1MIZ


Conserved Protein Domain Family
FERM_M

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pfam00373: FERM_M (this model, PSSM-Id:278785 is obsolete and has been replaced by 306805)
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FERM central domain
This domain is the central structural domain of the FERM domain.
Statistics
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PSSM-Id: 278785
View PSSM: pfam00373
Aligned: 57 rows
Threshold Bit Score: 53.8113
Threshold Setting Gi: 81895295
Created: 12-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MIZ_B    5 VD-SRDPVQLNLLYVQARDDILNGSHPVS-FDKACEFAGYQCQIQFGPH--------------------------NEQKH 56   chicken
Q6TEM9   85 HL-ILQEQTRHLFFMHVKEDLHRGHLRMC-SEQAQELSALLAQAEFGDY--------------------------NQNTA 136  zebrafish
Q8SWW8   93 HF-ILQESVRNLFYMQARRDLLEGRLTAPdWSGAAKLAALLCQADGLRFnesslkadcpmrmrrelaqqqqqqqqQAQQH 171  fruit fly
Q9NDP4  122 ST-MKDEFTRYQLFMQIKLDLLERRLKCS-LSEAASIAALAVQSELGDF--------------------------NSAEH 173  vase tunicate
Q962Y3   58 SQ-LQEDITRYQLCLQIRDDILKGRLPCS-FVTHALLGSYIVQSELGDY--------------------------DPEEH 109  Belcher's lancelet
P28191  117 NR-LRDEFTRFQFYQQVRQNLEEGRLPCN-EGSLALLASYVVQAEVGDF--------------------------EEKTH 168  Caenorhabditis elegans
O94887  129 GQ-LQEEYTRYLFALQLKRDLLEERLTCA-DTTAALLTSHLLQSEIGDY-----------------------------DE 177  human
Q7Q844   98 LR-LTNNGKLML-YQQLKRDLRHGRLYCS-AGEAAALGALIVQDELGDY--------------------------DAEAH 148  Anopheles gambiae s...
Q5BZ06  122 VHdLAQSLSRYLMYLQIRRDLTQGRLLCP-ASIVGKLGALVAQAEIGDA--------------------------PTENV 174  Schistosoma japonicum
Q4SAH4   69 VA-LKEEITRYLVFLQVKRDLYHGRLLCK-TSDAALLAAYILQAEIGDY--------------------------DPGKH 120  spotted green puffe...
1MIZ_B   57 KPG---------------------------------------FLEL---------------------------------- 63   chicken
Q6TEM9  137 KY----------------------------------------WYTEl--------------------------------- 143  zebrafish
Q8SWW8  172 RLEqqrkekehvlsfkkrrlskqksmehievctlpaasttscSLQPspsasasasasasasasastsacsqthsnsssss 251  fruit fly
Q9NDP4  174 KKN---------------------------------------YVAE---------------------------------- 180  vase tunicate
Q962Y3  110 SAD---------------------------------------YLSE---------------------------------- 116  Belcher's lancelet
P28191  169 GMSrtc----------------------------------lcYKIQ---------------------------------- 180  Caenorhabditis elegans
O94887  178 TLDr-------------------------------------eHLKV---------------------------------- 186  human
Q7Q844  149 TGE---------------------------------------YVSS---------------------------------- 155  Anopheles gambiae s...
Q5BZ06  175 EVStgdvvccappslydtrln---svestefanmsttnncdqSIQEe--------------------------------- 218  Schistosoma japonicum
Q4SAH4  121 PEG---------------------------------------YCSK---------------------------------- 127  spotted green puffe...
1MIZ_B   64 ----------KDFLPK--------EYI-----KQKG-----ErKIFMAHKNC-GNMSEIEAKVRYVKLARSLKTYGVSFF 114  chicken
Q6TEM9  144 --------------------------------CGSEpnqttInSIIAKHKAL-EGLSQASVEYQALQLVSSLEHYGVEWH 190  zebrafish
Q8SWW8  252 psnsssqtglDERLASnplrvyeeYFMqpsceGEPPad-ylRqIAVEHGKLAkLQMSLKTAKYWLLKSIQDLEGYGEELF 330  fruit fly
Q9NDP4  181 ----------FRFIP-------------------NQte-efEaQVIHLHKMH-RGLSPSQAEYYFIKKSQKLEMYGIEMH 229  vase tunicate
Q962Y3  117 ----------FKFAP-------------------NQtk-elEeKVMELHKTH-KGQTPAEAELHYLENAKKLAMYGVDLH 165  Belcher's lancelet
P28191  181 ----------FATLPdd-----------------------fSdRVAELHQLH-IGQTPDVAEQNFLDHARRLEMYGMDVY 226  Caenorhabditis elegans
O94887  187 ----------NEYLPGqq---------------------hcLeKILEFHQKH-VGQTPAESDFQVLEIARKLEMYGIRFH 234  human
Q7Q844  156 -------------LKI----------------ALRQsd-qlEkKAMELHQKRdPGQEAVAVYDEFVGIARSLETYGIDPH 205  Anopheles gambiae s...
Q5BZ06  219 ---------tLDYAACc-------NMLrklkiIFNQtp-evEaQIMEEYQKL-RGLKAVEAETELLQRASQLPTYGIDPV 280  Schistosoma japonicum
Q4SAH4  128 ----------FQFFP-------------------KHse-klErRIAEIHKTElIGQCPETSELNFLQKAQMLETYGVDPH 177  spotted green puffe...
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