Conserved Protein Domain Family
Mak16
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pfam04874: Mak16 (this model, PSSM-Id:282698 is obsolete and has been replaced by 461462)
Mak16 protein C-terminal region
The precise function of this eukaryotic protein family is unknown. The yeast orthologues have been implicated in cell cycle progression and biogenesis of 60S ribosomal subunits. The Schistosoma mansoni Mak16 has been shown to target protein transport to the nucleolus.
Links
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Statistics
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PSSM-Id: 282698
Aligned: 140 rows
Threshold Bit Score: 54.5674
Created: 24-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6FUT9       145 APKVKRREMNRERKALVAAKIEESISKELLNRLKSGAYSNadktltPLNVDENIWNKIMGkLgeedmegVSAdEEEEESD 224 Candida glabrata
EFO62317     137 KKKAERRDMLRQAKALAAAQIEKTIQKELLTQLKEGKYDE------IYNFSTLAYKSLVTeTa-----gKKPvKFHEDEE 205 Giardia lamblia...
XP_001704336 137 KKKAERRDMLRQAKALAAAQIEKTIQKELLTQLKEGKYDE------IYNFSTLAYKSLVTeTa-----gKKPvKFHDNEE 205 Giardia lamblia...
EFA78854     137 KKKTERRDAAREQKAMVAAQLTVNIKKELIERLNKDAYGN------MYYFPEKIVNDVLLsEgv----qDENeEAEEEME 206 Polysphondylium...
XP_004355462 139 QKKADRRDARREQKAMVAAQLTVNIKKELLERLKKKTYGD------LYYFPEKVFNEVLee------dgEQDeMNSEEEE 206 Dictyostelium f...
XP_003291496 137 NKKAERRDKTRENKALVAAHLTVNIKKELLSRLSKGTYSE------MNYFPEEVFNEVLnkegdqdeldEEEiEEEEELE 210 Dictyostelium p...
KFG40566     138 KQKTERREKAREKKAEVAAHLEDVIESELLKRLQQGVYGT------LYNFESEKTAEA-----------EADqEEEEVKQ 200 Toxoplasma gond...
CDI82996     138 KKKTERREAAREKKALVAAHIEDVIEDELLKRLHQGVYGD------LYNE-------------------HRLtKETTQEE 192 Eimeria acervulina
XP_001388315 138 KKKTERREASREHKALNAAKIENEIENELLLRLKEGLY-Dg-----IYNYPTNNFEKTLDnLen---vtQDEvSNGDSLE 208 Cryptosporidium...
XP_004023885 153 KKKAERRDKIREQKALIAANLEEQIEKELIERLKDGVY-Ed-----IYNFNKNAFKKVMDdQe----------IYEQEEE 216 Ichthyophthiriu...

Q6FUT9       225 VE----------------REIEYIE-DT-Ee-----eEEVDLDNLEK 248 Candida glabrata
EFO62317     206 SEgrtrkerevsteeeyeyekqerepvraaa---------------- 236 Giardia lamblia P15
XP_001704336 206 SE----------------Grmqkerevsteeeyeyekqerepvraaa 236 Giardia lamblia ATCC 50803
EFA78854     207 QE-----------------LDQYIEgDDeEyeeeyedEDEAEQDLEd 236 Polysphondylium pallidum PN500
XP_004355462 207 EEfeee--------meegGATEYVDgGSdEef----yDDDEDDEdyd 241 Dictyostelium fasciculatum
XP_003291496 211 EEyedeid-----dlengGDIEYVEg-----------DDDEFDDddd 241 Dictyostelium purpureum
KFG40566     201 DKaekrgvvafeeedeeeELSEYSEsEGsEdfd--fdESDEEEDIED 245 Toxoplasma gondii GAB2-2007-GAL-DOM2
CDI82996     193 KEtpevtt----akaaetGAIRFEAaAEtDe------EEFASSDFEl 229 Eimeria acervulina
XP_001388315 209 NE-----------------LAEYIEgIDdD-------SEDELEAmhk 231 Cryptosporidium parvum Iowa II
XP_004023885 217 GEekdea------seeniSDAEFVY-Dp---------NQQYSDDDnl 247 Ichthyophthirius multifiliis
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