Conserved Protein Domain Family

pfam01549: ShK 
ShK domain-like
This domain of is found in several C. elegans proteins. The domain is 30 amino acids long and rich in cysteine residues. There are 6 conserved cysteine positions in the domain that form three disulphide bridges. The domain is found in the potassium channel inhibitor ShK in sea anemone.
PSSM-Id: 279838
View PSSM: pfam01549
Aligned: 140 rows
Threshold Bit Score: 27.0171
Threshold Setting Gi: 74966271
Created: 19-Mar-2017
Updated: 23-May-2017
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
O16422 114 TCTsynaDSSSLCSDWAANGf-CTNAFytSAQRKSYCATTCKIC 156 Caenorhabditis elegans
Q9XV17  20 QCV----DYDITCYQRLDQ---Cg-----DSFTKAQCPYTCGLC 51  Caenorhabditis elegans
Q9GZE3  20 LCE----DSMITCPDLKDQ---Cd-----QGFVQSQCPYTCGIC 51  Caenorhabditis elegans
Q9GZE2  20 ECI----DKMITCPDLKDQ---Cd-----QSFVRSQCQLTCGEC 51  Caenorhabditis elegans
Q9GZE5  17 TCM----DFMIDCPRIVYY---Cd-----ETYVQNQCQFSCGIC 48  Caenorhabditis elegans
Q9GZE4  18 QCM----DTSLSCPDQVIA---Cf-----EPSVQSECPYSCATC 49  Caenorhabditis elegans
Q9GZE2  57 TCS----DTNSDCEKFHEM---Cv-----MMPYREQCPKSCGIC 88  Caenorhabditis elegans
Q9GZE3  57 QCT----DTNLDCLKFDSM---CKt----DVKYQKQCPYTCGTC 89  Caenorhabditis elegans
O45454  22 SCT----SFNGTAFIWTPAAtgCSNVI------------SDSSC 49  Caenorhabditis elegans
P30652 207 ICE----DANKMCPIWVPRGf-CSKFD--HDKVQKSCAKSCNIC 243 Caenorhabditis elegans
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