90 LRVRLQFAYYKYKTNQTDQRFKDI 113
gi 367004236  98 LKIRLQFAFYKYQTNQIDKKFTDI 121
gi 403215312 127 LQVRLQFAYYKLVTSQTDLKFADL 150
gi 254569020  60 LKTRLQLAVFKIQTNQLSLNVDDL 83
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