Conserved Protein Domain Family
IL17

?
pfam06083: IL17 
Click on image for an interactive view with Cn3D
Interleukin-17
IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.
Statistics
?
PSSM-Id: 283690
View PSSM: pfam06083
Aligned: 95 rows
Threshold Bit Score: 58.3921
Threshold Setting Gi: 321472801
Created: 13-Jul-2015
Updated: 5-Aug-2015
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam06083 is a member of the superfamily cl05558.
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2VXS_A        51 RSTSPWNLHR-NEDPERYPSVIWEAKCRHLG--CI-N---ADGNV--DYHMNSVPIQQEILVLRRep---phCPNSFRLE 118
gi 779999157 103 dgMCPWTYVE-CFDPDRIPMSISMAQCQCSA--CL-Dp--YSHQA--DPNLRCQPIFHNMKVLRKtqc--vdGLYRYEEE 172
gi 780019951 108 nSVCPWTYIH-CSDPGRIPEVIAVAQCRCST--CL-Dp--YTHRP--DQNLVCQSIMYKMKVLRRtph--asGQYRYHVA 177
gi 779999168  96 ngLCPWTYVE-CFDADRIPMGLQVAQCQCSG--CL-Dp--YTHTP--NPNLQCTPVKRNIKVLKKtqc--agGMYKYEEQ 165
gi 780053113 241 RALCPFVMET-DTDVERYPQDILSARCACPD--CI-Np--YNNGFirNPGVDCMPVVREMETLRRgqc--vdGVYRYEKQ 312
gi 260818936  94 RSMCKWRYED-NVDPNRFPSTLKVAVKEYTGsrCR-Dp--ATGAP--RADLACLPIDYELNVLRKn------SEGEWQES 161
gi 765826412  80 tSICP-TYRVtDVDVNRIPQTIVQRRCKCTE--CL-SvldSTLGP--RAFSRCVPTFQYQMVLRRvgc--asGVFEYKPV 151
gi 260818978 169 RSVCPWRYDD-DFKANRFPHTLRVAVKTHTGsrCI-Dp--ATGAP--RRDLRCLPVEYKLNVLRKds----eeVWQISAD 238
gi 260798530  94 RAYCPWQVIV-DSNPNRFPTDIAYARCQSTF-----Ps--QDGEY--NWTMACDSVTYTKPVLVReecsgadNTYRYKCV 163
gi 321443304 143 frTCPSQLVA-VKRQDRFPNVRLFAKCLCRK--CLgNt--ITSYP--YSSSTCLPVKVLMPVLIRshssgqqSDAEWKFF 215
                         90
                 ....*....|.
2VXS_A       119 KILVSVGCTCV 129
gi 779999157 173 TVKVPVACGCM 183
gi 780019951 178 TEDVPVACACl 188
gi 779999168 166 NLAVPVACACM 176
gi 780053113 313 TTKVPVACVCa 323
gi 260818936 162 YEFVTIGFTCa 172
gi 765826412 152 MEPFVVGCSCk 162
gi 260818978 239 PEFVTVGYTCa 249
gi 260798530 164 HLTVPNACVAV 174
gi 321443304 216 LEPVSVSCVCg 226
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap