2IP4,1GSO,3MJF,3LP8,2YRW,2YW2,1VKZ,2XD4


Conserved Protein Domain Family
GARS_C
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pfam02843: GARS_C (this model, PSSM-Id:280930 is obsolete and has been replaced by 460722)
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Phosphoribosylglycinamide synthetase, C domain
Phosphoribosylglycinamide synthetase catalyzes the second step in the de novo biosynthesis of purine. The reaction catalyzed by Phosphoribosylglycinamide synthetase is the ATP- dependent addition of 5-phosphoribosylamine to glycine to form 5'phosphoribosylglycinamide. This domain is related to the C-terminal domain of biotin carboxylase/carbamoyl phosphate synthetase (see pfam02787).
Links
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Statistics
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PSSM-Id: 280930
Aligned: 1165 rows
Threshold Bit Score: 41.641
Created: 10-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2IP4_A       322 AACVVLAAPGYPESPRKGIPLhvpep--pegvlVFHAG--------Trre-ggrLVSAGGRVLNVVGLGRDLKEALERAY 390 Thermus thermop...
Q8EZT7       335 AVVVVLAAQGYPDFYEKNIPLnlpets-gqnvhLFHAG--------Tlkk-dgkVFSSGGRILGIVAQGADLKSSVDQAY 404 Leptospira inte...
WP_013774214 329 nLGVVVAAKDYPGEYKKEETIseirl--kenqqIYYAGvde--tdgT-------LVTAGGRLFLIESSGDTLKEASENVY 397 Melissococcus p...
WP_013668834 327 SLGVVLAAEGYPGTYQKGMVLdelitklpdglqIYGAGvel--regH-------YEAKGGRILMLVAKGSSYEICRDQVY 397 Aerococcus urinae
WP_014939389 323 yLGVMVSAPGYPTSPKQHIALpddl-----prnIFYAGvte--edgK-------LYSSGGRIFTLYNHASTLECAQAKVY 388 Lactobacillus b...
WP_015432524 325 SLGVIVAAEGYPQDYAKGMEIsfadd--fpmdnVCFAG--------Vaek-dgkLTANGGRILMVTTQQDDLISARKAVY 393 Bibersteinia tr...
WP_016611031 327 SIGVVIASQGYPGKYQQGMPVpspqg---egtqFFYAGveetadqgD-------LTAAGGRVFLVEASAEDLATAQKNVY 396 Enterococcus ca...
EQC78703     291 SVGVVVAAEGYPETYQQGMIIpqkaa---edvqLFYAGvae--ragE-------LVAAGGRVFLAEGQGASLEEAQKKVY 358 Enterococcus sp...
WP_012387284 335 SAVVVLAAKGYPDSPEKGMVLeippn--egnvvVYHAG--------Tkrd-nssLLANGGRILGITSFGKTLKDAIDECY 403 Leptospira biflexa
WP_012369364 324 VVGVVIAANGYPEQPVTGQPVptdti--gsnllVFHAG--------TaagdddvILSAGGRVLVCVAKAKDMKQAVASVY 393 Exiguobacterium...

2IP4_A       391 AYIPQVGFP-G-AVYRRDIGRR 410 Thermus thermophilus HB8
Q8EZT7       405 SFLEKIQAP-K-TFYRKDIGYR 424 Leptospira interrogans serovar Lai str. 56601
WP_013774214 398 GCLNALRLDeDnMFYRKDIGEK 419 Melissococcus plutonius
WP_013668834 398 QFLGQHQIA-G-TFYRKDIGHW 417 Aerococcus urinae
WP_014939389 389 AELSRLDLS-G-FYYRKDIGFR 408 Lactobacillus buchneri
WP_015432524 394 ELLEKVKIE-K-SFYRRDIGYg 413 Bibersteinia trehalosi
WP_016611031 397 EAINKLPLS-G-LFYRNDIGDK 416 Enterococcus casseliflavus
EQC78703     359 QALAKMPLN-K-MFYRKDIGAK 378 Enterococcus sp. HSIEG1
WP_012387284 404 TFLSTIKAP-S-TFYRKDIGRR 423 Leptospira biflexa
WP_012369364 394 SGLDSFDRT-G-FFYRTDIAKK 413 Exiguobacterium sibiricum
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