Conserved Protein Domain Family
RecQ5
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pfam06959: RecQ5 (this model, PSSM-Id:284397 is obsolete and has been replaced by 399738)
RecQ helicase protein-like 5 (RecQ5)
This family represents a conserved region approximately 200 residues long within eukaryotic RecQ helicase protein-like 5 (RecQ5). The RecQ helicases have been implicated in DNA repair and recombination, and RecQ5 may have an important role in DNA metabolizm.
Links
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Statistics
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PSSM-Id: 284397
Aligned: 13 rows
Threshold Bit Score: 322.208
Created: 26-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6P4G0       598 KSCSAQAEPPEPNEYDIPPASHVYSLKPKRVGAGFPKGSCPFQTATELMETTRIREQAPQPERGGEHEPPSRPCGLLDED 677  human
Q8VID5       626 KSCGAAAEFSEPSDYDIPPTSHVYSLKPKRVGAGFSKGPCSFQTATELLGKSHSQKQAPEAMLEGGQEPPGWVCDLQDED 705  house mouse
XP_006912283 624 KSCSAPAEPPEPTEYDIPPASQVYSLKPKRVGAGFPKGSCQFQTATELMEKTLAKGEAPQPVPGGEQEPPGRPCDLQGED 703  black flying fox
XP_540436    622 RSCSMHAQPPEPTEYDIRPASQVYSLKPKRVGAGFPRGSCPFQTATELMEKTQAEERAPQPVQEGKREPPSQPCGLQDED 701  dog
XP_003786174 625 KSCSAQAEPSEYDEYDIPPTSHVYSLKPKRVGAGFPKGSCTFQTATELMETSQIQEQAPQPMRGDEQETPNQPGGLKDKD 704  small-eared ga...
XP_008511507 624 KSCSAQVEHPEPTEYDIPPASQVYSLKPKRVGAGFPKGSYPFQTATELMEKMRPKEQAPQPVWGGKQEPPSRPCGLQDED 703  Equus przewalskii
XP_005332622 626 KSCSGQAEPPEPNEYDIPPASHVYSLKAKRVGAGFPKGSCPFQTATELMEKSRTQESS-QPVQGDEKEPPSQPSGIQDKD 704  thirteen-lined...
XP_004748970 623 RSCTEPAQPSEPTEYDILPASLVYSPKPRRVGAGFPRGSCSFQTATELMEKTCAKEQAPQPARGGEQEPPSQPCGLQQED 702  domestic ferret
XP_003461465 624 eSCSAQVEPPEPNEYDIPPASHMYSFKAKRTGAGFLKGSSPFQTATELMGKSHTQEQAPQPTEGGEPEAPSQLCVLQDED 703  domestic guine...
NP_001179255 624 sSCSAQAEPPEPTEHDILPASQVYSLKPKRVGAGFPKGSCLFQTATELMEKTWVPEQEPRPKQGGERGAPSQPCDCQGAE 703  cattle
XP_006103499 632 KSRSA---PAEPTEHDILPASQVYSLKPKRVGAGFPKGSIPFQTASQLMEEMRAGGQAPRPEQKGEQEPPSQPRGLQDEE 708  little brown bat
XP_008249172 626 KKRSAQAEPSEPSEYDIPPASQVYSLKAKRVGAGFPKGSCLFQTATELMGKTQPQDGAPQPVQREEQEPPSQPCALQDEG 705  rabbit
XP_007615870 626 KSCSAGVEPSEPNDYDVPPTSHIYSLKPKRVGAGFPKGASPFQTATELLGK-----QAPKGVPGGEQGPPSWCCDYQDED 700  Chinese hamster

Q6P4G0       678 GSEPLPGPRGEVP------GGSAHYGGPSPEKKAKSSSGGSslAKGRASKKQQLLATAAHKDSQSIARFFCRRVESPALL 751  human
Q8VID5       706 RSKPHPGYQEKAL------GSSVNCGDPSPEKKTKGSSQGS--AKARASKKQQLLATAARKDSQNITRFLCQRTESPPLP 777  house mouse
XP_006912283 704 SSEPNPRLRGEAP------RSSAHCGGPSPKKKAKGPSRGSaiAKTRANKKQQLLATAACKDSQSITRFFCQGAESPAPR 777  black flying fox
XP_540436    702 CSKALPGPRAEAP------GSSFHCGGSSPEKTGKSPSKGGplAKARASKKQQLLAAAALKDSQNITRF-CLRAKSPSPL 774  dog
XP_003786174 705 RSIPLPGPSKETP------GDSAHWEGPSPEKKARGFSGGSsaAKARANKKQQLLATAAHKDSQNITRFFYQRVESPPRL 778  small-eared ga...
XP_008511507 704 STEPLPGPRGEAPgssascGSSASCGESSPEKKAKGPTGGSpiAKARVNKKQQLLAAAALKDSQNITRFFCQRAKSPPPL 783  Equus przewalskii
XP_005332622 705 VSEGLPGPKGEDP------GGSAHCAGPSAEK-VKASSRSSsvTKARASKKQQLLATAAQKDSQNIARFFCQRAENPPPL 777  thirteen-lined...
XP_004748970 703 CSEPFPGPGGEAP------GSRAHCRGSSPETVKSSSTKGS--AKARASKKQQLLAAAALKDSQNIARF-CQRAKSPSPL 773  domestic ferret
XP_003461465 704 RSVLLPGPSEEAP------AGRAYCGGPSPEKKLKGSCGNRsvAKAQASKKQQLLATAAHKGSQNITRFFCQRVANPLVL 777  domestic guine...
NP_001179255 704 PAKSLPGPQGEAP------RSGAVCRGPSPEE-ERGPARGSptAKARVNKKQQLLAAAALKDSQNIARFFCRRTKSPPPV 776  cattle
XP_006103499 709 SSEPVPGLR-EAP------GSSAHCGGPSPEK-AKGPSGGSpaAKARANKKQQLLAAAALKDSQNIARFFCQRAESPPAL 780  little brown bat
XP_008249172 706 CSEPLPGPRPKAS------GGGAHCGGPSPEKKAKGSPGSQsvAKTSASKKQQLLAAAARKDSQDITRFFCQRAGSP--- 776  rabbit
XP_007615870 701 RNKPLPENQREAP------GSSVNCGELSPQKRTKGSSQGS--VRAGASKKQQLLAAAALKDSQSITRFLCQRAESLPSP 772  Chinese hamster

Q6P4G0       752 ASAPEAEGA--CPSCEGvqg-ppmA-PEKYTgEEDG--AGGHSPAPPQTeECLR 799  human
Q8VID5       778 ASVPRSEDA--SPSCGD-------V-PGKCT-QEVG--AQGHLVAVFQT-EGPR 817  house mouse
XP_006912283 778 TSAPGAKGA--SPSCEGvrg-ppaVtPEKCTgEEDG--APGHLAACAQTkERTR 826  black flying fox
XP_540436    775 TSAPGAEDAgpGPSCEGmrg-ppaA-PEKCAgEEDG--ALGCLAAHPQTkECTR 824  dog
XP_003786174 779 ASAPRAKDA--SPSCEGaqg-ppmA-PEK----EDG--AQRCLNAPPRTeENTi 822  small-eared galago
XP_008511507 784 MSALPAEGA--SPSSEGvrg-pptA-PEKCAgEEDG--ALGHLAVPAQTeECTR 831  Equus przewalskii
XP_005332622 778 TTAPRADGA--SPSCGRkqe-plmT-SEKCTeEESG--LRGYLMDPPQTeACPS 825  thirteen-lined ground squirrel
XP_004748970 774 TSAPGAEGA--GPSCEGvrg-ppaA-PEECSgEEDG--ALGCLAVPSQTkECTR 821  domestic ferret
XP_003461465 778 SAALRAEGA--SLSCEGvqg-pfmA-PEKNTeKKDG--AQGHITA-LHTeKFSG 824  domestic guinea pig
NP_001179255 777 TAAPGADGT--SPSRDGarg-pltF-LEKGSgQEDG--AVGHLAARPETkECAE 824  cattle
XP_006103499 781 ASAPGAEGA--SPSCAKvrgplavA-PETCTgEEDG--ALGRSAACPQT-ECTR 828  little brown bat
XP_008249172 777 --APGAEDA--SPACGGvqe----tpPEKCAeEEDGarAQGRLPAPLQTeECPG 822  rabbit
XP_007615870 773 APGPRSGDV--TPSCGG-------E-PEDCT--QVG--AQAHLSARVQT-ECPR 811  Chinese hamster
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